RPOB_PSEA6
ID RPOB_PSEA6 Reviewed; 1342 AA.
AC Q15YB1;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 25-JUL-2006, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Patl_0598;
OS Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Pseudoalteromonas.
OX NCBI_TaxID=342610;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6c / ATCC BAA-1087;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Karls A.C.,
RA Bartlett D., Higgins B.P., Richardson P.;
RT "Complete sequence of Pseudoalteromonas atlantica T6c.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000388; ABG39127.1; -; Genomic_DNA.
DR RefSeq; WP_011573497.1; NC_008228.1.
DR AlphaFoldDB; Q15YB1; -.
DR SMR; Q15YB1; -.
DR STRING; 342610.Patl_0598; -.
DR PRIDE; Q15YB1; -.
DR EnsemblBacteria; ABG39127; ABG39127; Patl_0598.
DR KEGG; pat:Patl_0598; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_0_6; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000001981; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1342
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000300374"
SQ SEQUENCE 1342 AA; 149786 MW; 6EBEE42B4EECA4B9 CRC64;
MVYSYSEKKR IRKDFGKRPQ VLEIPYLLSI QLDSFKKFID LDVDGQHGLE AAFRSVFPIK
SYSGNAELQY VSYRLGEPVF DVKECQIRGV TFSAPLRVKL RLVLFDREAA PGTVKDIKEQ
EVYMGEIPLM TENGTFVING TERVIVSQLH RSPGVFFDHD KGKTHSSGKV LYNARVIPYR
GSWLDFEFDP KDNLYVRIDR RRKLPATIML RALEIPTEEI LGMFFEKNQV RIDGNRFMSD
IVPDRLRGET AQFDILDSDG NVLVEAGRRI SARHTRALEK AGIVELEVPA EYLVGRVFAC
DYVDQETGEL VVAANDLLTL ENVLALKEAG YTTFETLYIN ELDHGAYISD TLRIDSSTNR
LEALVEIYRM MRPGEPPTKD AAETLFTNLF FSEDRYDLSS VGRMKFNRRL GRETSIGAGT
LDKDDIVDVM KQLITIRDGK DDVDDIDHLG NRRIRSVGEM AENQFRVGLV RVERAVKERL
SLGDLDAVMP QDLINAKPIS AAVKEFFGSS QLSQFMDQNN PLSEVTDKRR ISALGPGGLT
RERAGFEVRD VHPTHYGRVC PIETPEGPNI GLINSLASFA RTNDFGFLET PYRKIVDGVV
TDEIDYLSAI EEGQFSIAQA NVVLDETGRL ADDLIPCRHR GETTLKESSE ITYMDVSPQQ
IVSIAASIIP FLEHDDANRA LMGANMQRQA VPTLIADKPL VGTGMEKTVA VDSGVTVVAK
RGGRVDYVDA SRIVIKVNEE ETVAGEAGID IYNLTKYTRS NQNTCINQRP TCNVGEPIVA
GDVLADGPST DLGELALGQN MRIAFMPWNG YNFEDSILIS ERVAMEDRFT TIHIQELSCV
ARDTKLGPEE ISSDIPNVGE SALGKLDESG VVYIGAEVKG GDILVGKVTP KGETQLTPEE
KLLRAIFGEK ASDVKDTSLR VPNSVRGTVI DVQVFTRDGV EKDKRALEIE GMQLRQVKKD
LSDEFNILAD GIFARAKNLL IKSGIEESRL ESAQREKWFD LTLTDEDAQT ELDQIAEQFV
EIKADFDKKF EIKRRKITQG DDLQPGVLKI VKVYLAVKRQ IQPGDKMAGR HGNKGVISTI
KPVEDMPYDV NGTPVDIVLN PLGVPSRMNI GQILETHLGM AAHGIGVKID RMLKEHEEMA
KLRSFLKEVY GAGTTHQEVD LDNFSDDEIT RLADNLRKGV PMATPVFDGA TEAEIKHMLT
LADLPESGQI ALFDGRTGRE FERPVTVGYM YMLKLNHLVD DKMHARSTGS YSLVTQQPLG
GKAQFGGQRF GEMEVWALEA YGAAYTLQEM LTVKSDDVNG RTKMYKNIVD GDHRMEPGMP
ESFNVLLKEI RSLGINIELE EQ
