位置:首页 > 蛋白库 > RPOB_HAES1
RPOB_HAES1
ID   RPOB_HAES1              Reviewed;        1342 AA.
AC   Q0I5B7;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=HS_1565;
OS   Haemophilus somnus (strain 129Pt) (Histophilus somni).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Histophilus.
OX   NCBI_TaxID=205914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=129Pt;
RX   PubMed=17172329; DOI=10.1128/jb.01422-06;
RA   Challacombe J.F., Duncan A.J., Brettin T.S., Bruce D., Chertkov O.,
RA   Detter J.C., Han C.S., Misra M., Richardson P., Tapia R., Thayer N.,
RA   Xie G., Inzana T.J.;
RT   "Complete genome sequence of Haemophilus somnus (Histophilus somni) strain
RT   129Pt and comparison to Haemophilus ducreyi 35000HP and Haemophilus
RT   influenzae Rd.";
RL   J. Bacteriol. 189:1890-1898(2007).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000436; ABI25833.1; -; Genomic_DNA.
DR   RefSeq; WP_011609711.1; NC_008309.1.
DR   AlphaFoldDB; Q0I5B7; -.
DR   SMR; Q0I5B7; -.
DR   STRING; 205914.HS_1565; -.
DR   PRIDE; Q0I5B7; -.
DR   EnsemblBacteria; ABI25833; ABI25833; HS_1565.
DR   KEGG; hso:HS_1565; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_0_6; -.
DR   OMA; FMTWEGY; -.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 2.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 2.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW   Transferase.
FT   CHAIN           1..1342
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000300324"
SQ   SEQUENCE   1342 AA;  149894 MW;  980A55CD6261E0B6 CRC64;
     MVYSYTEKKR IRKSFGKRPQ VLNVPYLLTI QLDSFDKFIQ RDPDGQQGLE AAFRSIFPIV
     SNNGNTELQY VSYQLGEPVF DVRECQIRGT TYAASLRVKL RLVSYDKDAA SGTIKDIKEQ
     EVYMGEIPLM TSNGTFVING TERVVVSQLH RSPGVFFDSD KGKTHSSGKV LYNARIIPYR
     GSWLDFEFDP KDNLYARIDR RRKLPATIIL RALNYTTEEI LDLFFDKVSF EIKDNKLLMT
     LVPERLRGET ASFDIEANGK VYIERGRRIT ARHIKALEKD KITQVEVPTE YIVGKVSAKD
     YVDLTTGEII CPANMEISLE LLEKLSQAGY KNIETLFTND LDFGPYISET LRVDPSYDRL
     SALVEIYRMM RPGEPPTKEA AEGLFDNLFF SSERYDLSAV GRMKFNRSLG IEDTTGSGTL
     SKEDIVNVMR KLIDIRNGRG EVDDIDHLGN RRIRSVGEMA ENQFRIGLVR VERAVKERLS
     LGDLESVTPQ DLINAKPISA AVKEFFGSSQ LSQFMDQNNP LSEVTHKRRI SALGPGGLTR
     ERAGFEVRDV HATHYGRVCP IETPEGPNIG LINSLSVYAR TNDYGFLETP YRKVVNGQVT
     EEIEYLSAIE EGKYVIAQAN SNLDGELRFT DAFVTCRGEH GESGLYRPEE IHYMDVSTQQ
     VVSVAAALIP FLEHDDANRA LMGANMQRQA VPTLRADKPL VGTGMEKPVA LDSGVAVVAK
     RGGTIQYVDA SRIVVKVNED ETIAGEAGID IYNLIKYTRS NQNTCINQIP CVQLGEPIER
     GEILADGPST DLGELALGQN MRVAFMPWNG YNFEDSMLVS ERVVQEDRFT TIHIQELSCV
     ARDTKLGSEE ITADIPNVGE AALSKLDESG IVYIGAEVKG GDILVGKVTP KGETQLTPEE
     KLLRAIFGEK ASDVKDSSLR VPNGTSGTVI DVQVFTRDGV EKDKRALEIE EMQLKQAKKD
     LVEELEILEA GLFARVRNLL LSGGFNDKQL ENLDRTQWLE QTLVDEDKQN QLEQLAEQYE
     ELRKDFEHKL EIKRSKIIQG DDLAPGVLKV VKVYLAVKRQ IQPGDKMAGR HGNKGVISKI
     NPVEDMPYDE NGQPVDIVLN PLGVPSRMNI GQILETHLGL AAKGIGDQIN AMIKQKQDVE
     KLRGYIQKAY DLGDGSQKVD LSTFTDEEVL RLAKNLRKGM PLATPVFDGA HEKEIKALLE
     LGGLPTSGQI TLFDGRTGEK FERPVTVGYM YMLKLNHLVD DKMHARSTGS YSLVTQQPLG
     GKAQFGGQRF GEMEVWALEA YGAAYTLQEM LTVKSDDVNG RTKMYKNIVG GTHQMDPGTP
     ESFNVIMKEI RSLGINIDLD EE
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024