ID   RPOB_PASMU              Reviewed;        1342 AA.
AC   Q9CK91;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=PM1737;
OS   Pasteurella multocida (strain Pm70).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Pasteurella.
OX   NCBI_TaxID=272843;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pm70;
RX   PubMed=11248100; DOI=10.1073/pnas.051634598;
RA   May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.;
RT   "Complete genomic sequence of Pasteurella multocida Pm70.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR   EMBL; AE004439; AAK03821.1; -; Genomic_DNA.
DR   RefSeq; WP_010907308.1; NC_002663.1.
DR   AlphaFoldDB; Q9CK91; -.
DR   SMR; Q9CK91; -.
DR   STRING; 747.DR93_617; -.
DR   EnsemblBacteria; AAK03821; AAK03821; PM1737.
DR   KEGG; pmu:PM1737; -.
DR   PATRIC; fig|272843.6.peg.1759; -.
DR   HOGENOM; CLU_000524_4_0_6; -.
DR   OMA; FMTWEGY; -.
DR   Proteomes; UP000000809; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.40.270.10; -; 1.
DR   Gene3D; 2.40.50.150; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..1342
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000047933"
SQ   SEQUENCE   1342 AA;  149567 MW;  1B60A6441A6C3C6C CRC64;
     MVYSYTEKKR IRKDFGKRPQ VLNVPYLLTI QLDSFDKFIQ RDPEGQQGLE AAFRSVFPIV
     SNNGNTELQY VSYQLGEPVF DVRECQIRGT TYAAPLRVKL RLVSYDKDAA PGTIKDIKEQ
     EVYMGEIPLM TDNGTFVING TERVIVSQLH RSPGVFFDSD KGKTHSSGKV LYNARIIPYR
     GSWLDFEFDP KDNLYARIDR RRKLPATIIL RALNYTTEQI LDIFFDKVVF EISNNKLLMT
     LVPERLRGET ATFDIEANGK VYVERGRRIT ARHIRALEKD QITQVEVPTE YIVGKVAAKD
     YVDLESGEIV CPANMEISLE MLAKLAQAGY KTIETLFTND LDYGPYISET LRVDPSNDRL
     SALVEIYRMM RPGEPPTKEA AEGLFDNLFF SSDRYDLSAV GRMKFNRSLG IDEETGSGIL
     SNDDIIGVMK KLIEIRNGRG EVDDIDHLGN RRIRSVGEMA ENQFRIGLVR VERAVKERLS
     LGDLDAVTPQ DLINAKPISA AVKEFFGSSQ LSQFMDQNNP LSEVTHKRRI SALGPGGLTR
     ERAGFEVRDV HATHYGRVCP IETPEGPNIG LINSLSVYAR TNDYGFLETP YRKVVNGQVT
     EEIEYLSAIE EGKYVIAQAN SNLDEELRFT DAFVTCRGEH GESGLYRPDE IHYMDVSTQQ
     VVSVAAALIP FLEHDDANRA LMGANMQRQA VPTLRADKPL VGTGIEKAVA VDSGVTVIAK
     RGGMVQYVDA SRIVVKVNED ETIPGEAGID IYNLVKYTRS NQNTCINQIP CVSLGEPIGR
     GEVLADGPST DLGELALGQN MRVAFMPWNG YNFEDSMLVS ERVVQEDRFT TIHIQELSCV
     ARDTKLGSEE ITADIPNVGE AALSKLDESG IVYIGAEVKG GDILVGKVTP KGETQLTPEE
     KLLRAIFGEK ASDVKDSSLR VPNSVSGTVI DVQVFTRDGV EKDKRALEIE EMQLKQAKKD
     LVEELEILEA GLFTRVRSLL IAGGFDAKNL DKLDRTKWLE QSLSDEAQQN QLEQLAEQYE
     ELRKEFERKL EVQRGKIIQG DDLAPGVLKV VKVYLAVKRQ IQPGDKMAGR HGNKGVISKI
     NPVEDMPYDE NGQPVDIVLN PLGVPSRMNI GQILETHLGL AAKGIGDKIN AMIKQQQDVA
     KLREYMQKAY DLGHGSQKVD LSTFSDEEVM RLAQNLRKGL PLATPVFDGA HESEIKGLLE
     LGGLPTSGQI TLFDGRTGEK FERPVTVGYM YMLKLNHLVD DKMHARSTGS YSLVTQQPLG
     GKAQFGGQRF GEMEVWALEA YGAAYTLQEM LTVKSDDVNG RTKMYKNIVG GTHQMDPGTP
     ESFNVIMKEI RSLGINIDLD ED