ID   RPOB_NPVSL              Reviewed;         909 AA.
AC   O57030;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Probable DNA-directed RNA polymerase subunit beta;
DE            EC=2.7.7.6;
DE   AltName: Full=Late expression factor 8;
GN   Name=LEF-8;
OS   Spodoptera littoralis nuclear polyhedrosis virus (SlNPV).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX   NCBI_TaxID=10456;
OH   NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Isolate E15;
RX   PubMed=9354263; DOI=10.1023/a:1007942510506;
RA   Faktor O., Kamesnky B.;
RT   "Genomic localization and nucleotide sequence of a lef-8-like gene of the
RT   Spodoptera littoralis nucleopolyhedrovirus.";
RL   Virus Genes 15:9-15(1997).
CC   -!- FUNCTION: Required for late and very late gene expression. May be a
CC       component of the novel RNA polymerase activity induced by baculovirus
CC       infection.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6;
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000305}.
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DR   EMBL; Y10669; CAA71676.1; -; Genomic_DNA.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 2.40.270.10; -; 1.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR007025; LEF-8.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   Pfam; PF04941; LEF-8; 2.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW   Transferase.
FT   CHAIN           1..909
FT                   /note="Probable DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000048055"
SQ   SEQUENCE   909 AA;  104944 MW;  12B4A49BFFD78C9A CRC64;
     MTDVVSDFDH VYNIIRNNYN LNYYLNCADR SNNVCTIKYL QERKSYFCCA VDESTGRCVL
     HRCVLIVFGT WLDKKFRKKE FSGGDATCGG GGGDGDQDQD AIDERSNIKG TFMIDGRFLS
     FPNVMMNNNI LMHNFYDKLY SKNCKRMFLY GNVDEEKRIN RAIQLVYDDH EDVLFARDVY
     AKDYVVSENL NETLETYLRS SGKWEPLNFL FDFDKNQTDK MFDRIKMIMR AEINYSIDSL
     SNKIIYKHAY LTHLLYRPVL KMYQASKIDS AAAVSESNGS LRKLGGNQSG AMYPKDCKKI
     VDTIVNGKLI HVISKTFSKQ KKNFLNHQDN SSNNNIEMCP PMIKYRVGNE VVRIINDNMR
     QDMLKQEYDF VKFVDSFFHG EMTVAGKKFF LCRDVRLPNV DYESIAKKFK DLIESNLIVR
     RDEDENGSGG DDDDDEWLMI AFNNRPTTFS CKRKHLVRIV YEFKRKRFPV EIKLSKSILF
     VNHHEGMICI RKQVRINEKV NISALLTPYE YHNVESIIGQ IGARIVDVDH VSALMSKTLQ
     YYYRSHLHIF ATIPVPKLIV SVTNLKNAMP VIEYDDVEWN ENRDMFIRNL PVGNSVVASP
     GSVHNNKMIN LWTLVRDSRL MTAEDPYIPN VTLPVKLFNN KVNRLKGKMV YASKSKTPLV
     KFFKSESNNF VDTNEGHVLA MAGVIVSNVK INWTHDGKRY KIETCKNKSF YIFKIYTFLR
     KIRSQRIELI DAKLSTLNDF VYVKFSIVTS TNNLDGIKIC GIHGQKGVMN SSEDLTEWMA
     EDGTHAQICL SPVSFLSRQS NFDYIERKYV VRGGDHTDPS AVRYPMFRIP YMLFNNTPEI
     LQRIPQTNYT GHEKIEGTRL DQWSINQSFA GNRWAEGLQC VRGGTNLPDS SGEYKVLTSL
     LHCNNVIVN