RPOB_PELPD
ID RPOB_PELPD Reviewed; 1499 AA.
AC A1ALT4;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Ppro_0673;
OS Pelobacter propionicus (strain DSM 2379 / NBRC 103807 / OttBd1).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC Desulfuromonadaceae; Pelobacter.
OX NCBI_TaxID=338966;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2379 / NBRC 103807 / OttBd1;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Saunders E., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Lovley D.,
RA Richardson P.;
RT "Complete sequence of chromosome of Pelobacter propionicus DSM 2379.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000482; ABK98304.1; -; Genomic_DNA.
DR RefSeq; WP_011734617.1; NC_008609.1.
DR AlphaFoldDB; A1ALT4; -.
DR SMR; A1ALT4; -.
DR STRING; 338966.Ppro_0673; -.
DR EnsemblBacteria; ABK98304; ABK98304; Ppro_0673.
DR KEGG; ppd:Ppro_0673; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_1_7; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000006732; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 3.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1499
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000300366"
SQ SEQUENCE 1499 AA; 167644 MW; 5D7BFDEFC13A23A8 CRC64;
MAYSIANNHL LRKTFTKIKN IIDIPNLIDI QKNSYRRFLQ QEGVSESRNN TGLEAVFRSV
FPIKDFSESA SLEYVSYSLS KPKYDVVECH QRGMTFAAPM KVKVRLVIWD TGKESGIRAI
KDIKEQEVYF GEIPLMTDNG TFIINGTERV IVSQLHRSPG VFYDHDKGKT HSSGKVLYSA
RVIPYRGSWL DFEFDHKDIL YVRIDRRRKM PATVLLKALG YSAEQLLNYY YKSEEIFLTG
ETPSKSIDAE LLTLQKALVD VVDPKSGEVI VKANRKFTKA SIRKMVEHDI KAVPITFDSI
IGRYASSDVI DPATGEVLLE CNEEVTAEKF DEIKAKGVES FRLLFIDNLH ITSSFRDTLL
MDKISTNDEA LIEIYRRLRP GDPPTLKSSL ALFENLFFNP ERYDLSAVGR LKLNFKLGLK
VWPECTVLNA PCMFGAEDIA SFDELFRLLL AADNRFSQYV LARLPEDFVK VLRKHEPSQP
VAEKLREQLL KELNNLVKDP DFYQKELFTG LALSQQTVAL TEAIEGGVFE ENRRVIEVLR
RNRMIFEDLY APVVLTSPKN DILEIVRYLI DLKNGRGAID DIDHLGNRRV RAVGELLENQ
YRIGLVRMER AIKERMSLQE VENLMPHDLI NSKPVSAVVK EFFGSSQLSQ FMDQTNPLSE
VTHKRRLSAL GPGGLTRERA GFEVRDVHPT HYGRVCPIET PEGPNIGLIA SLSTYARIND
HGFVETPYRI VLDGKLTNEV RFFSALEEEG HAIAQANAEV DAEGRFVNDY VSARKSGEFI
LVHRDEIELM DVAPKQLVSV AAALIPFLEN DDANRALMGS NMQRQAVPLL RADSPLVGTG
MERIVAKDSG VSVIARHNGV VESVDASRIV VKIDESEVDE TGTGVDIYNL IKFARSNQNT
CINNKPVVKV GDVVKRHDVI ADGPSTDMGE LALGQNIVVA FMPWGGYNFE DSILVSEKLV
KDDRYTSIHI EEYECVARDT KLGKEEITSD IPNLGEEALK DLDESGIIRI GAEVKPGDIL
VGKITPKGET QLSPEEKLLR AIFGEKAGDV RDTSLTVPPG VEGTVIGAKV FSRKGADKDT
RTELIEKAEE EKLRKDEQDE IRIIRQSAEG KLHRLLIGKS LSVKLEDGEG NLILAKGKEI
TAEALKSLSI NDMGAISVSD DGQTDDNVSK VIDTLNRQIE LIQSVFEDKI QKLRRGDDLP
PGVIKMVKVY IAIKRKLQVG DKMAGRHGNK GVVSRILPEE DMPYMEDGRP VEIVLNPLGV
PSRMNVGQIL ETHLGWAAKG IGWRIEEMLQ KQTSAESLKA YLKDVYGDDE VGTFIDGMDQ
EELMLVCRRL QRGVSMASPV FEGASEDKIK SMLGKAGFHS SGQVTLFDGR SGDPFKHKVT
VGVMYVLKLH HLVDDKIHAR SIGPYSLVTQ QPLGGKAQFG GQRLGEMEVW AMEAYGAAYA
LQEFLTVKSD DVSGRTRMYE AIVKGKHTLE PGLPESFNVL IKELQSLCLD VELLEGEDE
