RPOB_FRAAA
ID RPOB_FRAAA Reviewed; 1141 AA.
AC Q0RRT0;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=FRAAL1072;
OS Frankia alni (strain ACN14a).
OC Bacteria; Actinobacteria; Frankiales; Frankiaceae; Frankia.
OX NCBI_TaxID=326424;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACN14a;
RX PubMed=17151343; DOI=10.1101/gr.5798407;
RA Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A.,
RA Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P.,
RA Goltsman E., Huang Y., Kopp O.R., Labarre L., Lapidus A., Lavire C.,
RA Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J.,
RA Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F.,
RA Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C.,
RA Benson D.R.;
RT "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT reflect host range and host plant biogeography.";
RL Genome Res. 17:7-15(2007).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CT573213; CAJ59737.1; -; Genomic_DNA.
DR RefSeq; WP_011602294.1; NC_008278.1.
DR AlphaFoldDB; Q0RRT0; -.
DR SMR; Q0RRT0; -.
DR STRING; 326424.FRAAL1072; -.
DR PRIDE; Q0RRT0; -.
DR KEGG; fal:FRAAL1072; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_3_11; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000000657; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 1.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1141
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000300320"
SQ SEQUENCE 1141 AA; 126703 MW; E7D82B636D3F01FE CRC64;
MAASRSSSRI SFAKIIEPLE VPDLLALQTQ SFDWLIGSDA WAERVQEAID SGRDDVPITS
GLEEVFEEIS PIEDFSGSMS LSFRDHRFEP PKYSVEECKD KDMTFSAPLF VTAEFTNNTT
GEIKSQTVFM GDFPLMTPKG TFVINGTERV VVSQLVRSPG VYFERSLDKA SDKDLYSCKV
IPSRGAWLEF EIDKRDTVGV RIDRKRRQSV TVLLKALGWD EARILERFGD FPSMRITLEK
DHTASQDDAL LDIYRKLRPG EPPTRESAQT LLENLFFNPK RYDLAKVGRY KVNKKLTLEI
AHDVGVLTED DIVRTIEYVV KLHAGADPAE YEVDDIDHFG NRRLRTVGEL IQNQVRLGLA
RMERVVRERM TTQDVEAITP QTLINIRPVV ASIKEFFGTS QLSQFMDQTN PLAGLTHKRR
LSALGPGGLS RERAGFEVRD VHPSHYGRMC PIETPEGPNI GLIGSLSTFA RVNPFGFVET
PYRKVVNGRV TDQIDYLTAD EEDRHVKAQA NTPLSPDGTF AEDRVLVRRK GGEVEFIPPD
EVDYMDVSPR QMVSVATAMI PFLEHDDANR ALMGSNMQRQ SVPLLRSEAP LVGTGMEARA
AKDAGDVVVC VQAGVVEDLS ADYITVMHDD GTRRTYRLAK FRRSNQGTCI NQKPIVFEGD
RVEAGQVIAD GPCTDNGEMA LGKNLLVAFM PWEGHNYEDA IILSQRLVQD DVLSSIHIEE
HEVDARDTKL GPEEITRDIP NVAEEVLADL DERGIIRIGA EVSPGDVLVG KVTPKGETEL
TPEERLLRAI FGEKAREVRD TSLKVPHGES GKVIGVRVFS REDGDELPPG VNELVRVYVA
QKRKITDGDK LAGRHGNKGV IAKILPQEDM PFLEDGTPVD IVLNPHGVPR RMNIGQILET
HLGWVAKTGW QVDAGTEDWK ERLRGIGADS STPGTNVATP VFDGAREEEI TGLLDSTLPN
RDGVQLIGSS GKATLFDGRT GEPYPYPVAV GYIYILKLLH LVDDKIHARS TGPYSMITQQ
PLGGKAQFGG QRFGEMEVWA LEAYGAAYAL QELLTIKSDD VVGRVKVYEA IVKGENIPEP
GIPESFKVLI KEMQSLCLNV EVLSSDGVQI EMRDTDEDVF RAAEELGIDL SRREPSSVEE
V
