ID   RPOB_AZOC5              Reviewed;        1376 AA.
AC   A8HTY8;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=AZC_0887;
OS   Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG
OS   6465 / NBRC 14845 / NCIMB 13405 / ORS 571).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Xanthobacteraceae; Azorhizobium.
OX   NCBI_TaxID=438753;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB
RC   13405 / ORS 571;
RA   Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T.,
RA   Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B.,
RA   Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.;
RT   "Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium
RT   caulinodans ORS571.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR   EMBL; AP009384; BAF86885.1; -; Genomic_DNA.
DR   RefSeq; WP_012169418.1; NC_009937.1.
DR   AlphaFoldDB; A8HTY8; -.
DR   SMR; A8HTY8; -.
DR   STRING; 438753.AZC_0887; -.
DR   PRIDE; A8HTY8; -.
DR   EnsemblBacteria; BAF86885; BAF86885; AZC_0887.
DR   KEGG; azc:AZC_0887; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_3_5; -.
DR   OMA; FMTWEGY; -.
DR   OrthoDB; 9601at2; -.
DR   Proteomes; UP000000270; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 1.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..1376
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000329164"
FT   REGION          1357..1376
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1376 AA;  153145 MW;  6F0DB9146C095872 CRC64;
     MAQTFTGRKR IRKFFGKIKE VAEMPNLIEV QKASYDQFLQ IEEPKGGRAD DGLQAVFKSV
     FPISDFSGAA MLEFVRYEFE PPKYDVDECR QRGMTFAAPL KVTLRLIVFD VDPDTGAKSV
     KDIKEQDVYT GDIPLMTMNG TFIVNGTERV IVSQMHRSPG VFFDHDKGKT HSSGKLLFAA
     RIIPYRGSWL DIEFDAKDIV YARIDRRRKI PVTSLLFALG LDSEEILNTF YEKILYTRAK
     DGWRMPFDPK RMKGYKAVAD LIDADTGEVV VEAGKKLTVR AARQLVEKGL KALKISDDEM
     VGQYIGEDIV NVHTGEIYAE AGEEITEKVL KTLGDAGFDE IPVLDIDHIN TGAYIRNTLS
     ADKNSSREEA LFDIYRVMRP GEPPTLDSAQ AMFHSLFFDA ERYDLSAVGR VKMNMRLDLD
     AEDTVRILRR EDILAVIKTL VELRDGKGEI DDIDHLGNRR VRSVGELMEN QYRVGLLRME
     RAIKERMSSV DIDTVMPQDL INAKPVAAAV REFFGSSQLS QFMDQTNPLS EITHKRRLSA
     LGPGGLTRER AGFEVRDVHP THYGRICPIE TPEGPNIGLI NSLATFARVN KYGFIEAPYR
     RVVDGRVTDE VVYLSAMEEG KYYVAQANVP LDTDGRFQED LVICRHAGDV LVVSPDRVDF
     MDVSPKQLVS VAAALIPFLE NDDANRALMG SNMQRQAVPL VRSQAPLVGT GMEAVVARDS
     GAAIAARRAG VIDQVDATRI VIRATGETDP SKSGVDIYRL MKFQRSNQST CINQRPLVRV
     GDVVKKGDII ADGPSTELGE LALGRNVLVA FMPWNGYNYE DSILLSENIV KEDVFTSIHI
     EEFEAMARDT KLGPEEITRD IPNVSEEALK NLDEAGIVYI GAEVRAGDIL VGKITPKGES
     PMTPEEKLLR AIFGEKAADV RDTSLRLPPG TTGTIVEVRV FNRHGVDKDE RALAIEREEI
     ERLAKDRDDE QAILDRNVYG RLSEMLVGKV AIAGPKAFKK DTEITKDALG EYPRSQWWLF
     AVADDALMSE LEAIRAQYDE SKKRLEQRFL DKVEKLQRGD ELPPGVMKMV KVFVAVKRKI
     QPGDKMAGRH GNKGVVSRIV PVEDMPFLED GTNVDIVLNP LGVPSRMNVG QILETHLGWA
     CAGLGRQVAA AVDAYYGSKD QQVLRNALVK VYGPDDIEVL DEKQITELGE NLRKGVPMAT
     PVFDGAHEAD IEEHLEKAGL NPSGQSTLFD GRTGEPFDRK VTVGYIYMLK LHHLVDDKIH
     ARSIGPYSLV TQQPLGGKAQ FGGQRFGEME VWALEAYGAA YTLQEMLTVK SDDVAGRTKV
     YEAIVRGEDT FESGIPESFN VLVKEMRSLG LNVELLNSKT GRQTNPGTRE NLPAAE