AB38G_ORYSJ
ID AB38G_ORYSJ Reviewed; 1509 AA.
AC Q7FMW4; Q0JJQ3;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=ABC transporter G family member 38 {ECO:0000303|PubMed:18299247};
DE Short=OsABCG38 {ECO:0000303|PubMed:18299247};
DE AltName: Full=Pleiotropic drug resistance protein 15 {ECO:0000303|PubMed:12644668, ECO:0000303|PubMed:16506311};
DE Short=OsPDR15 {ECO:0000303|PubMed:16506311};
GN Name=ABCG38 {ECO:0000303|PubMed:18299247};
GN Synonyms=PDR15 {ECO:0000303|PubMed:12644668, ECO:0000303|PubMed:16506311};
GN OrderedLocusNames=Os01g0724500 {ECO:0000312|EMBL:BAF06025.1},
GN LOC_Os01g52560; ORFNames=P0022F10.18 {ECO:0000312|EMBL:AP003229};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12644668; DOI=10.1104/pp.102.014720;
RA Jasinski M., Ducos E., Martinoia E., Boutry M.;
RT "The ATP-binding cassette transporters: structure, function, and gene
RT family comparison between rice and Arabidopsis.";
RL Plant Physiol. 131:1169-1177(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16506311; DOI=10.1016/j.febslet.2005.12.043;
RA Crouzet J., Trombik T., Fraysse A.S., Boutry M.;
RT "Organization and function of the plant pleiotropic drug resistance ABC
RT transporter family.";
RL FEBS Lett. 580:1123-1130(2006).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- FUNCTION: May be a general defense protein. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF06025.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AJ535041; CAD59563.1; -; Genomic_DNA.
DR EMBL; AP003229; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AP008207; BAF06025.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014957; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015631031.1; XM_015775545.1.
DR AlphaFoldDB; Q7FMW4; -.
DR SMR; Q7FMW4; -.
DR STRING; 4530.OS01T0724500-01; -.
DR PaxDb; Q7FMW4; -.
DR PRIDE; Q7FMW4; -.
DR GeneID; 4324722; -.
DR KEGG; osa:4324722; -.
DR InParanoid; Q7FMW4; -.
DR OrthoDB; 324553at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC_2_trans.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013581; PDR_assoc.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF08370; PDR_assoc; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1509
FT /note="ABC transporter G family member 38"
FT /id="PRO_0000234652"
FT TRANSMEM 563..583
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 598..618
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 651..671
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 682..702
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 707..727
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 733..753
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 791..811
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1252..1272
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1284..1304
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1336..1356
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1367..1387
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1397..1417
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1425..1445
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1478..1498
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 196..467
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 545..758
FT /note="ABC transmembrane type-2 1"
FT DOMAIN 908..1160
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 1233..1447
FT /note="ABC transmembrane type-2 2"
FT BINDING 229..236
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 953..960
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 1509 AA; 169853 MW; 2BD8CF351AA52BBF CRC64;
MADPQHVQEE AAGAEAVHAH AARHDGAVVM EILSRSLQSM PASPDVSAYF SGASSRRPSA
ADEVDDEEAL RWAALERLPS FDRLRTGLMR ADADSSGVGV GAVGRGRRWY AHREVDVRTL
ELAQRQAFVE RVFHVAEEDN ERFLKKLRAR IDRAGIQMPT VEVRFRNVNV QAECHVGTRA
LPTLANVSRD VGESLLGLVG LNFAKRKALH ILKDVSGIVR PSRMTLLLGP PSSGKTTLLL
ALAGKLDPTL ETSGEVTYNG YGLDEFVPQK TAAYISQHDV HAGEMTVKET LDFSAKCQGV
GQRYELLKEL AKKERQLGIY PDPEVDLFMK ATSVEGSTLQ TDYILRILGL DMCADVIVGD
ELRRGISGGQ KKRLTTAEML VGPTKVLFMD EISTGLDSST TFQIIRCIQQ IVHMGEATVL
VSLLQPAPEI FELFDDVMLL SEGQIVYQGP REHVLEFFER CGFRCPERKG VADFLQEVTS
KKDQEQYWIQ SEKPYRYVSV PEFVAKFKKF HMGKSLKKQL SVPFNKGKIH KSALVFSKQS
VSTLELLKTS CSKEWLLMKR NSFVYIFKTV QGILVALIAS TVFLRTQLNT RDEDDGQIYI
GALIFVMITN MFSGFADLSL TLARLPVFYK HRDFLFYRPW TFALPNVLVR IPSSLFESII
WVAITYYTMG FAPEASRFFK HLLVVFMLQQ MAAGLFRVTA GLCRTVVVTN TAGSLAVLIM
FVLGGFILPK DAIPKWWVWA YWCSPLTYAY IAFSSNEMHS PRWMDKFVPD GKRLGVAVLE
NSGVFTNKEW YWIATGALLG FTILFNVLFS LSLMYLNPVG KPQSILPEET DSQENIQEGK
NKAHIKQIIT VETPEPVSPN SIITLDKVIQ QLRGYSANTS DRSHSYINAA GRTAPGRGMV
LPFEPLYMSF NEINYYVDMP LEMKSQGVTA DKLQLLSGIS GAFRPGVLTA LMGVSGAGKT
TLMDVLSGRK TGGYIEGEIY ISGYPKNQAT FARISGYCEQ NDIHSPQITV RESLLFSAFL
RLPKEVNDQE KKIFVDEVME LVELTGLKDA IVGLPGVNGL STEQRKRLTI AVELVANPSI
IFMDEPTSGL DARAAAIVMR TVRNTVNTGR TVVCTIHQPS IDIFEAFDEL LLLKRGGQVI
YSGPLGTNSH KVVEYFEAIP GVPKIEENRN PATWMLDVSS AASEVRLEID FAEYYRSSTM
HQRTKALVKE LSNPPPGSDD LYFPSQYSQS TFNQFKLCLW KQWWTYWRSP DYNLVRIFFA
LFTALMLGTI FWRVGHKMES SKDLLVIIGS MYAAVLFVGF ENSVTVQPVV AVERTVFYRE
RAAGMYSAIP YALAQVVVEI PYVFVETVIY TLIVYPMMSF QWTPAKFFWF FYVSFFTFLY
FTYYGMMNVS VSPNLQVASI LGAAFYTLFN LFSGFFIPRP KIPKWWVWYY WLCPVAWTVY
GLIVSQYGDV EDFITVPGQS DQQVRPFIKD YFGYDPDFMG VVAAVLAGFT VFFAFTYAYS
IRTLNFQQR
