ID   RPOB_EIMTE              Reviewed;        1059 AA.
AC   Q7YN57;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta;
DE            EC=2.7.7.6;
DE   AltName: Full=PEP;
DE   AltName: Full=Plastid-encoded RNA polymerase subunit beta;
DE            Short=RNA polymerase subunit beta;
GN   Name=rpoB;
OS   Eimeria tenella (Coccidian parasite).
OG   Plastid; Apicoplast.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX   NCBI_TaxID=5802;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Penn State;
RX   PubMed=14636990; DOI=10.1016/j.gene.2003.08.008;
RA   Cai X., Fuller A.L., McDougald L.R., Zhu G.;
RT   "Apicoplast genome of the coccidian Eimeria tenella.";
RL   Gene 321:39-46(2003).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6;
CC   -!- SUBUNIT: In plastids the minimal PEP RNA polymerase catalytic core is
CC       composed of four subunits: alpha, beta, beta', and beta''. When a
CC       (nuclear-encoded) sigma factor is associated with the core the
CC       holoenzyme is formed, which can initiate transcription (Potential).
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Plastid, apicoplast.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000305}.
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DR   EMBL; AY217738; AAO40248.1; -; Genomic_DNA.
DR   RefSeq; NP_852647.1; NC_004823.1.
DR   AlphaFoldDB; Q7YN57; -.
DR   SMR; Q7YN57; -.
DR   GeneID; 1263703; -.
DR   VEuPathDB; ToxoDB:ETH2_API05200; -.
DR   VEuPathDB; ToxoDB:ETH_00013935; -.
DR   VEuPathDB; ToxoDB:ETH_00019030; -.
DR   GO; GO:0020011; C:apicoplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 2.40.270.10; -; 1.
DR   Gene3D; 2.40.50.150; -; 1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
PE   3: Inferred from homology;
KW   Apicoplast; DNA-directed RNA polymerase; Nucleotidyltransferase; Plastid;
KW   Transcription; Transferase.
FT   CHAIN           1..1059
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000300454"
SQ   SEQUENCE   1059 AA;  124754 MW;  E9AEB3A8034CF2A3 CRC64;
     MNFQLKNFLI LKTLKTFYIE YYKVLIYYLI NSIKNYLGDK LYLYYKKNKY TIYILSDFLF
     FKTTNLTSNI TDTVQEFNSK ILIFLPLKIK NLKNNKYKII YYLLGEIPKY TIEKNLIING
     LKKTFISKLM FNYIGIFFNK FIKNNNNILY AKIIFNDKFI INIVLEENKC YCIFNNYKYD
     LICFLYLLGI SMQDIFIFSR YNKSFYLKKL LLTLPSLNIN NIINYNIFKY LSFFFNLSFK
     LNTYYIFNKV LNKNNSLYSY IKNFSNSNNL IALDFINILD ILLDIKYNKK NITDLDLLEY
     RSIFTLGNYF TNQYSFYLKK FSNILHNDIF KCIKNLEKYK LNTNSFKSKL YFNLKEYLTV
     NPLVQYLEQI NSFSEIIHKN RVTNYNSKLK QNLQIRNINL NQLGSLCLID TTEGINCGLV
     ISFTKNIKIE KRNNFQFPYL PVLNIKTKNF ITFINSFLQQ TYIVLFNNYY LRKNKLFNFF
     NLSLNKNSFK LKNISIQNMI YIKPMDMFSF AENLIPFIFY NDPARVLMGA KMQSQIVPIL
     KNKRSIIITG YEKNLLNSTN LILKAYQEGI VVYVSSYKII IRDLYNRKIT YFLDKYKRSN
     HFTILHSKPN VWQGERIFCG QILTSTQDIL FSEYIGGNNL LVSYGNFFGY NFEDAIVLNK
     KIIYSQLFTS LHFKVYEIIF NSLNKFSFEI STINLPKKSF YSKRNLDFFG IIKEGSKVLN
     NDILVSKIFI TNINISLLPL YNLIYILFGK EIKNIKDKSI LVSFGNSGRI VKTELFSYSS
     KIKSYLGYYL KCRVYICKQR LLSVGDKLCG RYGNKGIIAY ILPSNDLPYT NTGIIPDIIS
     DSLGIPSRMN IGQLFENLFG LSCYFLNKRL CISNTFNLPK VYIKTILYNY INNIKEKSGN
     LWIYNSYSPG KILLRDGRQG YKLSEPSFLG ISKYSKLIHM IKDKIHYRTI GPYTELMQQP
     VKGRNKKGGQ RFGEMEIWAI EAYGSSYNLR ELLNYKSDDI IARTSLLSNL DNNIILDNIT
     TTESFRTLIR EIHSMNLNIE AFSSIDQLEG KILPININF