RPOB_CHLCH
ID RPOB_CHLCH Reviewed; 1300 AA.
AC Q3ATP5;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Cag_0357;
OS Chlorobium chlorochromatii (strain CaD3).
OC Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC Chlorobium/Pelodictyon group; Chlorobium.
OX NCBI_TaxID=340177;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CaD3;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F.,
RA Land M., Kyrpides N., Ivanova N., Richardson P.;
RT "Complete sequence of Chlorobium chlorochromatii CaD3.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000108; ABB27630.1; -; Genomic_DNA.
DR RefSeq; WP_011361403.1; NC_007514.1.
DR AlphaFoldDB; Q3ATP5; -.
DR SMR; Q3ATP5; -.
DR STRING; 340177.Cag_0357; -.
DR PRIDE; Q3ATP5; -.
DR EnsemblBacteria; ABB27630; ABB27630; Cag_0357.
DR KEGG; cch:Cag_0357; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_1_10; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 2.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 3.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW Transferase.
FT CHAIN 1..1300
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000224045"
SQ SEQUENCE 1300 AA; 145666 MW; 876A75DB1C2D1312 CRC64;
MADATTSRID FSKIKSIINS PDLLKVQLDS FHNFIQDSVP LAKRKDQGLE RVLRGAFPIT
DTRGLYLLEY ISYAFDKPKY TVEECIERGL TYDVSLKVKL KLSYKDEADE PDWKETIQQE
VYLGRIPYMT ERGTFIVNGA ERVVVAQLHR SPGVVFSEAV HPNGKKMFSA KIVPTRGSWI
EFQTDINNQI FVYIDQKKNF LVTALLRAIG FARDEDILAL FDLVEEVSLK ASKREQLVGQ
YLASDIVDMQ TGEVISARTA ITEEIFEQIL LAGYKSIKVM KSFSNNEKGM DKSVIINTIL
NDSSATEEEA LEIVYEELRA NEAPDIEAAR SFLERTFFNQ KKYDLGDVGR YRIKKKLRRE
FEELYSFIGE KPELKALSDT IEEKILQTIQ TYSDEPIGED ILVLTHYDII AVIYYLIKLV
NGQAEVDDVD HLANRRVRSV GEQLAAQFVV GLARMGKNVR EKLNSRDSDK IAPSDLINAR
TVSSVVSSFF ATSQLSQFMD QTNPLAEMTN KRRVSALGPG GLTRERAGFE VRDVHYTHYG
RLCPIETPEG PNIGLISSLS VYAEINDKGF IQTPYRLVDN GQVTDTVVML SAEDEENKIT
VPVSIPLDEN NRIAVETVQA RTKGDYPVVA ATDVHYMDVS PVQIVSAAAA LIPFLEHDDG
NRALMGANMQ RQAVPLLTSD APVVGTGMEG KVARDSRAVI VAEGPGEVVD VTADYIQVRY
QLDADNNLRL SMLDPDEGLK TYKLIKFKRS NQDTCISQKP LVRIGDKVEK NTVLADSSST
EYGELALGKN VLVAFMPWRG YNFEDAIILS ERLVYDDVFT SIHIHEFEAN VRDTKRGEEQ
FTRDIYNVSE EALRNLDENG IVRCGAEVKE RDILVGKITP KGESDPTPEE KLLRAIFGDK
SSDVKDASMH VPAGMKGIII KTKLFSRKKK IGLDIKEKIE LLDKQFAAKE YDLRKRFAKW
LKHFLDGKTS TGVYNDKGKV VVPEGTVFEE SVLAKFATAQ FLESVDLSRG VVSSDKTNKN
VTRLIKEFRF LLKDIADERE NEKYKVNVGD ELPPGIEELA KVYIAQKRKI QVGDKMAGRH
GNKGVVGKIL PVEDMPFMAD GTPVDIVLNP LGVPSRMNIG QLYETSLGWA AKKLGVKFKT
PIFNGATYEE VQRELERAGL PTHGKVSLFD GRTGERFDDE VTVGYIYMLK LSHLVDDKIH
ARSTGPYSLI TQQPLGGKAQ FGGQRFGEME VWALEAYGAS NILREMLTVK SDDVVGRNKT
YEAIVKGQNL PEPGIPESFN VLVRELQGLG LEIRIDDKVP
