ID   RPOB_BORA1              Reviewed;        1370 AA.
AC   Q2L2M3;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 2.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=BAV0013;
OS   Bordetella avium (strain 197N).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=360910;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=197N;
RX   PubMed=16885469; DOI=10.1128/jb.01927-05;
RA   Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D.,
RA   Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A.,
RA   Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J.,
RA   Parkhill J., Temple L.M.;
RT   "Comparison of the genome sequence of the poultry pathogen Bordetella avium
RT   with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals
RT   extensive diversity in surface structures associated with host
RT   interaction.";
RL   J. Bacteriol. 188:6002-6015(2006).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAJ47597.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AM167904; CAJ47597.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_039052216.1; NC_010645.1.
DR   AlphaFoldDB; Q2L2M3; -.
DR   SMR; Q2L2M3; -.
DR   STRING; 360910.BAV0013; -.
DR   PRIDE; Q2L2M3; -.
DR   EnsemblBacteria; CAJ47597; CAJ47597; BAV0013.
DR   GeneID; 41391942; -.
DR   KEGG; bav:BAV0013; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_3_4; -.
DR   OrthoDB; 9601at2; -.
DR   Proteomes; UP000001977; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 1.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..1370
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000237298"
SQ   SEQUENCE   1370 AA;  153500 MW;  61FF2659AAB6B874 CRC64;
     MPYSYTEKKR IRKSFAKRED VQNVPFLLAT QLQSYLTFLQ AETATADRVN EGLQAAFTSI
     FPIVSHNGMA RLEFVSYALG EPVFDVKECQ QRGLTYASPL RAKVRLVLLD REVSKPTIKE
     VKEQEVYMGE IPLMTTTGSF VINGTERVIV SQLHRSPGVF FEHDRGKTHS SGKLLFSARV
     IPYRGSWLDF EFDPKDVLFF RVDRRRKMPV TILLKAIGMT PESILAHFFD FDNFELKSEG
     AMMEFVPERW KGEMARFDIT DRAGKVIVEK DKRINAKHLR DLANGGIQRI SVPEDFLYGR
     VLAKNVVDPD TGEVIALAND EITESVLDAM RAAKVLDLQT LYTNDLDRGP YISQTLRTDE
     TVDQTAARVA IYRMMRPGEP PTEEAVEALF QRLFYSEETY DLSRVGRMKV NSRLGRGDDA
     NGPMTLTDED ILETIKVLVE LRNGRGQIDD IDHLGNRRVR CVGELAENQF RAGLVRVERA
     VKERLGQAET ENLMPHDLIN SKPISAAIKE FFGSSQLSQF MDQTNPLSEI THKRRVSALG
     PGGLTRERAG FEVRDVHPTH YGRVCPIETP EGPNIGLINS MALYARLNEY GFLETPYRKI
     IDGRVSDQID YLSAIEESHY VIAQANAALD AEGRFVDDLV ACREAGETML TSPVNVHYMD
     VAPSQIVSVA ASLIPFLEHD DANRALMGAN MQRQAVPCLR PEKPLVGTGI ERTVAVDSGT
     TVQALRGGLV DHVDAERVVI RVNDEENVAG EVGVDIYNLI KYTRSNQNTN INQRPIVKRG
     DRVAKGDVLA DGASTDLGEL ALGQNMLIAF MPWNGYNFED SILISERVVA DDRYTSVHIE
     ELTVVARDTK LGPEEITRDI SNLAETQLNR LDESGIVYIG AEVSADDVLV GKVTPKGETQ
     LTPEEKLLRA IFGEKASDVK DTSLRVPSGM TGTVIDVQVF TREGIVRDKR AQSIIDDELR
     RYRQDLNDQL RIVENDQFDR IEKLLVGKTV NGGPRKLAKG ATVTKAYLAD LDRWQWFDIR
     LSDEPHAVVL EQAKESLEQK RHQFDLAFEE KRKKLTQGDE LPPGVLKMIK VYLAVKRRLQ
     PGDKMAGRHG NKGVVSRITP VEDMPHMADG TTADIVLNPL GVPSRMNVGQ VLEVHLGWAA
     KGVGQRIADM LQDERTAQVK NIRAYLEKVY NTTGTGARIS ELSDEEVIEL ANNLKRGVPF
     ATPVFDGATE DEITMMLELA YPDDVAKRMQ LTPSRAQAWL FDGRTGEKFE RPVTIGYMHY
     LKLHHLVDDK MHARSTGPYS LVTQQPLGGK AQFGGQRFGE MEVWALEAYG ASYTLQEMLT
     VKSDDITGRT KVYENIVKGD HVIDAGMPES FNVLVKEIRS LALDMDLERN