RPOB_FRASN
ID RPOB_FRASN Reviewed; 1141 AA.
AC A8LC64;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321};
GN OrderedLocusNames=Franean1_6057;
OS Frankia sp. (strain EAN1pec).
OC Bacteria; Actinobacteria; Frankiales; Frankiaceae; Frankia;
OC unclassified Frankia.
OX NCBI_TaxID=298653;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EAN1pec;
RX PubMed=17151343; DOI=10.1101/gr.5798407;
RA Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A.,
RA Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P.,
RA Goltsman E., Huang Y., Kopp O.R., Labarre L., Lapidus A., Lavire C.,
RA Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J.,
RA Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F.,
RA Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C.,
RA Benson D.R.;
RT "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT reflect host range and host plant biogeography.";
RL Genome Res. 17:7-15(2007).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000820; ABW15401.1; -; Genomic_DNA.
DR RefSeq; WP_020463484.1; NC_009921.1.
DR AlphaFoldDB; A8LC64; -.
DR SMR; A8LC64; -.
DR STRING; 298653.Franean1_6057; -.
DR PRIDE; A8LC64; -.
DR EnsemblBacteria; ABW15401; ABW15401; Franean1_6057.
DR KEGG; fre:Franean1_6057; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_1_11; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 1.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW Transferase.
FT CHAIN 1..1141
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_1000141697"
SQ SEQUENCE 1141 AA; 126613 MW; 1E3AD9DA9555BA37 CRC64;
MAASRSASRI SFAKIIEPLE VPDLLALQTQ SFDWLIGNDI WAERVQEAID ADRNDVPITS
GLEEVFEEIS PIEDFSGSMS LSFRDHRFEP PKYSVEECKD KDMTYSAPLF VTAEFTNNTT
GEIKSQTVFM GDFPLMTPKG TFVINGTERV VVSQLVRSPG VYFEKAIDKA SDKDLFSCKV
IPSRGAWLEF EIDKRDTVGV RIDRKRRQSV TVLLKALGWD EARILERFGD FPSMRVTLEK
DHTSSQDDAL LDIYRKLRPG EPPTRESAQT LLENLFFNPK RYDLAKVGRY KVNKKLTLEV
AHDVGVLTED DVVRTIEYIV KLHAGQDPDN YEVDDIDHFG NRRLRTVGEL IQNQVRLGLA
RMERVVRERM TTQDVEAITP QTLINIRPVV ASIKEFFGTS QLSQFMDQTN PLAGLTHKRR
LSALGPGGLS RERAGFEVRD VHPSHYGRMC PIETPEGPNI GLIGSLSTFA RVNPFGFVET
PYRKVENGRV TGQIDYLTAD EEDRHVKAQA NTPLNADGTF AEDRVLVRRK GGEVEFIPPD
EVDYMDVSPR QMVSVATAMI PFLEHDDANR ALMGSNMQRQ SVPLLRSEAP LVGTGMEARA
AKDAGDVVVC AQSGVVEDLS ADYITVMHDD GTRRTYRLAK FRRSNQGTCI NQKPIVFEGD
RVEAGQVIAD GPCTDNGEMA LGKNLLVAFM PWEGHNYEDA IILSQRLVQD DVLSSIHIEE
HEVDARDTKL GPEEITRDIP NVAEEVLADL DERGIIRIGA EVSPGDVLVG KVTPKGETEL
TPEERLLRAI FGEKAREVRD TSLKVPHGES GKVIGVRVFS REDGDELPPG VNELVRVYVA
QKRKITDGDK LAGRHGNKGV IAKILPVEDM PFLPDGTAVD VVLNPHGVPR RMNIGQILET
HLGWVAKTGW QVDSGAEGWK ERLRGIGADA APPGTNVATP VFDGAREEEI TGLLDATLPN
RDGQQMIGSS GKAELYDGRT GEPYPYPVAV GYIYILKLLH LVDDKIHARS TGPYSMITQQ
PLGGKAQFGG QRFGEMEVWA LEAYGAAYAL QELLTIKSDD VVGRVKVYEA IVKGENIPEP
GIPESFKVLI KEMQSLCLNV EVLSSDGVSI EMRDTDEDVF RAAEELGIDL SRREPSSVEE
V
