RPOB_CELJU
ID RPOB_CELJU Reviewed; 1361 AA.
AC B3PK30;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 77.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=CJA_0692;
OS Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp.
OS cellulosa).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Cellvibrionales;
OC Cellvibrionaceae; Cellvibrio.
OX NCBI_TaxID=498211;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ueda107;
RX PubMed=18556790; DOI=10.1128/jb.01701-07;
RA DeBoy R.T., Mongodin E.F., Fouts D.E., Tailford L.E., Khouri H.,
RA Emerson J.B., Mohamoud Y., Watkins K., Henrissat B., Gilbert H.J.,
RA Nelson K.E.;
RT "Insights into plant cell wall degradation from the genome sequence of the
RT soil bacterium Cellvibrio japonicus.";
RL J. Bacteriol. 190:5455-5463(2008).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000934; ACE84618.1; -; Genomic_DNA.
DR RefSeq; WP_012486357.1; NC_010995.1.
DR AlphaFoldDB; B3PK30; -.
DR SMR; B3PK30; -.
DR STRING; 498211.CJA_0692; -.
DR PRIDE; B3PK30; -.
DR EnsemblBacteria; ACE84618; ACE84618; CJA_0692.
DR KEGG; cja:CJA_0692; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_3_6; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000001036; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1361
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_1000141674"
SQ SEQUENCE 1361 AA; 151555 MW; 32455C411F7029E3 CRC64;
MAYSYTEKKR IRKNFGKLPH VMDVPYLLAI QLDSYRKFTQ ADLSANKRED VGLHAAFRSV
FPIVSYSGNA ALEYVSYSLG KAAFDVNECI LRGVTYAVPL RVKVRLIIYD RESANKAIKD
IKEQEVYMGE IPLMTDNGTF VINGTERVIV SQLHRSPGVF FDHDKGKTHS SGKLLYSARI
IPYRGSWLDF EFDPKDLLYV RIDRRRKLPA TILLRALNYS SQEMLSMFFE TSSFTLGKDG
QFSYEVVPSR LRGDVATFDI KDDKGNIIVE EGRRITARHI RQLEKAGVDQ MEVPSEYLLG
RSLAKDIVDT RTGELLFECN TEITSDVLSK IVAAGVEKVE TLYTNELDCG PFISETLRID
PTRTQLEALV EIYRMMRPGE PPTKESAEAL FQNLFFSQER YDLSAVGRMK FNRRLGRETE
TGEGTLSNDD IVDVMKTLIS IRNGKGVVDD IDHLGNRRVR SVGEMAENQF RVGLVRVERA
VKERLSMAES EGLMPQDLIN AKPVAAAVKE FFGSSQLSQF MDQNNPLSEI THKRRVFALG
PGGLTRERAG FEVRDVHPTH YGRVCPIETP EGPNIGLINS LATYARTNNY GFLESPYRKV
IEGKVTDQIE YLSAINESEY VIAQASASLD DNGRLTEELV SVRHQNEFTL KAPTDVQYMD
VSARQVVSVA ASLIPFLEHD DANRALMGSN MQRQAVPTLR SQKPLVGTGM ERNVAADSGV
CVVAKRGGVI DSVDAGRIVV KVHDAEVEAG DAGVDIYNLI KYTRSNQNTC INQRPIVSMG
DIVSRGDILA DGPSVDMGEL ALGQNMRIAF MPWNGYNFED SILVSERVVQ EDRFTTIHIQ
ELTCIARDTK LGSEEITADI PNVGESALSK LDESGIVYIG AEVGGGDILV GKVTPKGETQ
LTPEEKLLRA IFGEKASDVK DTSLRVPSGT KGTVIDVQVF TRDGLEKDQR SLEIEKAQLD
EVRKDLNEEF RIVETATFER LRAALVGQIV ASGKGVKKGE ALTHDILDGL EKDQWFKLRM
NEDALNEQID RAEEQLAERR KILDERFEDK KRKLSTGDDL APGVLKIVKV YLAIKRRIQP
GDKMAGRHGN KGVISVIMPV EDMPYDENGE TVDIVLNPLG VPSRMNVGQV LEMHLGMAAK
GLGVKINKLI QEQKAVADIR SFLEEIYNST GDVAAKEDLV SFSDREVIDL AKNLVDGVPM
ATPVFDGAKE HEIKALLRLA SLSDTGQTTL FDGRTGDQFS RSVTVGYMYM LKLNHLVDDK
MHARSTGSYS LVTQQPLGGK AQFGGQRFGE MEVWALEAYG AAYTLQEMLT VKSDDVAGRT
KMYKNIVDGD HRMEPGMPES FNVLVKEIRS LGINIELEQE D
