ID   RPOB_OLEA2              Reviewed;        1375 AA.
AC   Q30X05;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Dde_2997;
OS   Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20)
OS   (Desulfovibrio alaskensis).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfovibrionaceae; Oleidesulfovibrio.
OX   NCBI_TaxID=207559;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1058 / DSM 17464 / G20;
RX   PubMed=21685289; DOI=10.1128/jb.05400-11;
RA   Hauser L.J., Land M.L., Brown S.D., Larimer F., Keller K.L.,
RA   Rapp-Giles B.J., Price M.N., Lin M., Bruce D.C., Detter J.C., Tapia R.,
RA   Han C.S., Goodwin L.A., Cheng J.F., Pitluck S., Copeland A., Lucas S.,
RA   Nolan M., Lapidus A.L., Palumbo A.V., Wall J.D.;
RT   "Complete genome sequence and updated annotation of Desulfovibrio
RT   alaskensis G20.";
RL   J. Bacteriol. 193:4268-4269(2011).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR   EMBL; CP000112; ABB39791.1; -; Genomic_DNA.
DR   RefSeq; WP_011368764.1; NC_007519.1.
DR   AlphaFoldDB; Q30X05; -.
DR   SMR; Q30X05; -.
DR   STRING; 207559.Dde_2997; -.
DR   PRIDE; Q30X05; -.
DR   EnsemblBacteria; ABB39791; ABB39791; Dde_2997.
DR   KEGG; dde:Dde_2997; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_0_7; -.
DR   OMA; FMTWEGY; -.
DR   OrthoDB; 9601at2; -.
DR   Proteomes; UP000002710; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 1.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..1375
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000224052"
SQ   SEQUENCE   1375 AA;  154037 MW;  A74C362B17BC97E0 CRC64;
     MGQLTKKFGK IEVTLPIPHL LNLQVDSYKK FLQEGAAALA PDEGLEGVFR SVFPIEDFNR
     TASLEYVSYE IGEPKYDQAE CISKGLTYEA PIRIKVRLVV YDVDEDSENR TIRDIKEQDI
     YFGTLPLMTE KGTFIINGTE RVIVNQLQRS PGIIFEHDAG KTHSSRKVLY SCRVIPMRGS
     WLDFDYDHKD ILYVRIDRRR KMPATILFKA MGMSRSDILE YFYKKEYYTL EDDGRLMWEL
     DKDLYRKDVA YADVADGEGK VIAKAGKPYT KRSWRLMLEA GIPAVEVAPD YIAGMFLAED
     IVDEATGEVL AEAADEITLD LIDRLRECSI KRVPVLHTKG SDTSSSIRDT LLLDKTADQE
     QARVEIYRRL RPSSPPTPEI ASTFFENLFR NPDYYDLSPV GRYKLNQRLG LTTTQERVLT
     DEDILTAIRV LNHLKDTHGP ADDIDHLGNR RVRPVGELVE NQYRIGLVRM ERAIKERMSL
     QEVSTLMPHD LINPKPVQAV LKEFFGTSQL SQFMDQTNAL SEVTHKRRLS ALGPGGLTRE
     RAGFEVRDVH TSHYGRICPI ETPEGPNIGL IVSLTTYAKV NDFGFIETPY RVVRDGQVTD
     EVKYLDASSE HGEVVAQANA RLDGDHRFVD EFVTTRVRGD VIMSPREEVT LMDISPSQMV
     SISAALIPFL EHDDANRALM GSNMQRQAVP LLRSTKPIVG TGMEADVARD SGACIIAEAD
     GVVRYADADR IVVSYEGDLY PRTGGVRSYD LQKYHKSNQS SCFGQKPLVS RGQVIRKGDV
     LADGPGIEDG ELALGKNLVV AFMPWCGYNF EDSILISERC VKEDVFTSVH IEEFEVVARD
     TKLGPEEITR DIPNVGEDML RNLDGSGIIR IGANVKPDDI LVGKITPKGE TQLTPEEKLL
     RAIFGEKARD VKNTSLKVPP GIEGTVIDVK LFNRRSGEKD ERTRNIEDYE LARLDQKEKD
     HIRALTETTR EKLAPVVVGK QLAYGLAGQK KGEVIAEAGQ TLTAEMLEGL PVKKLSGLFK
     SKDTNEAVQQ ALESYDRQIE FINAMYESKR EKVTEGDDLP PGVIKMAKVH IAVKRKLNVG
     DKMAGRHGNK GVVSCILPQE DMPFFADGRP VDIVLNPLGV PSRMNIGQIM ETHLGWAAKE
     MGRKLALMLE HGQDLASVRE QVKTVFASDA ISSEVDNMDD ETFVRSVRRL RDGIVTKTPV
     FDGATEEQIW SWMEQAGLAN DGKTELYDGR TGVRFHNRVT TGVMYILKLH HLVDEKIHAR
     STGPYSLVTQ QPLGGKAQFG GQRLGEMEVW ALEAYGAAYL LQEFLTVKSD DVTGRVKMYE
     KVVKGDNFLE AGLPESFNVL VKELMSLGLD VTLHQEEGKK RTKRAGMTFG DGTSY