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RPOB_NITEU
ID   RPOB_NITEU              Reviewed;        1357 AA.
AC   Q82T75;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=NE2046;
OS   Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC
OS   14298).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=228410;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298;
RX   PubMed=12700255; DOI=10.1128/jb.185.9.2759-2773.2003;
RA   Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L.,
RA   Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A.,
RA   Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.;
RT   "Complete genome sequence of the ammonia-oxidizing bacterium and obligate
RT   chemolithoautotroph Nitrosomonas europaea.";
RL   J. Bacteriol. 185:2759-2773(2003).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR   EMBL; AL954747; CAD85957.1; -; Genomic_DNA.
DR   RefSeq; WP_011112559.1; NC_004757.1.
DR   AlphaFoldDB; Q82T75; -.
DR   SMR; Q82T75; -.
DR   STRING; 228410.NE2046; -.
DR   PRIDE; Q82T75; -.
DR   EnsemblBacteria; CAD85957; CAD85957; NE2046.
DR   KEGG; neu:NE2046; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_1_4; -.
DR   OMA; FMTWEGY; -.
DR   OrthoDB; 9601at2; -.
DR   PhylomeDB; Q82T75; -.
DR   Proteomes; UP000001416; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 1.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..1357
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000047931"
SQ   SEQUENCE   1357 AA;  151796 MW;  F20CEECB12A09A79 CRC64;
     MSYSFAEKKR IRKSFAKRAS ILPFPFLLAT QIQSYTDFLQ AEIAPGKRKN QGLQAAFNSV
     FPIESHSNNA RLDFISYMLG SPVFDVKECQ QRGLTYAAPL RARVRLTILD KEASKPTVKE
     VKEQEVYMGE IPLMTDTGSF VVNGTERVIV SQLHRSPGVF FEHDRGKTHS SGKLLFSARI
     IPYRGSWLDF EFDPKDYVYF RIDRRRKMPV TTLLKAMGYS PAQILADFFE FDHFILVDNK
     IFFNLIPERL RGELAGFDIV SEDGKVFVQK DKRITAKHVR DLQQANLTKI PVPEEFLLGK
     ILAADLVDKE TGEIIALANS EISETLLGRI RQTQSSEIST LFVNDLNYGP YISQTLRIDE
     TTDQMSAQVA IYRMMRPGEP PTEEAVLALF NGLFYSPERY DLSVVGRMKF NRRVGREELT
     GSTTLSNDDI IDVIKILVEL RNGRGEIDDI DHLGNRRVRS VGELAENQFR AGLARVEKAV
     KERLSQAESE NLMPHDFINA KPVSSAIREF FGSSQLSQFM DQTNPLSEVT HKRRISALGP
     GGLTRERAGF EVRDVHPTHY GRVCPIETPE GPNIGLINSL ALYARTNEYG FIETPYRMVR
     NGRVTEEVVY LSAIEESQYV IAQANANFDQ NGVFTDEVVS CRHKNEFTLA SRDQIEYVDI
     APAQIVSVAA SLIPFLEHDD ANRALMGSNM QRQAVPCLRA EKPLVGTGIE RVVAVHSGTA
     VRTIRGGVVD YVDASRIVIR VHDAEARAGE VGVDIYNLTK YTRSNQNTNI NQRPIVRMGD
     VLSRDDVIAD GASTDLGELA LGQNMLIAFM PWNGLNFEDS ILISERVVSD DRFTSIHIEE
     LAAVSRDTKL GTEEITADIP NLSERQRARL DESGIVYIGA EVEAGDVLVG KVTPKSETQL
     TPEEKLLRAI FGEKASDVKD TSLHVPAGIS GTVIDVQIFT REGVDRDKRS KQIIADELGR
     FKKDLADQMR IVEADAFQRA ERLLTGKVAA GGPKKLAKNS TITRDYLENV EKHHWFDIRL
     VDENTSLQLE QIKDSLVQKR KLFDLAFEEK HRKLSQGDEL PPGVQKMVKV YIAVKRRLQS
     GDKMAGRHGN KGVISKIVPI EDMPYMADGT PVDVVLNPLG VPSRMNIGQV LEVHLGWAAK
     ELGKRVNEML ASQRNVSDIR DFLNKIYNNS GKQEDLTSLE DDEVLALARN LSSGVPFATP
     VFDGAHESEI KQMLKLAGLP ESGQTTLYDG RTGEAFDRPV TVGYMHVLKL HHLVDDKMHA
     RSTGPYSLVT QQPLGGKAQF GGQRFGEMEV WALEAYGASY TLQEMLTVKS DDVNGRTKVY
     ESIVKGDHKI DAGMPESFNV LVKEIRSLGL DIDLEEH
 
 
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