RPOB_PSYWF
ID RPOB_PSYWF Reviewed; 1372 AA.
AC A5WH35;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321};
GN OrderedLocusNames=PsycPRwf_2036;
OS Psychrobacter sp. (strain PRwf-1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Psychrobacter.
OX NCBI_TaxID=349106;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PRwf-1;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome of Psychrobacter sp. PRwf-1.";
RL Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000713; ABQ94976.1; -; Genomic_DNA.
DR RefSeq; WP_011961250.1; NC_009524.1.
DR AlphaFoldDB; A5WH35; -.
DR SMR; A5WH35; -.
DR STRING; 349106.PsycPRwf_2036; -.
DR PRIDE; A5WH35; -.
DR EnsemblBacteria; ABQ94976; ABQ94976; PsycPRwf_2036.
DR KEGG; prw:PsycPRwf_2036; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_3_6; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW Transferase.
FT CHAIN 1..1372
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_1000073240"
SQ SEQUENCE 1372 AA; 152908 MW; 67E588B39A9BEE86 CRC64;
MAYSYTEKKR IRKSFAELPH VMDIPYLLAI QVDSYEQFLQ ENKKPKAREN TGLQAAFSSI
FPIESNSNNA ELQFVEYYLG APEFDERECI SRGSTFAAPL RVKIRLVIKD KDSKDKNSKA
AIKDIREQNV YMGEIPLMTD NGTFIINGTE RVIVSQLHRS PGVFFDHDKG KSHSSGKVLY
NARIIPYRGS WLDFEFDAKD LVFARIDRRR KLLGTIILRA LGMDTNEILD TFFEKVSVYK
GEEQFEIDLV ADRLRGEMAQ FDIVSPDGEV LVEQGKRINA RRIRQIEQSG MKKLAVPDEY
LYERILAEDI VVNDEVIAKA NTLIDHELLV KLSAFEASES IKEFKILFTN DIDHGTYIAD
TLRADSTGSR EEALIEIYKV MRPGEPPTID TAEKLFESMF FNADRYDLSN VGRMKFNRRL
GRTFENTDDP DIKREQSVLT KDDIIDVLKE LINIRNGIGE VDDIDHLGNR RIRSVGEMAE
NQFRVGLVRV ERAVKERLSS AESDNLSPQD LINSKPVAAA VKEFFGSSQL SQFMDQNNPL
SEITHKRRIS ALGPGGLTRE RAGFEVRDVH NTHYGRVCPI ETPEGPNIGL INSLATFAKT
NEFGFLETPY RKVVDGKVTD DIEYLSAIEE VGTVIAQADS ELDENGVLAE EMVMVRSGGE
SVRMPSDKVT HMDVSPSQVV SVAASLIPFL EHDDANRALM GSNMQRQAVP TLRADKPLVG
TGMERHVARD SGVCVIARRG GVIEDVDASR IVVRVNEDEM QAGEAGIDIY NLIKYTRSNQ
NTCINQRIIV NQGDEIAGGD ILADGPSTDL GELALGQNMR VAFMPWNGYN FEDSILLSER
VVKEDRFTTI HIQELTCVAR DTKLGTEEIT ADIPNVGEAA LSALDESGIV YIGAEVDAGD
ILVGKVTPKG ETQLTPEEKL LRAIFGEKAA DVKDTSLRVP TSTKGTVIDV QVFTRDGVEK
DARAKSIEKS QLDNYRKDLK EELRIFEEAA RSRISHLLDG QAISGGAGLK SGTVLAESEL
LEMSLETLLD IQPVEEEIAE RLTQIQEFLV DKQKDIDTKF AEKKRKLTAG DDLAHGVQKI
VKVYLAVKRR IQPGDKMAGR HGNKGVVSRI MPVEDMPYDE NGNPVDIVLN PLGVPSRMNI
GQVLETHLGM AAKGLGDKIN GMIKAQAAVT ELREFLDKIY NKVGGEQVDL DSLSDDDIRA
LAQNLRDGVP MGTAVFDGAR EVQIDELLEL AGYPSSGQQT LYDGRTGQKF DRPVTVGYMY
MLKLNHLVDD KMHARSTGSY SLVTQQPLGG KAQFGGQRFG EMEVWALEAY GATYTLQEML
TVKSDDVEGR TRMYKNIVDG EQYMDPGMPE SFNVLTKEIK SLGINIELKE SN
