RPOB_CHLAA
ID RPOB_CHLAA Reviewed; 1227 AA.
AC A9WH12;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 1.
DT 03-AUG-2022, entry version 77.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Caur_0874;
OS Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC Bacteria; Chloroflexi; Chloroflexia; Chloroflexales; Chloroflexineae;
OC Chloroflexaceae; Chloroflexus.
OX NCBI_TaxID=324602;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29366 / DSM 635 / J-10-fl;
RX PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT "Complete genome sequence of the filamentous anoxygenic phototrophic
RT bacterium Chloroflexus aurantiacus.";
RL BMC Genomics 12:334-334(2011).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000909; ABY34107.1; -; Genomic_DNA.
DR RefSeq; WP_012256763.1; NC_010175.1.
DR RefSeq; YP_001634496.1; NC_010175.1.
DR AlphaFoldDB; A9WH12; -.
DR SMR; A9WH12; -.
DR STRING; 324602.Caur_0874; -.
DR EnsemblBacteria; ABY34107; ABY34107; Caur_0874.
DR KEGG; cau:Caur_0874; -.
DR PATRIC; fig|324602.8.peg.1003; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_1_0; -.
DR InParanoid; A9WH12; -.
DR OMA; FMTWEGY; -.
DR Proteomes; UP000002008; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1227
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000329168"
SQ SEQUENCE 1227 AA; 137772 MW; 48929BEF18908EE5 CRC64;
MPPLIESVVL QPLIAPIDPG ADGRRSRRIE RRSFARIKDA IDLPLLIETQ LKSFEWFKRE
GLRELFDEIS PITDFTGKNL ELHFRDYTFG EPRYDEFECR ERDLTYAAPL RVRVELRILT
TGEIKESEIF LGDFPIMTDN GTFVYNGAER VVVSQLIRSP GVYFKDEKEP TSGRSLHTAK
LIPNRGAWLE FETNKRDVIS VKVDRKRKIP VTILLRAITA WIAEENGNGR WVPDNELDKF
GHNDQIIELF RHVDTVPEHP YIHATLDKDP SRNAKEALLE LYKRLRPGDP PTLENARSLI
ESLLFSPRRY DLAKVGRYKL NKNLWERDVR RDGAKAPDLS VRVLLPRDIF RIVEQLILLN
NGHGRPDDID HLGNRRVRTV GELIQQQFRV GLLRLERVVK ERMSLQDPAS ATPNGLINIR
PVVAAMREFF GGSQLSQFMD QTNPLAELTN KRRLSALGPG GLSRDRAGFE VRDVHHSHYG
RICPVETPEG PNIGLIGTMS TFARVNEMGF LETPYRKVYN SVDNVQVWKE KGILLRDVRD
LRTGDLIAAK GTRVNDEIAR QITIGLLRGQ ILREDIVDPD TDELIAEAGT EINRALAERI
VELPIKHIKI RPVVSQEVDY LSADEEDRFV IVQANAPLDQ HNRFLDTIVS CRFGEDFVSE
RVERVDYMDV SPKQVVSVST SLIPFLEHDD ANRALMGSNM QRQAVPLLRP DAPIVGTGME
YRAARDSGQV IVARRDGVVV STTSERIVIE EDDGNQTEYR LRKFMRSNQD TCINQRPAVV
RGQRVKAGDV IADSSSTDQG ELALGQNVLV AYMPWEGGNF EDAILVSERL VREDIFTSIH
IEKYEVEARD TKLGPEEITR DIPNVGQESL RNLDERGIIY IGAEVQPNDI LVGKITPKGE
TDLTAEERLL RAIFGEKARE VKDSSLRVPN GVRGKVIDVK VFSRSEGAEL PVGVNQTVRV
LLCQKRKISA GDKMAGRHGN KGVVSRVLPI EDMPFLPDGR PVDIILNPIG VPSRMNIGQI
LETHLGWAAA RLGFRVATPV FDGAHEDQIK DLLVQAGLPA DGKVTLYDGR TGERFDNPVT
VGYAYMLKLA HLVEDKIHAR STGPYSLVTQ QPLGGKAQFG GQRFGEMEVW ALEAYGAAYT
LQEMLTVKSD DVVGRVKTYE AIVKGEPIQE AGVPESFKVL IKELQSLGLS VEVLSADEKP
VELSDDLDSD IGALEGINLS GMERGEF
