RPOB_CHESB
ID RPOB_CHESB Reviewed; 1379 AA.
AC Q11HB3;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Meso_1819;
OS Chelativorans sp. (strain BNC1).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Chelativorans; unclassified Chelativorans.
OX NCBI_TaxID=266779;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BNC1;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.;
RT "Complete sequence of chromosome of Mesorhizobium sp. BNC1.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000390; ABG63212.1; -; Genomic_DNA.
DR RefSeq; WP_011581155.1; NC_008254.1.
DR AlphaFoldDB; Q11HB3; -.
DR SMR; Q11HB3; -.
DR STRING; 266779.Meso_1819; -.
DR PRIDE; Q11HB3; -.
DR EnsemblBacteria; ABG63212; ABG63212; Meso_1819.
DR KEGG; mes:Meso_1819; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_3_5; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 2.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 2.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW Transferase.
FT CHAIN 1..1379
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000300345"
SQ SEQUENCE 1379 AA; 154227 MW; 81CEEAF0D1301024 CRC64;
MAQTQTFNGR RRVRKFFGKI PEVAEMPNLI EVQKASYDQF LMVEEPQGGR PDEGLQAVFK
SVFPISDFAG TAMLEFVKYE FEAPKFDTEE CRQRDLTYAA PLKVTLRLIV FDIDEDTGSK
SIKDIKEQDV YMGDMPLMTD NGTFIINGTE RVIVSQMHRS PGVFFDHDKG KSHSSGKLLF
AARVIPYRGS WLDIEFDAKD IVYARIDRRR KIPVTSLLMA LGMDGEEILS TFYNKLTFIR
DGDNWRVPFS AERFRGMKAT ADIIDADTGE VVLEAGKKMT ARMARQLADK GLKAIRATED
DLLGNYLAED IVNMKTGEIF LEAGDEIDEK TLKILLETAG NEVKFLDIDH VNIGGYIRNT
LVADKNESRQ DALFDIYRVM RPGEPPTLET AEAMFHSLFF DAERYDLSAV GRVKMNMRLE
LDCPDTVRVL RSEDMVAVVR TLVELRDGKG EIDDIDNLGN RRVRSVGELM ENQYRLGLLR
MERAIKERMS SIEIDTVMPQ DLINAKPAAA AVREFFGSSQ LSQFMDQTNP LSEITHKRRL
SALGPGGLTR ERAGFEVRDV HPTHYGRICP IETPEGPNIG LINSLATFAR VNKYGFIETP
YRKIVDGKVT EEVVYLSAME EAKHYVAQAN ATIDENGGFA DEFVVCRHAG EVIMAPRENV
DLMDVSPKQL VSVAAALIPF LENDDANRAL MGSNMQRQAV PLVRAEAPFV GTGMEPVVAR
DSGAAIAARR TGVVDQVDAT RIVIRATEDV DASQSGVDIY RLQKFQRSNQ NTCINQRPLV
RVGDLINKGD IIADGPSTDL GDLALGRNVL VAFMPWNGYN YEDSILLSER IVRDDIFTSI
HIEEFEVMAR DTKLGPEEIT RDIPNVSEEA LKNLDEAGIV YIGAEVQPGD ILVGKITPKG
ESPMTPEEKL LRAIFGEKAS DVRDTSMRMP PGTYGTVVEV RVFNRHGVEK DERAMAIERE
EIERLAKDRD DEQSILDRNV YARLSEMLIG KEAIAGPKGF KKGGALTKEL LGEYPRSQWW
QFAVEDEKLQ SELEALRAQY DESKNALQQR FMDKVEKVQR GDEMPPGVMK MVKVFVAVKR
KMQPGDKMAG RHGNKGVVSR IVPIEDMPFL EDGTHVDIVL NPLGVPSRMN VGQILETHLG
WACAGMGRQI GELIDAYKEA GDIKPLRAKI ESLIPDNDRN EPVRQYDDES VVRLSEQLRR
GVSIATPVFD GAHESDINEM LEEAGLNSSG QVTLYDGRTG EEFDRKVTVG YIYMLKLHHL
VDDKIHARSI GPYSLVTQQP LGGKAQFGGQ RFGEMEVWAL EAYGAAYTLQ EMLTVKSDDV
AGRTKVYEAI VRGDDTFEAG IPESFNVLVK EMRSLGLNVE LENSSRFDTP PAQLPEAAE
