RPOB_HERA2
ID RPOB_HERA2 Reviewed; 1217 AA.
AC A9B6J3;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Haur_0244;
OS Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95).
OC Bacteria; Chloroflexi; Chloroflexia; Herpetosiphonales; Herpetosiphonaceae;
OC Herpetosiphon.
OX NCBI_TaxID=316274;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23779 / DSM 785 / 114-95;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C.,
RA Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA Bryant D.A., Richardson P.;
RT "Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000875; ABX02896.1; -; Genomic_DNA.
DR AlphaFoldDB; A9B6J3; -.
DR SMR; A9B6J3; -.
DR STRING; 316274.Haur_0244; -.
DR EnsemblBacteria; ABX02896; ABX02896; Haur_0244.
DR KEGG; hau:Haur_0244; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_1_0; -.
DR OMA; FMTWEGY; -.
DR Proteomes; UP000000787; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 2.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 1.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1217
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_1000141702"
SQ SEQUENCE 1217 AA; 135539 MW; BD7775738547848D CRC64;
MPQVQSTVIL PPLITSSIFR DDQGRAMIAS RRSFARITDA IELPKLIETQ IDSFRWFQRE
GLRELFDEIN PIDDFTGKNL ELSFSDYEFG EPRYNEFECR ERDMTYAAPL RVRVRLKVKT
TGEIKESDIF LGDFPLMTNN GTFVINGAER VVVSQLIRSP GVYFKEEKEP TSGRSLHSAK
LIPNRGAWLE FETNKRDVLS VKVDRKRKLP VTILIRAVLG LFGDKPLDQC GLNEDVIALF
ANVDVNRDHQ YIASTLDKDP STNAKEAIME LYKRLRPGDP ATVDNARSLL ETLLFNARRY
DLGKVGRYKL NRNLWEKSRL FEGQEIPSLT MRVLSKADLF KIVERLIDLN NGIGNPDDID
HLGNRRVRTV GELIQTQFRV GLLRMERVIK ERMSLQEPEA ATPNGLINIR PVVAAMREFF
GGSQLSQFMD QTNPLAELTH KRRLSALGPG GLSRDRAGFE VRDVHHSHYG RICPVETPEG
PNIGLIGTMS TFARVNEMGF LETPYRRVYR EVDNAPLWLE RGMTTRDVRH LSTGELIARA
GARVDAELAK IIAIGVLNGQ LLREDIVNPA TGDLIAEAGS EIDRALATKI ADLPLRAIKI
HPVVTNETDY LPADEEDKFI IAQANALLDE RFRFIDPTVS CRHAEDFVQA PIASVDYMDV
SPKQVVSVST ALIPFLEHDD ANRALMGSNM QRQAVPLLRP DAPIIGTGME HKAARDSGQV
VVARADAVVL SSNSERILVR ENDGTERTYP LLKFLRSNQD TCINQRPSVF IGDKIRAGEV
IADSSSTQNG ELALGQNILV AYMPWEGGNF EDAILVSERL VREDIFTSIH IEKYEVEARD
TKLGPEEITR DIPNVGQDSL KNLDERGIIY VGADVQPNDI LVGKITPKGE TDLTAEERLL
RAIFGEKARE VKDSSLRVPN GVKGKVIDVK VFTRDETTEM PVGVNQTVRV MLCQKRKISP
GDKMAGRHGN KGVVSRVLPI EDMPFLPDGT PVDIVLNPLA VPSRMNIGQI LETHLGWAAS
RLGFRIATPV FDGARDEDII KALAESGLPS DAKIDLYDGR TGEKFDNPVT VGYKYMLKLA
HLVEDKIHAR STGPYSLVTQ QPLGGKAQFG GQRFGEMEVW ALEAYGAAYI LQEMLTVKSD
DVVGRVKTYE AIVKGDPINE AGVPESFKVL IKELQSLGLS VDVLTADERP VELTDSEADD
LISLDGINLS GMEKGEL
