RPOB_RHOP2
ID RPOB_RHOP2 Reviewed; 1390 AA.
AC Q2IXS0;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 07-MAR-2006, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=RPB_2285;
OS Rhodopseudomonas palustris (strain HaA2).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Bradyrhizobiaceae; Rhodopseudomonas.
OX NCBI_TaxID=316058;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HaA2;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Pelletier D.A.,
RA Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P.;
RT "Complete sequence of Rhodopseudomonas palustris HaA2.";
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000250; ABD06990.1; -; Genomic_DNA.
DR RefSeq; WP_011441177.1; NC_007778.1.
DR AlphaFoldDB; Q2IXS0; -.
DR SMR; Q2IXS0; -.
DR STRING; 316058.RPB_2285; -.
DR PRIDE; Q2IXS0; -.
DR EnsemblBacteria; ABD06990; ABD06990; RPB_2285.
DR KEGG; rpb:RPB_2285; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_3_5; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000008809; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW Transferase.
FT CHAIN 1..1390
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000300390"
SQ SEQUENCE 1390 AA; 155046 MW; D55ED38BDB01B4C8 CRC64;
MAQQTFTGRK RVRKFFGHIR EVAEMPNLIE VQKASYDQFL MVAEPPGGRD DEGLQAVFRS
VFPISDFSNA SMLEFVRYEF EPPKYDVDEC RQRGMTYAAP LKVTLRLIVF DIDEETGARS
VKDIKEQDVY MGDIPLMTMN GTFVVNGTER VIVSQMHRSP GVFFDHDKGK THSSGKLLFA
ARVIPYRGSW LDIEFDAKDI VFARIDRRRK IPVTSLMFAL GLDGEEILST FYNKILYKRT
KEGWRVPFDA SRFRGYSTVN DLIDADTGKV VLEAGKKLTV RAARQLQEKG LKALRLSDSE
LVGNYLAEDL VNPKTGEIFA EAGDELTGKP IKGDDKEIEL FVGATPMKAI LEQGYKELPL
LDIDHVNVGP YIRNTLSADK NMTREDALFD IYRVMRPGEP PTLDSAQNMF QSLFFDAERY
DLSAVGRVKM NMRLDLDAPD THRTLRKEDI LAVIKTLVGL RDGKGEIDDI DHLGNRRVRS
VGELMENQYR IGLLRMERAI KERMSSVDID TVMPQDLINA KPAAAAVREF FGSSQLSQFM
DQTNPLSEIT HKRRLSALGP GGLTRERAGF EVRDVHPTHY GRICPIETPE GPNIGLINSL
ATFARVNKYG FVETPYRKVK EGRVTDEVVY LSAMEEGRYA VAQANISLDA KGRFTDDLIV
CRAGGTRDVV LIPADQVDYM DVSPKQLVSV AAALIPFLEN DDANRALMGS NMQRQAVPLV
RAEAPFVGTG MEGVVARDSG AAIAARRTGV IDQIDATRIV IRATEDLDPT KSGVDIYRLM
KYQRSNQSTC INQRPLVKVG DKVAKGDIIA DGPSTDLGEL ALGRNVLVAF MPWNGYNFED
SILLSERIVK EDVFTSIHIE EFEVMARDTK LGPEEITRDI PNVSEEALKN LDEAGIVYIG
AEVRAGDILV GKITPKGESP MTPEEKLLRA IFGEKASDVR DTSLRVPPGV QGTIVEVRVF
NRHGVDKDER ALAIEREEIE RLAKDRDDEQ AILDRNVYGR LADLLDNRQG VAGPKGFKKD
TKITRAVLEE YPKSQWWLFA SPNDKLMAEI EAMRKQYDES KKGLEQRFLD KVEKLQRGDE
LPPGVMKMVK VFVAVKRKIQ PGDKMAGRHG NKGVVSKIVP IEDMPFLEDG THADIVLNPL
GVPSRMNVGQ ILETHLGWAC AGMGKKIGQT IDAYYQRQDL KPLRETLKKI YGDDETIKSL
DDGELIELGR NLSHGVPIAT PVFDGAKEAD IEEMLKLAGF DASGQSTVYD GRTGDEFDRK
VTVGYIYMLK LHHLVDDKIH ARSIGPYSLV TQQPLGGKAQ FGGQRFGEME VWALEAYGAA
YTLQEMLTVK SDDVAGRTKV YEAIVRGDDT FEAGIPESFN VLVKEMRSLG LNVDLHNSKL
GVPPPAEAAE
