ID   RPOB_OENOB              Reviewed;        1197 AA.
AC   Q04E85;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=OEOE_1375;
OS   Oenococcus oeni (strain ATCC BAA-331 / PSU-1).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Oenococcus.
OX   NCBI_TaxID=203123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-331 / PSU-1;
RX   PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA   Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V.,
RA   Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V.,
RA   Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M.,
RA   Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A.,
RA   Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W.,
RA   Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y.,
RA   Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R.,
RA   O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T.,
RA   Richardson P., Kozyavkin S., Weimer B.C., Mills D.A.;
RT   "Comparative genomics of the lactic acid bacteria.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR   EMBL; CP000411; ABJ57237.1; -; Genomic_DNA.
DR   RefSeq; WP_011677689.1; NC_008528.1.
DR   AlphaFoldDB; Q04E85; -.
DR   SMR; Q04E85; -.
DR   STRING; 203123.OEOE_1375; -.
DR   PRIDE; Q04E85; -.
DR   EnsemblBacteria; ABJ57237; ABJ57237; OEOE_1375.
DR   KEGG; ooe:OEOE_1375; -.
DR   PATRIC; fig|203123.7.peg.1389; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_1_9; -.
DR   OMA; FMTWEGY; -.
DR   OrthoDB; 9601at2; -.
DR   Proteomes; UP000000774; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 2.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 2.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..1197
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000300361"
FT   REGION          581..603
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1172..1197
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1197 AA;  133225 MW;  1A261C6CF446C480 CRC64;
     MVTHNVKINK HVTRRSYSSA KEVLEIPPLT EVQTASYKWF MDKGIKEMFN DIMPIEDFAG
     KLSLEYVDYS LGEPKYSLKE SREQAVNYAA PLHVTLRLTN KETGEIKSQD VYFGEFPLMT
     EYGSFVINGA ERVVVSQLVR SPGIYYNEDT DKTGRVVYGT TVIPNRGAWL ELDTDAKGVA
     NIRIDRTRKL PITELIRSFG FGSDSEIQDI FGDEIDSLNL AIEKDVHKDP SMSRVGEALE
     DIYERLRPGE PKTIDSSRSL LAARFFDPKR YDLGNVGRYK VNKKLSLKSR LLGQTLAEDI
     LNSDGEVVVP KDTKIDKKSM KLISPLLDEE DFHVENLQPD EEGVLPDPIK VQTIKIFSQV
     DPTKVIKLIG NGHIDESIHH ILPADIIAGM NYFFNLQEGV GATDDIDHLG NRRIRSVGEL
     LENQFRIGLT RMERVVRERM SIQDSDTVTP QQLINIRPVV AVVKEFFGSS QLSQFMDQTN
     PLGELNHKRR LSALGPGGLT RDRAGYEVRD VHYSHYGRID PIETPEGPNI GLITSLAVYG
     RINEYGFIET PYRRVDWDTH KVTDKIDYLT ADVEDNYTIA QANSPLNDDG SFTNPTVTAR
     HGDNNIETPI EDVDYMDVSP KQVVAVSTAA IPFLENDDSN RALMGANMQR QAVPLVAPHS
     PIVGTGIEYR AAVDSGLAQI AEEKGTVEYV DGRTIKVREE DGTLHEYPLM KFQRSNGGKN
     YNQTPIVKVG EKIEKGEVLA DGPAMENGEL ALGQNPVIAF MTWHGYNFED AIVLNERLVR
     DDVYTSIHIE EHESEARDTK LGPEEITREI PNVGEDQLKD LDDSGIIRIG AEVEDGDILV
     GKITPKGVTE LSAEERLLHA IFGEKAREVR DTSLRVPHGG GGIIQDVEIF TRENGDELAP
     GVNMMVRVFI AQKRKIQVGD KMAGRHGNKG TVSVVVPEED MPFMPDGRPI DILLSPMGVP
     SRMNIGQILE LHLGMAAKKL GIKIMTPVFD GASDDEIIDA LKEAGLDEDG KTVLYDGQTG
     EAFDNRISVG VMHYMKLAHM VDDKIHARSI GPYSLVTQQP LGGKAQFGGQ RFGEMEVWAL
     EAYGAAYTLQ EILTYKSDDV RGRNKVFESI VKGQAIPKPG VPESFRVLVK ELQALGLDMK
     VLNGKGQEVK MAQMDEDDNV ATVDALEQIA KEKPDLFKGD DDDTPRIPAT KLDEENV