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ATRAP_XENTR
ID   ATRAP_XENTR             Reviewed;         163 AA.
AC   Q5EBF8; Q28G84;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Type-1 angiotensin II receptor-associated protein-like;
GN   Name=agtrap; ORFNames=TGas011p03.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=F6;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Appears to be a negative regulator of angiotensin II type I
CC       receptor-mediated signaling. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; CR761507; CAJ83948.1; -; mRNA.
DR   EMBL; BC089687; AAH89687.1; -; mRNA.
DR   RefSeq; NP_001015751.1; NM_001015751.1.
DR   AlphaFoldDB; Q5EBF8; -.
DR   PaxDb; Q5EBF8; -.
DR   Ensembl; ENSXETT00000028675; ENSXETP00000028675; ENSXETG00000013094.
DR   GeneID; 548468; -.
DR   KEGG; xtr:548468; -.
DR   CTD; 57085; -.
DR   Xenbase; XB-GENE-482876; agtrap.
DR   eggNOG; ENOG502S36M; Eukaryota.
DR   HOGENOM; CLU_126745_0_0_1; -.
DR   InParanoid; Q5EBF8; -.
DR   OMA; GPDARGY; -.
DR   OrthoDB; 1325275at2759; -.
DR   PhylomeDB; Q5EBF8; -.
DR   TreeFam; TF324477; -.
DR   Proteomes; UP000008143; Chromosome 7.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000013094; Expressed in testis and 12 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0038166; P:angiotensin-activated signaling pathway; IEA:InterPro.
DR   GO; GO:0008217; P:regulation of blood pressure; IBA:GO_Central.
DR   InterPro; IPR009436; AGTRAP.
DR   PANTHER; PTHR16521; PTHR16521; 1.
DR   Pfam; PF06396; AGTRAP; 1.
DR   SMART; SM00805; AGTRAP; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..163
FT                   /note="Type-1 angiotensin II receptor-associated protein-
FT                   like"
FT                   /id="PRO_0000064739"
FT   TOPO_DOM        1..28
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        50..55
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        77..95
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        117..163
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   163 AA;  18624 MW;  36C0C5163238F7DC CRC64;
     MELPAVNLKA IVFTHWLLTV FACMIDWLPK AYGLANITIL AMGVWAIAQR DSIDAIFMFL
     IGLLLTILTD ILLFALYFTE AEKASESGPL RDLFRFSSGM GIFSLLLKPL SCFFMYHMYR
     ERGGEYFVNL GFITLSRDRS SYQSIEHMDP PADQDNKLPS RTY
 
 
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