ID   RPOB_CHLCV              Reviewed;        1252 AA.
AC   Q822J1;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=CCA_00691;
OS   Chlamydia caviae (strain ATCC VR-813 / DSM 19441 / 03DC25 / GPIC)
OS   (Chlamydophila caviae).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=227941;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-813 / DSM 19441 / 03DC25 / GPIC;
RX   PubMed=12682364; DOI=10.1093/nar/gkg321;
RA   Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T.,
RA   Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A.,
RA   Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O.,
RA   Salzberg S.L., Hsia R.-C., McClarty G., Rank R.G., Bavoil P.M.,
RA   Fraser C.M.;
RT   "Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC):
RT   examining the role of niche-specific genes in the evolution of the
RT   Chlamydiaceae.";
RL   Nucleic Acids Res. 31:2134-2147(2003).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR   EMBL; AE015925; AAP05433.1; -; Genomic_DNA.
DR   RefSeq; WP_011006648.1; NC_003361.3.
DR   AlphaFoldDB; Q822J1; -.
DR   SMR; Q822J1; -.
DR   STRING; 227941.CCA_00691; -.
DR   EnsemblBacteria; AAP05433; AAP05433; CCA_00691.
DR   KEGG; cca:CCA_00691; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_1_0; -.
DR   OMA; FMTWEGY; -.
DR   OrthoDB; 9601at2; -.
DR   Proteomes; UP000002193; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.40.270.10; -; 2.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 1.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW   Transferase.
FT   CHAIN           1..1252
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000047878"
SQ   SEQUENCE   1252 AA;  140261 MW;  71257FD1C0C77115 CRC64;
     MFKCPERVSV KKKEDILDLP NLIEIQIKSY KQFLQIGKLA EERDNVGLEE VFREIFPIKS
     YNEATILEYL SYNLGVPKYS PEECIRRGIT YSVTLKVRFR LTDETGIKEE EVYMGTIPIM
     TDKGTFIING AERVIVSQVH RSPGINFEQE KHSKGNILFS FRIIPYRGSW LEAIFDINDL
     IYIHIDRKKR RRKILAMTFI RALGYSSDAD IIEEFFQIEE RSLKSEKDFT LLVGKILADN
     VLDESSSLVY GKAGEKLSTA MLKRMLDADI STLKIAVEAD ENHPIIKMLA KDPTDSYEAA
     LKDFYRRLRP GEPATLANAR STIMRLFFDS KRYNLGRVGR YKLNRKLGFP MDEETLSQVT
     LRKEDVIGAL KYLIRLKMGD ERASIDDIDH LANRRVRSVG ELIQNQCRSG LARMEKIVRE
     RMNLFDFSSD TLIPGKIISA KGLASVLKDF FGRSQLSQFM DQTNPVAELT HKRRLSALGP
     GGLNRERAGF EVRDVHASHY GRICPIETPE GPNIGLITSL SSFAKINEFG FIETPYRIVR
     DGVVTDEIEY MTADVEEECV IAQASAALDE YNMFVDPVCW ARCRGEAFEA DTSTVTHMDV
     SPKQLVSIVT GLIPFLEHDD ANRALMGSNM QRQAVPLLKT EAPIVGTGLE ARAAKDSGAI
     VVAEEDGVVD YVDGYKVVIA PKHNPTLKRT YDLKKFLRSN SGTCINQRPL CSVGDVIVKG
     DVIADGPATD QGELALGKNI LVAFMPWYGY NFEDAIIISE KLIKQDAYTS IYIEEFELTA
     RDTKLGKEEI TRDIPNVSEE VLANLGEDGI IRIGAEVKPG DILVGKITPK SETELAPEER
     LLRAIFGEKA ADVKDASLTV PPGTEGVVMD VKVFSRKDRL SKSDDELVEE AVHLKDLQKG
     YKNQVSVLKT EYREKLGALL LNEKAPASII HRRTADILVQ EGTVFDQETI ELLEQESLVD
     LLMPPCEMYD VLKGLLSDYE TSLQRLEVNY KTEVEHIREG DADLDHGVIR QVKVYVASKR
     KLQVGDKMAG RHGNKGVVSK IVPEADMPYL ANGETVQMIL NPLGVPSRMN LGQVLETHLG
     YAAKTAGIHV KTPVFEGFPE SRIWDMMIEQ GLPADGKSYL YDGKTGERFD NTVVIGYIYM
     LKLSHLIADK IHARSIGPYS LVTQQPLGGK AQMGGQRFGE MEVWALEAYG VAHMLQEILT
     VKSDDVSGRT RIYESIVKGE NLLKSGTPES FNVLIKEMQG LGLDVRPMVV DA