RPOB_CHLPD
ID RPOB_CHLPD Reviewed; 1312 AA.
AC A1BD23;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321};
GN OrderedLocusNames=Cpha266_0233;
OS Chlorobium phaeobacteroides (strain DSM 266).
OC Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC Chlorobium/Pelodictyon group; Chlorobium.
OX NCBI_TaxID=290317;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 266;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.,
RA Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T.,
RA Overmann J., Bryant D.A., Richardson P.;
RT "Complete sequence of Chlorobium phaeobacteroides DSM 266.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000492; ABL64300.1; -; Genomic_DNA.
DR RefSeq; WP_011744140.1; NC_008639.1.
DR AlphaFoldDB; A1BD23; -.
DR SMR; A1BD23; -.
DR STRING; 290317.Cpha266_0233; -.
DR PRIDE; A1BD23; -.
DR EnsemblBacteria; ABL64300; ABL64300; Cpha266_0233.
DR KEGG; cph:Cpha266_0233; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_1_10; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000008701; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 2.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 3.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1312
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000300298"
SQ SEQUENCE 1312 AA; 147002 MW; 20A9CA9521A3F567 CRC64;
MQFDKSEVHV KVADATPTPC IDFSKIQSVI DPPDLLKVQL DSFHNFIQDS VPLAKRRDQG
LERVLRSAFP ITDTRGLYLL EYISYSFDKP KYTVEDCIER GLTYDVSLKV KLKLSYKDEP
DEADWKETIQ QEVYLGRIPY MTERGTFIVN GAERVVVAQL HRSPGVVFSE AIHPNGKKMY
SAKIVPTRGS WIEFQTDINN QIFVYIDQKK NFLVTALLRA IGFAKDEDIL GLFDLVEEVK
ITSAKKEQLI GQYLASDIVD MQTGEVVSAR TAITEDIVDQ IIAAGYKSVR VMKSFSGNDK
GPDKSIIINT ILNDNSATEE EALEIVYEEL RANEAPDIDA ARSFLERTFF NQKKYDLGDV
GRYRIRKKLS KEFEELHGYL DGQPELKKLS DTIYEKILHT IQSFSDEPIG GDILVLTHYD
IIAVIYYLIK LVNGQAEVDD VDHLANRRVR SVGEQLAAQF VIGLARMGKN VREKLNSRDS
DKIAPSDLIN ARTVSSVVSS FFATSQLSQF MDQTNPLAEM TNKRRVSALG PGGLTRERAG
FEVRDVHYTH YGRLCPIETP EGPNIGLISS LSVYAEINDK GFIQTPYRVV TNGVVTDTVL
MLSAEDEENK ITVPVSIPLD ENMKIAIESV QARTKGDYPL VPAEDVNYMD VSPVQIVSAA
AALIPFLEHD DGNRALMGAN MQRQAVPLLT AEAPIVGTGM ESKVARDSRS VILAEGDGIV
DDVTAEYIKV RYDIDADTDV RLSLLDPDEG LKTYKLIKFK RSNQDTCISQ KPLIHIGQRV
SKGDVLADSS STENGELALG KNVLVAFMPW RGYNFEDAII LSERLVYDDV FTSIHIHEFE
ANVRDTKRGE EQFTRDIYNV SEDALRNLDE NGIVRIGAEV KERDILVGKI TPKGESDPTP
EEKLLRAIFG DKSSDVKDAS MHVPAGMKGI VIKTKLFSRK KKVGLDIKEK IEILEKKYDY
KEYDLRKKFL KRLKQLLEGK TSTGIYSDKG KLLVAEDAVY DDSVLERFTA IPFLESIDFV
KGVTQSEKVN ENVMLLVKEF RLKLKDLNDE RDNEKYKLNV GDELPPGIEE LAKVYIAQKR
KIQVGDKMAG RHGNKGVVGK ILPIEDMPFM ENGKPVDIVL NPLGVPSRMN IGQLYETSLG
WAGKELGVKF KTPIFNGATY QEVQQELEKA GLPSHGKVSL YDGRTGEQFD DEVTIGYIYM
LKLSHLVDDK IHARSTGPYS LITQQPLGGK AQFGGQRFGE MEVWALEAYG AANILREMLT
VKSDDVIGRN KTYEAIVKGQ NLPEPGTPES FNVLVRELQG LGLEIRIDDR VP
