RPOB_HAHCH
ID RPOB_HAHCH Reviewed; 1357 AA.
AC Q2S905;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=HCH_06224;
OS Hahella chejuensis (strain KCTC 2396).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC Hahellaceae; Hahella.
OX NCBI_TaxID=349521;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 2396;
RX PubMed=16352867; DOI=10.1093/nar/gki1016;
RA Jeong H., Yim J.H., Lee C., Choi S.-H., Park Y.K., Yoon S.H., Hur C.-G.,
RA Kang H.-Y., Kim D., Lee H.H., Park K.H., Park S.-H., Park H.-S., Lee H.K.,
RA Oh T.K., Kim J.F.;
RT "Genomic blueprint of Hahella chejuensis, a marine microbe producing an
RT algicidal agent.";
RL Nucleic Acids Res. 33:7066-7073(2005).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000155; ABC32869.1; -; Genomic_DNA.
DR RefSeq; WP_011399927.1; NC_007645.1.
DR AlphaFoldDB; Q2S905; -.
DR SMR; Q2S905; -.
DR STRING; 349521.HCH_06224; -.
DR PRIDE; Q2S905; -.
DR EnsemblBacteria; ABC32869; ABC32869; HCH_06224.
DR KEGG; hch:HCH_06224; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_3_6; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000000238; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1357
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000237302"
SQ SEQUENCE 1357 AA; 151520 MW; 693A0AF79815BC90 CRC64;
MTYSYTEKKR IRKDFGKLPA VMDVPYLLSI QLDSYHDFLQ QDVAIEDRQE VGLHAAFKSV
FPIVSFSGNA ALEYVSYRLG QPVFDVAECQ LRGVTYAAPL RVKVRLIIYD KESSTKAIKD
IKEQEVYMGE VPLMTENGTF VINGTERVIV SQLHRSPGVF FDHDKGKTHS SGKLLYSARI
IPYRGSWLDF EFDPKDCVFV RIDRRRKLPA TILLRALGYA ADEMLEMFFE NSLFEVEGGE
YFLDLVPSRL RGDIAIFEIK DDEGNLIVEE GRRVTARHIR QMEKAGLKRL RVPSSYLLGK
VTATNIADPS TGEVIVECNT EITDDAIEKI EKAGIKRIET LYTNDLDCGP FVSDTLRIDA
TRSQLEALVE IYRMMRPGEP PTKESAENLF NNLFFSEERY DLSAVGRMKF NRRLGREETE
GLGVLSHSDI IDVLRTLIDI RNGKGVVDDI DHLGNRRVRS VGEMAENQFR VGLVRVERAV
KERLSMAESE GLMPQDLINA KPVAAAVKEF FGSSQLSQFM DQNNPLSEVT HKRRVSALGP
GGLTRERAGF EVRDVHPTHY GRVCPIETPE GPNIGLINSL ATYARTNTYG FLESPYRKVV
DGLVTDDIEY LSAIEESDYV IAQASAAVDE NGRLIDELVT VRHKNEFTVM PPEKVTLMDV
SPRQVVSVAA SLIPFLEHDD ANRALMGSNM QRQAVPTLKA EKPLVGTGME RYVAQDSGVC
VVARRGGVVV SVDAARIVVR VSDDETEAGD AGVDIYNLTK YQRSNQNTCI NQRSLVMEGD
EVARGDVLAD GPSVDLGELA LGQNMRIAFM PWNGYNFEDS ILVSERVVQE DRFTTIHIQE
LTCVARDTKL GPEEVTADIP NVGESALAKL DDSGIIYIGA EVEPGDILVG KVTPKGETQL
TPEEKLLRAI FGEKASDVKD TSLRVSTGMR GTVIDVQVFT RDGVEKDQRA KEIEQTELNK
FRKDLNDEYK IVEGATFERL RSALLGQSVI GGPGLKKGDT LTEVHFNAFE KEEWFKLNMA
DEQLNELLEK AEGQLQERRK SIEDRYEDKK RKLQSGDDLA PGVLKIVKVY VAVKRRIQPG
DKMAGRHGNK GVISAIKPVE DMPYDEQGNP VDIVLNPLGV PSRMNVGQVL ETHLGAAAKG
LGDKINRMLA EQKQAAEIRK FLHEIYNGIG GRNEDLDSLS DSEVLVLAAN LKKGVPMATP
VFDGAKEKEI KEMLRLADMD DSGQVWLYDG RTGERFERQV TVGYMYMLKL NHLVDDKMHA
RSTGSYSLVT QQPLGGKAQF GGQRFGEMEV WALEAYGAAY TLQEMLTVKS DDVNGRTKMY
KNIVDGDHRM EPGMPESFNV LVKEIRSLGI DIELEAN
