AB39G_ORYSJ
ID AB39G_ORYSJ Reviewed; 1444 AA.
AC Q8GU88; Q0E2W5;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=ABC transporter G family member 39 {ECO:0000303|PubMed:18299247};
DE Short=OsABCG39 {ECO:0000303|PubMed:18299247};
DE AltName: Full=Pleiotropic drug resistance protein 7 {ECO:0000303|PubMed:12644668, ECO:0000303|PubMed:16506311};
DE Short=OsPDR7 {ECO:0000303|PubMed:16506311};
GN Name=ABCG39 {ECO:0000303|PubMed:18299247};
GN Synonyms=PDR7 {ECO:0000303|PubMed:12644668, ECO:0000303|PubMed:16506311};
GN OrderedLocusNames=Os02g0208300 {ECO:0000312|EMBL:BAF08173.2},
GN LOC_Os02g11760;
GN ORFNames=OJ1003_F05.29-1 {ECO:0000312|EMBL:BAD24998.1},
GN OJ1006_A02.12-1 {ECO:0000312|EMBL:BAD25007.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12644668; DOI=10.1104/pp.102.014720;
RA Jasinski M., Ducos E., Martinoia E., Boutry M.;
RT "The ATP-binding cassette transporters: structure, function, and gene
RT family comparison between rice and Arabidopsis.";
RL Plant Physiol. 131:1169-1177(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16506311; DOI=10.1016/j.febslet.2005.12.043;
RA Crouzet J., Trombik T., Fraysse A.S., Boutry M.;
RT "Organization and function of the plant pleiotropic drug resistance ABC
RT transporter family.";
RL FEBS Lett. 580:1123-1130(2006).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- FUNCTION: May be a general defense protein. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF08173.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AJ535048; CAD59570.1; -; Genomic_DNA.
DR EMBL; AP003974; BAD24998.1; -; Genomic_DNA.
DR EMBL; AP003977; BAD25007.1; -; Genomic_DNA.
DR EMBL; AP008208; BAF08173.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014958; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; Q8GU88; -.
DR SMR; Q8GU88; -.
DR STRING; 4530.OS02T0208300-01; -.
DR PaxDb; Q8GU88; -.
DR PRIDE; Q8GU88; -.
DR InParanoid; Q8GU88; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC_2_trans.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013581; PDR_assoc.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF08370; PDR_assoc; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1444
FT /note="ABC transporter G family member 39"
FT /id="PRO_0000234649"
FT TRANSMEM 522..542
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 555..575
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 610..630
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 642..662
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 667..687
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 754..774
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1192..1212
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1220..1240
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1278..1298
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1305..1325
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1335..1355
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1362..1382
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1414..1434
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 154..426
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 504..717
FT /note="ABC transmembrane type-2 1"
FT DOMAIN 846..1098
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 1171..1385
FT /note="ABC transmembrane type-2 2"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 187..194
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 891..898
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 1444 AA; 162855 MW; AEFCD861B2DE7A88 CRC64;
MDIVRMGSVA SGGGSVRRTA SSWRGTSGRS DAFGRSVREE DDEEALKWAA IEKLPTYDRM
RKGILTAGGV EEVDIGGLGL QERRNLIERL VRTAEEDNER FLLKLRDRME RVGIDNPTIE
VRFENLSIDA EAYVGNRGIP TFTNFFSNKI MDVLSAMRIV SSGKRPISIL HDISGIIRPG
RMSLLLGPPG SGKTSLLLAL AGKLDSTLKV SGRVTYNGHD MDEFVPQRTS AYIGQHDLHI
GEMTVRETLA FSARCQGVGT RYDMLTELSR REKEASIKPD PDIDVYMKAI SVEGQESVVT
DYILKILGLE ICADTMVGDA MIRGISGGQK KRVTTGEMLV GPAKALFMDE ISTGLDSSTT
YQIVNSLRQS VHILGGTALI ALLQPAPETY DLFDDIVLLS EGQIVYQGPR ENILEFFEAM
GFKCPERKGV ADFLQEVTSR KDQHQYWCRR DEPYRYISVN DFSEAFKEFH VGRNLGSELR
VPFDRTRNHP AALTTSRYGI SKMELTKACF SREWLLMKRN SFVYIFKILQ LIILGSIGMT
VFLRTKMHRR SVEDGAIFLG AMFLGLVTHL FNGFAELAMS IAKLPIFYKQ RDLLFYPSWA
YALPTWVLKI PISFLECAVW ICMTYYVMGF DPNIERFFRH YVLLVLISQM ASGLFRLLAA
LGREMVVADT FGSFAQLILL VLGGFLISRE NIKKWWIWGY WSSPLMYAQN AIAVNEFLGH
SWNKVVDPTQ SNDTLGVQVL KVRGIFVDAN WYWIGVGALL GYIMLFNILF ILFLEWLDPL
GKGQAVVSEE ELREKHVNRT GENVELLTLG TDSQNSPSDA NAGRGEITGA DTRKRGMVLP
FTPLSITFDN IRYSVDMPQE MKDKGVTEDR LLLLKGVSGA FRPGVLTALM GVSGAGKTTL
MDVLAGRKTG GYIEGDISIS GYPKKQETFA RIAGYCEQND IHSPHVTVYE SLLYSAWLRL
PSEVDSEARK MFVEEVMELV ELTSLRGALV GLPGVNGLST EQRKRLTIAV ELVANPSIIF
MDEPTSGLDA RAAAIVMRTV RNTVDTGRTV VCTIHQPSID IFEAFDELFL MKRGGEEIYV
GPLGHNSCHL INYFEGIQGV RKIKDGYNPA TWMLEVTTLA QEDILGINFA EVYRNSDLYQ
RNKTLISELS TPPPGSTDLH FPTQFSQPFF TQCMACLWKQ HKSYWRNPSY TATRIFFTTV
IALIFGTIFL NLGKKINKRL DLFNSLGSMY AAVLFIGIQN GQTVQPIVDV ERTVFYREKA
AGMYSALPYA FAQVLIEIPH IFLQTVVYGL IVYSLIGFDW TVEKFFWYMF FMFFTFMYFT
FYGMMAVAMT PNSDIAAIVS TAFYCIWNIF AGFLIPRPRI PIWWRWYSWA CPVAWTLYGL
VASQYGDITN STLEDGEVVQ DYIRRYFGFR HDYLGYVATA VVGFAALFAF VFAFSIKVFN
FQRR
