RPOB_ONYPE
ID RPOB_ONYPE Reviewed; 1273 AA.
AC Q6YQW3;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=PAM_260;
OS Onion yellows phytoplasma (strain OY-M).
OC Bacteria; Tenericutes; Mollicutes; Acholeplasmatales; Acholeplasmataceae;
OC Candidatus Phytoplasma; Candidatus Phytoplasma asteris.
OX NCBI_TaxID=262768;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OY-M;
RX PubMed=14661021; DOI=10.1038/ng1277;
RA Oshima K., Kakizawa S., Nishigawa H., Jung H.-Y., Wei W., Suzuki S.,
RA Arashida R., Nakata D., Miyata S., Ugaki M., Namba S.;
RT "Reductive evolution suggested from the complete genome sequence of a
RT plant-pathogenic phytoplasma.";
RL Nat. Genet. 36:27-29(2004).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP006628; BAD04345.1; -; Genomic_DNA.
DR AlphaFoldDB; Q6YQW3; -.
DR SMR; Q6YQW3; -.
DR STRING; 262768.PAM_260; -.
DR PRIDE; Q6YQW3; -.
DR EnsemblBacteria; BAD04345; BAD04345; PAM_260.
DR KEGG; poy:PAM_260; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_1_14; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR BioCyc; OYEL262768:G1G26-317-MON; -.
DR BRENDA; 2.7.7.6; 14812.
DR Proteomes; UP000002523; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 2.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 2.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1273
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000224086"
SQ SEQUENCE 1273 AA; 143378 MW; 9DDEA921A5A37F29 CRC64;
MGYHNVKYGK KAQRRNYSKT IYDVDLPNLI EIQNQSFDWF LKHGIKELLQ DFCPIESYNG
DLKIHFDDYF LAPPKYSIEE TKIKDISYVA QLFVKTTLEN VLTGETKQSN ILLTELPLMT
PTGTFVINGT ERVVVSQIVR SASVYFAGNF DSKLNRTTYS GQVIPSRGAW IEYEEGSKEI
LYAKLDRSKK IPLSNFIYAL GFDSKEAIEN VFGKSAIIDS VFDKETDMDS DNALVELYSK
IRQGEKVPVD TARDFIRTRL FDQKKYDLAK VGRYKFNKKL DVLTRAENTY LACDFVNPET
QEIIIAQDEL LTKEKIAILK QNRHFLLQEI FDAKHNLENE TDEEILAYKK DPQKNELFTK
TNIINSRTGE VLVAKDTLVN DDIINHLRHN IHTLDEKVSK FFLGTKDIYQ KEADRQGVFN
EILEVYTSKD ESGKLYHKVK LIGNDQRETK KHITLSDVIA SINYYLNLYE NVGTVDDIDH
LGNRRLRLIG ELLKNQFRIG LTRAEKNIKD MISTSKFSEV NGPGDLVNFT FLMSVIKTFF
TSSRLSQFMD QINPLAELTQ KRRVSALGIG GINRDRAGIE VRDVHNSHYG RLCPIETPEG
PSIGLITSLS TYAKVNKYGF IQTPFFKVLH QDGKTTLSRH IDYLTADQEK EEIIASAGFV
LDANNAFKDK KIIARSNGET GIFERSQITY ADVSPKQIVS VATSSIPFLE HNDASRALMG
ANMQRQAVPL LIPESPIVGT GVEYRAAKDS GCLIIARESG FVTYVDAQKI IITKKPNQNV
SLNGKTLYDT TQEFTYAQAK ALYENNYKEH QAEYTLINFA KSNQDTLVLQ KPIVVLGEQI
NEGDILVSGP STSQGELALG RNVTVAFMTW EGYNYEDAII MSEELVKHDV YTSIHIDKYE
VQTRELKKGS GQEEITREVP NVGADAIKNL DERGIIIPGS EVKEGDILVG KITPQGNIEP
SPSEKLIQIV IGEKAREYKD SSLRVPFGEG GIVQSVHYFS RKNGDVLPAG VNENIRVFIA
KKRKINEGDK MAGRHGNKGV ISRILPKEDL PYMADGTPID IMLNPLGVPS RMNIGQILEI
HLGMAAKKLG IKVATPVFDG VNDYDLKEIM KEANLDPDGK MVLYDGRTGE PYDSRISVGV
MYMVKLSHMV DDKLHARNVG PYTLVTQQPM GGKVQNGGQR FGEMEVWALY AYGAAHTLQE
ILTVKSDDIV GRNKTYSAIV QGTPLPKPSI PESFRVFIKE LQSLGLYVEL IKTDTKENEV
NKSLIDYKKE GYN
