RPOB_NITOC
ID RPOB_NITOC Reviewed; 1359 AA.
AC Q3J8Q7;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Noc_2331;
OS Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB
OS 11848 / C-107).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Nitrosococcus.
OX NCBI_TaxID=323261;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107;
RX PubMed=16957257; DOI=10.1128/aem.00463-06;
RA Klotz M.G., Arp D.J., Chain P.S.G., El-Sheikh A.F., Hauser L.J.,
RA Hommes N.G., Larimer F.W., Malfatti S.A., Norton J.M., Poret-Peterson A.T.,
RA Vergez L.M., Ward B.B.;
RT "Complete genome sequence of the marine, chemolithoautotrophic, ammonia-
RT oxidizing bacterium Nitrosococcus oceani ATCC 19707.";
RL Appl. Environ. Microbiol. 72:6299-6315(2006).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000127; ABA58789.1; -; Genomic_DNA.
DR RefSeq; WP_002808701.1; NC_007484.1.
DR AlphaFoldDB; Q3J8Q7; -.
DR SMR; Q3J8Q7; -.
DR STRING; 323261.Noc_2331; -.
DR EnsemblBacteria; ABA58789; ABA58789; Noc_2331.
DR KEGG; noc:Noc_2331; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_0_6; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000006838; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 2.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 2.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1359
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000224083"
SQ SEQUENCE 1359 AA; 151136 MW; D9A76ABFB372C35C CRC64;
MPYSLTEKKR IRKDFSKLHS ILKTPFLLTI QIGSFLDFLQ MDVPPGKRKD KGLHAAFKSV
FPIKSYTEYA ELQYSSYHLG VPSFEVKECQ VRGLTYAAPL RVKLRLVIYD KESPASEQVV
KDVKEQEVYM GEIPLMTPKG NFVINGTERV IVSQLHRSPG VIFEHDKGKT HSSGKLLFSA
RIIPYRGSWL DFEFDPKDCV YARIDRRRKL LATILLRALG YSTEEILIMF FETISVKRQG
SSYLLDLVPQ RLRGESLPFD IASPDGEVIV EAGRRVTARH IKQMEKAGMK TLPAPKEFLI
GKTLARDLID AGTGEVLAKA NDEITAELMT ALEDANIQAF DLIYTNDLDR GSFISDSLRL
DPTTTPLEAQ MEIYRVMRPG EPPTKEAAQN LFQNLFFNPE RYDLSPVGRM KFNRRLGKED
ITGPSILSKE DIVDVIKTLV DIRNGYGSVD DVDHLGNRRV RSVGEMAENQ FRVGLVRVER
AVRERLSLAE SEGLMPQELI NAKPVSAAVK EFFGSSQLSQ FMDQNNPLSE VTHKRRVSAL
GPGGLTRERA GFEVRDVHPT HYGRVCPIET PEGPNIGLIN SLAVYARINQ YGFIETPYRK
VVDGKVAGEV DYLSAIEEGQ YVIAQANAAA DEEGRLIDML VSCRHKNEFT LLPPEKVQYI
DVSPKQIVSV AASLIPFLEH DDANRALMGS NMQRQAVPTL RAETPLVGTG MEQVVARDSG
VMVVARRGGI VDSVDAARVV VRVNDEETAS DEPGVDIYNL IKYARSNQNT CINQSPLVKP
GDTVAIGDVL ADGPSTDMGE LALGQNLLVA FMPWNGYNFE DSILISERVV EEDRFTSIHI
EELTCFARDT KLGPEEISSD IPNVSEAALS KLDEAGIVYI GAEVKPGDIL VGKVTPKGET
QLTPEEKLLR AIFGEKASDV KDTSLRVSSG MQGTVIDVQV FTRDGVEKDT RALEIEEMEL
AKIKKDLRDE FRIVETDIYQ RLEKVLVGKT VEGGPAELKA GTQITQNYLA DLPRERWFEI
RLRSEEAGRQ LESVAGQLKE QRVAMDEKFQ QQRAKLTSGH DLPPGVQKMV KVYLAVKRRV
QPGDKMAGRH GNKGVISTIV PIEDMPYMED GTPVDIVLNP LGVPSRMNIG QILETHLGWA
AKGLGRKIGA LLESGEQASE LRVFLDRIYN ASGKKEDLNS LSDEEVLELA NNLKDGVPMA
TPVFDGASEQ EIKTMLELAD LPTNGQTNLY DGRSGEAFAR PVTVGYMHML KLNHLVDDKM
HARSTGPYSL VTQQPLGGKA QFGGQRFGEM EVWALESYGA AYTLQEMLTV KSDDVNGRTK
MYKNIVDGDY RMEAGMPESF NVLTKEIRAL GIDIELEQD
