ATRAP_XENTR
ID ATRAP_XENTR Reviewed; 163 AA.
AC Q5EBF8; Q28G84;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Type-1 angiotensin II receptor-associated protein-like;
GN Name=agtrap; ORFNames=TGas011p03.1;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Gastrula;
RG Sanger Xenopus tropicalis EST/cDNA project;
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=F6;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Appears to be a negative regulator of angiotensin II type I
CC receptor-mediated signaling. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; CR761507; CAJ83948.1; -; mRNA.
DR EMBL; BC089687; AAH89687.1; -; mRNA.
DR RefSeq; NP_001015751.1; NM_001015751.1.
DR AlphaFoldDB; Q5EBF8; -.
DR PaxDb; Q5EBF8; -.
DR Ensembl; ENSXETT00000028675; ENSXETP00000028675; ENSXETG00000013094.
DR GeneID; 548468; -.
DR KEGG; xtr:548468; -.
DR CTD; 57085; -.
DR Xenbase; XB-GENE-482876; agtrap.
DR eggNOG; ENOG502S36M; Eukaryota.
DR HOGENOM; CLU_126745_0_0_1; -.
DR InParanoid; Q5EBF8; -.
DR OMA; GPDARGY; -.
DR OrthoDB; 1325275at2759; -.
DR PhylomeDB; Q5EBF8; -.
DR TreeFam; TF324477; -.
DR Proteomes; UP000008143; Chromosome 7.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000013094; Expressed in testis and 12 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0038166; P:angiotensin-activated signaling pathway; IEA:InterPro.
DR GO; GO:0008217; P:regulation of blood pressure; IBA:GO_Central.
DR InterPro; IPR009436; AGTRAP.
DR PANTHER; PTHR16521; PTHR16521; 1.
DR Pfam; PF06396; AGTRAP; 1.
DR SMART; SM00805; AGTRAP; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..163
FT /note="Type-1 angiotensin II receptor-associated protein-
FT like"
FT /id="PRO_0000064739"
FT TOPO_DOM 1..28
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 50..55
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 77..95
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 117..163
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 163 AA; 18624 MW; 36C0C5163238F7DC CRC64;
MELPAVNLKA IVFTHWLLTV FACMIDWLPK AYGLANITIL AMGVWAIAQR DSIDAIFMFL
IGLLLTILTD ILLFALYFTE AEKASESGPL RDLFRFSSGM GIFSLLLKPL SCFFMYHMYR
ERGGEYFVNL GFITLSRDRS SYQSIEHMDP PADQDNKLPS RTY