RPOB_HALHL
ID RPOB_HALHL Reviewed; 1381 AA.
AC A1WVC9;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Hhal_0865;
OS Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira
OS halophila (strain DSM 244 / SL1)).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Halorhodospira.
OX NCBI_TaxID=349124;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 244 / SL1;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Saunders E., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Hoff W.,
RA Richardson P.;
RT "Complete sequence of Halorhodospira halophila SL1.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000544; ABM61641.1; -; Genomic_DNA.
DR RefSeq; WP_011813664.1; NC_008789.1.
DR AlphaFoldDB; A1WVC9; -.
DR SMR; A1WVC9; -.
DR STRING; 349124.Hhal_0865; -.
DR PRIDE; A1WVC9; -.
DR EnsemblBacteria; ABM61641; ABM61641; Hhal_0865.
DR KEGG; hha:Hhal_0865; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_3_6; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000000647; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1381
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000300325"
SQ SEQUENCE 1381 AA; 153692 MW; 5B0246317AD4F934 CRC64;
MAYSFTEKKR IRKDFGKLPN ILDVPYLLAT QVDSYRQFLQ DEVSEDARDT EVGLEGAFRS
VFPIQSHSGN AELQYVSYRI GDPPFEVKEC QSRGLTYAAP LRMLVRLALY DKEGGGVKDI
KEQEVYMGEM PLMTSTGTFV VNGTERVIVN QLHRSPGVFF DHDKGKSHSS GKLLFSARVI
PYRGSWLDFE FDPKDTIYVR IDRRRKLPAT ILLRALGYTP EEILYAFFDT DRFHLGSGNK
VVLDLVPERL RGETASFDIV AGGETIVEAG RRVTARHVKQ LQKSGVEQLE VPEDYLTGKI
IAHDVIDPAT GEILAEANTT LTPEITQSLF DAGIREIETL FVNDLDRGPY MSTTLAADAT
RSQMEALVEI YRMMRPGEPP TKDAAENLFH TLFFTSDRYD LSPVGRMKFN LRVGRDEVRG
PGILYDGKYF AGLGNADKEA DDLIEQYGES SDILDVLREL IDIRNGNGQV DDIDHLGNRR
VRSVGEMAEN VFRVGLVRVE RAVKERLSLA ESEGLMPQEL INAKPVAAAI KEFFGSSQLS
QFMDQNNPLS EVTHKRRISA LGPGGLTRER AGFEVRDVHP THYGRVCPIE TPEGPNIGLI
NSLAVYARAN RYGFLETAYR KVVDGQVTDQ VEYLSAIEES RYVIAQANAR VDESGYLADD
LISCRHQNEF TMATADRVQY MDVSPRQIVS VAASLVPFLE HDDANRALMG ANMQRQAVPT
LRADKPLVGT GMERTVARDS GVIVTAERGG VVEQVDSGRI VVRVDDEETT PGEPGVDIYS
LTKYTRSNQN TCFSQKPLVH VGDRVARGDA LADGPSTDMG ELALGQNMLV AFMPWNGYNF
EDSILISEKL VKEDRYTSVH IEELTCVARD TKLGSEEITS DIPNVSESAL SRLDESGIVY
IGAEVKAGDI LVGKVTPKGE TQLTPEEKLL RAIFGEKASD VKDTSLRVPT GMDGTVIDVQ
VFTRDGVEKD ERARAIEREE IARVRKDLDD EARIFEDDAY ARLEKLLVGK VAEGGPKGLG
SGAEVTEAYL QDLPRERWFE IRMRDEAVNQ QLEAVRHQLE TQRDRFERRF QEKKEKITAG
DDLSPGVLKT VKVHLAVKRR LQPGDKFAGR HGNKGVISMI VPEEDMPYMD DGTPVEVVLS
PLGVPSRMNV GQVLETHLGW AARGLGHQIG QMLEQQADAE ALRGYLSEIY DASGRKEELE
TLSEEELQEL CHNLKGGVPA ATPVFDGANE GEIKRWLKLA GLPESGQTTL YDGRTGDAFD
RPITVGYMYM LKLNHLVDDK VHARATGPYS LVTQQPLGGK AQFGGQRFGE MEVWALEAYG
AAYTLQEMLT VKSDDVSGRT KMYKNIVDGD HRMEAGMPES FNVLVKEIRS LGINIELERD
D
