RPOB_FLAPJ
ID RPOB_FLAPJ Reviewed; 1270 AA.
AC A6GYU0;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=FP1176;
OS Flavobacterium psychrophilum (strain ATCC 49511 / DSM 21280 / CIP 103535 /
OS JIP02/86).
OC Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=402612;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49511 / DSM 21280 / CIP 103535 / JIP02/86;
RX PubMed=17592475; DOI=10.1038/nbt1313;
RA Duchaud E., Boussaha M., Loux V., Bernardet J.-F., Michel C., Kerouault B.,
RA Mondot S., Nicolas P., Bossy R., Caron C., Bessieres P., Gibrat J.-F.,
RA Claverol S., Dumetz F., Le Henaff M., Benmansour A.;
RT "Complete genome sequence of the fish pathogen Flavobacterium
RT psychrophilum.";
RL Nat. Biotechnol. 25:763-769(2007).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; AM398681; CAL43263.1; -; Genomic_DNA.
DR RefSeq; WP_011963312.1; NC_009613.3.
DR RefSeq; YP_001296074.1; NC_009613.3.
DR AlphaFoldDB; A6GYU0; -.
DR SMR; A6GYU0; -.
DR STRING; 402612.FP1176; -.
DR EnsemblBacteria; CAL43263; CAL43263; FP1176.
DR GeneID; 66553080; -.
DR KEGG; fps:FP1176; -.
DR PATRIC; fig|402612.5.peg.1193; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_1_10; -.
DR OMA; FMTWEGY; -.
DR Proteomes; UP000006394; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.40.270.10; -; 3.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1270
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000300314"
SQ SEQUENCE 1270 AA; 142492 MW; BD3B2C2DE3D49F90 CRC64;
MITNQTERLN FASTKNIPAY PDFLDVQVKS FQDFFQLETK SDERGNEGLY NTFMENFPIT
DTRNNFVLEF IDYFVDPPRY TIQECIERGL TYSVPLKARL KLYCTDPEHE DFETIVQDVY
LGTIPYMTPS GTFVINGAER VVVSQLHRSP GVFFGQSFHA NGTKLYSARV IPFKGSWIEF
ATDINSVMYA YIDRKKKLPV TTLFRAIGFQ SDKDILEIFD LAEEIKVSKS GLKKYIGRKL
AARVLNTWHE DFVDEDTGEV VSIERNEIIL DRDTILDKDN VEEIVESNVK SILLHKEDNN
VVDYSIIHNT LQKDPTNSEK EAVEHIYRQL RNAEPPDEET ARGIIDKLFF SDQRYNLGEV
GRYRINKKLG LDTPMEKQVL TKEDIITIVK YLIELINAKA DIDDIDHLSN RRVRTVGEQL
SQQFGVGLAR MARTIRERMN VRDNEVFTPI DLINAKTLSS VINSFFGTNQ LSQFMDQTNP
LAEITHKRRL SALGPGGLSR ERAGFEVRDV HYTHYGRLCP IETPEGPNIG LISSLGVYAK
VNGMGFIETP YRKVTNGVVD LTSVPKYLSA EEEEGMLIAQ ANIQMDENGK ITADNVIARQ
EGDFPVIDPT AVHYTDVAPN QIASISASLI PFLEHDDANR ALMGSNMMRQ AVPLIRPEAP
IVGTGLERQV ASDSRVLINA EGAGVVEYVD ADMITIKYDR TDAERAVSFE SDEKTYKLIK
FRKTNQGTSI NLKPIVRKGD KVIKGQVLCE GYATQNGELA LGRNLKVAFM PWKGYNFEDA
IVISEKVVRD DIFTSIHVDD YSLEVRDTKL GNEELTNDIP NVSEEATKDL DENGMIRIGA
EVKPGDILIG KITPKGESDP TPEEKLLRAI FGDKAGDVKD ASLKASPSLH GVVLDKKLFA
RAVKDKRKRT QDKDALSDLE MEFEVKFVEL KDKLVDKLFT IVNGKTSQGV MNDLGEEVLP
KGKKYTQKML YAVEDFAHLT RGQWVADDET NKMVNDLIHN YKIKLNDLQG ALRREKFTIT
VGDELPAGIL KLAKVYIAKK RKLKVGDKMA GRHGNKGIVA RIVRHEDMPF LEDGTPVDIV
LNPLGVPSRM NIGQIYETVL GWAGQNLGRK YATPIFDGAS LDQINAITDE AGVPRFGHTH
LYDGGTGERF HQAATVGVIY MLKLGHMVDD KMHARSIGPY SLITQQPLGG KAQFGGQRFG
EMEVWALEAY GASSTLREIL TVKSDDVIGR AKTYEAIVKG ETMPEPGLPE SFNVLMHELK
GLGLDIRLEE
