RPOB_GEOUR
ID RPOB_GEOUR Reviewed; 1370 AA.
AC A5GAY1;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Gura_1061;
OS Geotalea uraniireducens (strain Rf4) (Geobacter uraniireducens).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC Geobacteraceae; Geotalea.
OX NCBI_TaxID=351605;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1134 / JCM 13001 / Rf4;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Shelobolina E., Aklujkar M.,
RA Lovley D., Richardson P.;
RT "Complete sequence of Geobacter uraniireducens Rf4.";
RL Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000698; ABQ25267.1; -; Genomic_DNA.
DR RefSeq; WP_011937991.1; NC_009483.1.
DR AlphaFoldDB; A5GAY1; -.
DR SMR; A5GAY1; -.
DR STRING; 351605.Gura_1061; -.
DR PRIDE; A5GAY1; -.
DR EnsemblBacteria; ABQ25267; ABQ25267; Gura_1061.
DR KEGG; gur:Gura_1061; -.
DR HOGENOM; CLU_000524_4_0_7; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000006695; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1370
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_1000086371"
SQ SEQUENCE 1370 AA; 153158 MW; E2E28D03E3750210 CRC64;
MAYSIANNPL LRKNFAKIKK IIEIPNLIDI QKNSYKRFLQ LDVPAEARKY SGLEAVFKSV
FPIKDFSETA SLEYVSYSLG IPKYDVEECH QRGMTFAAPM KVKVRLVVWD VNKEPSTRSI
RDIKEQEVYF GEIPLMTENG TFIINGTERV IVSQLHRSPG VFYDHDKGKT HSSGKVLYSA
RVIPYRGSWL DFEFDHKDIL YVRIDRRRKM PATVLLKALG YSTDKLLNFF YKSEEIFFEG
DKLMKIADPE LLTNQKAVVD IVDPNTGEVL VKANRKFTKA AIRKMAEHGI KYIPITIEEV
LGKVASHDIV DPATGEVLAE CNEELTQVKI DEIKGRGIAT FKVLFIDNLH VTSSLRDTIL
IDKIGSTDDA LIEIYRRLRP GDPPTLKSAL ALFENLFFNP ERYDLSAVGR LKLNYKLGLQ
IPLDCMTLTR EDVLEVVRYL IDLKNGKGSI DDIDHLGNRR VRAVGELLEN QYRIGLVRME
RAIKERMSLQ EVENLMPHDL INSKPVSAVV KEFFGSSQLS QFMDQTNPLS EVTHKRRLSA
LGPGGLTRER AGFEVRDVHP THYGRVCPIE TPEGPNIGLI ASLSTYARIN EHGFVETPYR
LVKEGKVTTE VRFFSALEEE GHAIAQANAE VDSDGRFVAD YISARKSGEF VLVGRDELEL
MDVAPMQLVS VAASLIPFLE NDDANRALMG SNMQRQAVPL LRADSPLVGT GMERVVARDS
GVSVVARHNG VVESVDASRI VVKIDEDEYD ETGTGVDIYN LIKFARSNQN TCINQRPVVK
IGDHVKRSDV IADGPSTDMG ELALGQNVLV AFMPWGGYNF EDSILISERL VKDDRYTSIH
IEEFECVARD TKLGKEEITA DIPNLGEETL KDLDESGIIR IGAEVRPGDI LIGKITPKGE
TQLSPEEKLL RAIFGEKAGD VRDTSLRVPP GVEGTVIGAK IFSRKGADKD ARTELIEKAE
EQKLRKDEQD EIRIIRESAV GKLKKLLVGK TAAVKFEGKD GKVLIVKGKA ITEEALLSVP
VDRWDEISIA DDDTVDEKVA QILGTLNQQI DIIKYVFDDK IQKLKRGDDL PPGVIKMVKV
YIAIKRKLQV GDKMAGRHGN KGVVSRILPE EDMPYLEDGR PVEIVLNPLG VPSRMNVGQI
LETHLGWAAK GIGWQIEDML EKNSPQNQIK TYLKEVYGNK EMNKFLDSLE EEELNNVAKR
LKRGVPMASP VFEGASEQGI QEMLGKAGFE YTGQVTLYDG KSGVAFKHKV TVGIMYVLKL
HHLVDDKIHA RSIGPYSLVT QQPLGGKAQF GGQRLGEMEV WAMEAYGAAY ALQEFLTVKS
DDVAGRTRMY EAIVKGKHTL EPGLPESFNV LIKELQSLGL DVELLENEEE