RPOB_PSYIN
ID RPOB_PSYIN Reviewed; 1346 AA.
AC A1T065;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Ping_3446;
OS Psychromonas ingrahamii (strain 37).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC Psychromonadaceae; Psychromonas.
OX NCBI_TaxID=357804;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=37;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Staley J.,
RA Richardson P.;
RT "Complete sequence of Psychromonas ingrahamii 37.";
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000510; ABM05130.1; -; Genomic_DNA.
DR RefSeq; WP_011771682.1; NC_008709.1.
DR AlphaFoldDB; A1T065; -.
DR SMR; A1T065; -.
DR STRING; 357804.Ping_3446; -.
DR EnsemblBacteria; ABM05130; ABM05130; Ping_3446.
DR KEGG; pin:Ping_3446; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_3_6; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000000639; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 2.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 2.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1346
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000300379"
SQ SEQUENCE 1346 AA; 150448 MW; 054C8960F6476339 CRC64;
MGYSYTEKKR IRKDFGKRPQ VMEKPYLLSI QLDSFKRFIE VDLTGEVGLE AAFNSIFPIA
SYSGTSELQY VSYRLGEPVF DVKECQIRGV TYSASLRVKL RLVIYDRDAP AGTVKDIREQ
EVYMGEMPLM TENGTFVING TERVIVSQLH RSPGVFFDHD KGKTHSSGKV LYNARVIPYR
GSWLDFEFDP KDNLFVRIDR RRKLPATIML RALEYSTQEI LAIFYDTTKF DIKDGVISMS
LIADRLRGEM ALFDIAANGK IYVEQGKRIT ARHIKQLEKD NINTLDVPVE YIAEKDLVVA
KDYISKETGE IIVSANDILT LEILAELTQS GITSFDIIYT NELDCGSFIS DTLRVDSSSN
RLEALVEIYR MMRPGEPPTK DAAEGLFHNL FFAEERYELS KVGRMKFNRR VGIDGDEGAG
ILSKDDILSV MKTLIAIRNG DGIVDDIDHL GNRRIRCVGE MAENQFRVGL VRVERAVRER
LSLGDLDATM PQDLINAKPI SAAVKEFFGS SQLSQFMDQN NPLSEVTHKR RISALGPGGL
TRERAGFEVR DVHPTHYGRL CPIETPEGPN IGLINSLATF SRTNSYGFLE TPYRKVENGK
PTDQVEYLSA IEEGSFVIAQ ASASIDENGL LDEELIPCRH KGESTFLSPA DIDYMDVSPQ
QIISVAASLI PFLEHDDANR ALMGSNMQRQ AVPTLRADKP LVGTGIERRL AIDSGVTIIA
KRSGVIDYVD ASRIVVKVDD NELLPGEAGI DIYNLTKYTR SNQNTCINQK PTCEPGEPIV
RGDVLADGPS TDMGDLALGQ NMKIAFMPWN GYNFEDSILI SERVSQEDRF TTIHIQEFSC
VARETKLGSE EISADIPNVG EAALSKLDES GIVYVGAEVK PGDILVGKVT PKGETQLTPE
EKLLRAIFGE KASDVKDSSL RVAASTYATV IDVQVFTRDG VEKDKRALEI EEMQLKAAKK
DLTEKFKILE NAIYEKALAI LVGAGQDEAR LLQMPRAQWL EVQIDDETKQ SYLDQIITQY
DEVKADYDKE FDIKRRKITQ GDDLAPGVQK IVKVYLAVRR RLQPGDKMAG RHGNKGVISN
IVPVEDMPHD EFGVPVDIVL NPLGVPSRMN IGQVLETHLG LAAKGVGEKL ERMIKYQRDI
EITKVREFVQ KLYSFGDAPC HVDLNDFDDE AVMRLAKNLY KGLPVATPAF DGANEGEIRE
LLRMADLPES GQLQLTDGRT GIQFERPVTV GYMYMLKLNH LVDDKMHARS TGSYSLVTQQ
PLGGKAQFGG QRFGEMEVWA LEAYGAAYTL QEMLTVKSDD VNGRTKMYKN IVDGDHRMEP
GMPESFNVLL KEIRSLSINI ELDESN
