ID   RPOB_ARTS2              Reviewed;        1171 AA.
AC   A0JZ93;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Arth_2984;
OS   Arthrobacter sp. (strain FB24).
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Arthrobacter.
OX   NCBI_TaxID=290399;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FB24;
RX   PubMed=24501649; DOI=10.4056/sigs.4438185;
RA   Nakatsu C.H., Barabote R., Thompson S., Bruce D., Detter C., Brettin T.,
RA   Han C., Beasley F., Chen W., Konopka A., Xie G.;
RT   "Complete genome sequence of Arthrobacter sp. strain FB24.";
RL   Stand. Genomic Sci. 9:106-116(2013).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR   EMBL; CP000454; ABK04363.1; -; Genomic_DNA.
DR   RefSeq; WP_011692816.1; NC_008541.1.
DR   AlphaFoldDB; A0JZ93; -.
DR   SMR; A0JZ93; -.
DR   STRING; 290399.Arth_2984; -.
DR   PRIDE; A0JZ93; -.
DR   EnsemblBacteria; ABK04363; ABK04363; Arth_2984.
DR   KEGG; art:Arth_2984; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_3_11; -.
DR   OMA; FMTWEGY; -.
DR   OrthoDB; 9601at2; -.
DR   Proteomes; UP000000754; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 1.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 1.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..1171
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000300278"
SQ   SEQUENCE   1171 AA;  128726 MW;  526EDE3873387C02 CRC64;
     MVASSTSNVN NATAINADST DGATRRLSFA KIHEPLDVPN LLALQTDSFD WLVGNERWQA
     RVAKAVEEGD LSVATSSGLS DIFEEISPIE DFQGTMSLSF SDPEFADPKY TMAECKDRDA
     TYSAPLYVKA EFMNNNTGEI KQQTVFMGDF PLMTEKGTFV VNGTERVVVS QLVRSPGAYF
     ERTADKTSDK DIFTAKIIPS RGAWFELEID KRDQVGVRLD RKRKQSVTVL LKALGWTEGQ
     ILEEFGQYDS MRATLEKDAT ETREDALLDI YRKLRPGEPP TVEAAQSLLD NLYFNSKRYD
     LAKVGRYKIN RKLGIDRSLG DKEASVLHVE DIVAMIKFLV ALHAGEKTLT GKRDGQDHEL
     RVEIDDIDHF GNRRIRAVGE LIENQVRTGL SRMERVVRER MTTQDVEAIT PQTLINIRPV
     VAAIKEFFGT SQLSQFMDQN NPLSGLTHKR RLSALGPGGL SRDRAGMEVR DVHPSHYGRM
     CPIETPEGPN IGLIGSLASY GRINPFGFIE TPYRLVSEGV VSDEVQYLTA DDEAEVLIAQ
     ANAPLDENKK FAEETVLVRA RGGGGEPVLV PAADVEFMDV SPRQMVSVAT ALIPFLEHDD
     ANRALMGANM QRQAVPLVRS EAPFVGTGME RAAAVDAGDV VIAKKAGVVT EVSAELVIML
     NDDGTETNYR INKFARSNQG NCYNHRVLVS EGQRLEVGGI IADGPATDQG ELALGKNLLV
     AFMSWEGHNF EDAIILSQRI VAEDVLSSIH IEEHEIDARD TKLGAEEITR DIPNVSEEVL
     AGLDERGIIH IGAEVEAGDI LVGKVTPKGE TELTPEERLL RAIFGEKSRE VRDTSLKVPH
     GESGTVIGVR VFDRDNDDEL PPGVNQLVRV YVAAKRKITD GDKLAGRHGN KGVISKILPI
     EDMPFLADGT PVDIVLNPLG VPGRMNVGQV LETHLGWVAK TGWKIEGEPE WVKQLPNLPR
     ESGSTTVATP VFDGAREEEI TGLLDSTNVT RDGDRLINSS GKTRLFDGRS GEPFPDPISV
     GYMYILKLHH LVDDKIHARS TGPYSMITQQ PLGGKAQFGG QRFGEMEVWA LEAYGAAYTL
     QELLTIKSDD IHGRVKVYEA IVKGENIPEP GVPESFKVLI KEMQSLCLNV EVLSTDGTTI
     EMRDSDDAVF TAAEELGIDL SRAEPSSVEE V