ID   RPOB_MYCPR              Reviewed;         101 AA.
AC   Q9RQZ7;
DT   10-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta;
DE            Short=RNAP subunit beta;
DE            EC=2.7.7.6;
DE   AltName: Full=RNA polymerase subunit beta;
DE   AltName: Full=Transcriptase subunit beta;
DE   Flags: Fragment;
GN   Name=rpoB;
OS   Mycolicibacterium peregrinum (Mycobacterium peregrinum).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=43304;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 14467 / DSM 43271 / JCM 12142 / NCTC 10264 / TMC 1547;
RX   PubMed=10325313; DOI=10.1128/jcm.37.6.1714-1720.1999;
RA   Kim B.J., Lee S.H., Lyu M.A., Kim S.J., Bai G.H., Chae G.T., Kim E.C.,
RA   Cha C.Y., Kook Y.H.;
RT   "Identification of mycobacterial species by comparative sequence analysis
RT   of the RNA polymerase gene (rpoB).";
RL   J. Clin. Microbiol. 37:1714-1720(1999).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6;
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000305}.
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DR   EMBL; AF057481; AAD55545.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9RQZ7; -.
DR   SMR; Q9RQZ7; -.
DR   STRING; 43304.GCA_001403655_00494; -.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW   Transferase.
FT   CHAIN           <1..>101
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000047923"
FT   REGION          74..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT   NON_TER         101
SQ   SEQUENCE   101 AA;  11305 MW;  0EFD205E519E7E91 CRC64;
     RTVGELIQNQ IRVGLSRMER VVRERMTTQD VEAITPQTLI NIRPVVAAIK EFFGTSQLSQ
     FMDQNNPLSG LTHKRRLSAL GPGGLSRERA GLEVRDVHSS H