ID   RPOB_NPVOP              Reviewed;         884 AA.
AC   O12934;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Probable DNA-directed RNA polymerase subunit beta;
DE            EC=2.7.7.6;
DE   AltName: Full=Late expression factor 8;
GN   Name=LEF-8; ORFNames=ORF54;
OS   Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX   NCBI_TaxID=262177;
OH   NCBI_TaxID=33414; Orgyia pseudotsugata (Douglas-fir tussock moth).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9126251; DOI=10.1006/viro.1997.8448;
RA   Ahrens C.H., Russell R.R., Funk C.J., Evans J., Harwood S., Rohrmann G.F.;
RT   "The sequence of the Orgyia pseudotsugata multinucleocapsid nuclear
RT   polyhedrosis virus genome.";
RL   Virology 229:381-399(1997).
CC   -!- FUNCTION: Required for late and very late gene expression. May be a
CC       component of the novel RNA polymerase activity induced by baculovirus
CC       infection.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6;
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U75930; AAC59053.1; -; Genomic_DNA.
DR   RefSeq; NP_046210.1; NC_001875.2.
DR   GeneID; 912113; -.
DR   KEGG; vg:912113; -.
DR   Proteomes; UP000009248; Genome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 2.40.270.10; -; 1.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR007025; LEF-8.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   Pfam; PF04941; LEF-8; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW   Transferase.
FT   CHAIN           1..884
FT                   /note="Probable DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000048054"
SQ   SEQUENCE   884 AA;  100357 MW;  8446DE801CFB2D1D CRC64;
     MTDVVRDFDA LYAKLEAPPH NLRLVLECCA PESGPLDLAA IQERKSYTCC ALNNRRNCVL
     HKCVVVVFGT ALDARLRAPS AEFDAQNNLR GTFMLDGRFL SFPNIMMNNN VLMHNFYDKL
     YAKHCKRMFL YGNVDAEKHI NRAIQLVYDK ATRRLFARDV YASDYVVTDD LNAVLETYLA
     SSGKWRPLDH LFRYSKAHKQ QLVDHIKMIM HHDICYSIDN LANKIIYKHA YLMELLLTST
     VLQHYQKRAG ENEALKRRLE CEGEPPASKR RKAQSVLYGK ESKKIVDSVV NGRLIYCVSK
     TFSKQRRSFP NQHDNCSNNN IEISLPVLKY RVGSEVTRIT NDSVRQKMLK QKKDFVKFIG
     SFFHGEMTVA GKKFFLCRNA RLPNVDYAMV ADKFAELQQF GLVAPVHDLA HCADGALLIA
     FNDRPTNLQC ARADVPKIVY RLKRDRCPIE LKASSNILYV NHHEGMVCIA KRVRIGAPVN
     ASINALLTPY EYHYKNSLFH APTVSACEIE ESDDVRCLMS KLEQYYFAEY THLFYTIPVP
     KMIVALTNLK NAMPVLRYST LGTAPVGLSV AVGDHVLMNN KMVKLWTLVR DSKLMTAEDP
     YIPHMALPIR LYNHKVNKLK GKLALAGKAV PTLKFVASSG PHNCVVLPDN MVQYFAGTVL
     SGAKIVWAHD GKRCMVEACT NGAHNVYKVY VFFRRTRNQA VESLAASMTL AGDAVIVRTA
     VVTSTDDLEG VKVCSVHGQK GVLNRSEDLT EWMAEDGTHA QICLSPVSYL SRQSNFERLE
     RKYVVRGGNH ADPRARRYPI FNIPYMLFNN TPDNIYKEFN KKNYTGHEKV EGTRFDQWTK
     NQSFVGNRLA ESLQWMRGGS NLPQNCGEFE VVSSLLMCNN VVMK