ID   RPOB_RHOPA              Reviewed;        1374 AA.
AC   Q6N4R9;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=RPA3268;
OS   Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=258594;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-98 / CGA009;
RX   PubMed=14704707; DOI=10.1038/nbt923;
RA   Larimer F.W., Chain P., Hauser L., Lamerdin J.E., Malfatti S., Do L.,
RA   Land M.L., Pelletier D.A., Beatty J.T., Lang A.S., Tabita F.R.,
RA   Gibson J.L., Hanson T.E., Bobst C., Torres y Torres J.L., Peres C.,
RA   Harrison F.H., Gibson J., Harwood C.S.;
RT   "Complete genome sequence of the metabolically versatile photosynthetic
RT   bacterium Rhodopseudomonas palustris.";
RL   Nat. Biotechnol. 22:55-61(2004).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR   EMBL; BX572603; CAE28709.1; -; Genomic_DNA.
DR   RefSeq; WP_011158811.1; NC_005296.1.
DR   AlphaFoldDB; Q6N4R9; -.
DR   SMR; Q6N4R9; -.
DR   STRING; 258594.RPA3268; -.
DR   PRIDE; Q6N4R9; -.
DR   EnsemblBacteria; CAE28709; CAE28709; RPA3268.
DR   GeneID; 66894354; -.
DR   KEGG; rpa:RPA3268; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_0_5; -.
DR   OMA; FMTWEGY; -.
DR   PhylomeDB; Q6N4R9; -.
DR   BioCyc; RPAL258594:TX73_RS16670-MON; -.
DR   Proteomes; UP000001426; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 1.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..1374
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000224101"
SQ   SEQUENCE   1374 AA;  153599 MW;  1110C67B5CA5CF48 CRC64;
     MAQQTFTGRK RVRKFFGHIR EVAEMPNLIE VQKASYDQFL MVAEPPGGRP DEGLQAVFRS
     VFPISDFSNA SMLEFVRYEF EPPKYDVDEC RQRGMTYAAP LKVTLRLIVF DIDEETGARS
     VKDIKEQDVY MGDIPLMTMN GTFIVNGTER VIVSQMHRSP GVFFDHDKGK THSSGKLLFA
     ARIIPYRGSW LDIEFDAKDI VYARIDRRRK LPVTSLMFAL GLDGEEILST FYNKILYKRT
     KEGWRVPFDV NRFRGYSTVN DLIDADTGKV VLEAGKKLTV RAARQLQEKG LKALRMSDEE
     LVGNYLAEDL VNPKTGEIYA EAGEEITDKT LKMLNEQGYK ELPLLDIDHV NVGPYIRNTL
     NADKNMTRED ALFDIYRVMR PGEPPTLDSA QNMFQSLFFD AERYDLSAVG RVKMNMRLDL
     DAPDTHRTLR KEDILAVIKT LVGLRDGKGE IDDIDHLGNR RVRSVGELME NQYRIGLLRM
     ERAIKERMSS VDIDTVMPQD LINAKPAAAA VREFFGSSQL SQFMDQTNPL SEITHKRRLS
     ALGPGGLTRE RAGFEVRDVH PTHYGRICPI ETPEGPNIGL INSLATFARV NKYGFVETPY
     RKVKEGRVTD EVVYLSAMEE GRYAVAQANV SLDAKGKFTD DLVVCRAGGT RDVVPMPADQ
     VDYMDVSPKQ LVSVAAALIP FLENDDANRA LMGSNMQRQA VPLVRAEAPF VGTGMEGVVA
     RDSGAAIAAR RTGIIDQIDA TRIVIRATED LDPTKSGVDI YRLMKYQRSN QSTCINQRPL
     VKVGDHVKKG DIIADGPSTD LGELALGRNV LVAFMPWNGY NFEDSILLSE RIVKEDVFTS
     IHIEEFEVMA RDTKLGPEEI TRDIPNVSEE ALKNLDEAGI VYIGAEVRAG DILVGKITPK
     GESPMTPEEK LLRAIFGEKA SDVRDTSLRV PPGVQGTIVE VRVFNRHGVD KDERALAIER
     EEIERLAKDR DDEQAILDRN VYGRLADLLD GRQGIAGPKG FKKDTKITRA VLEEYPKSQW
     WLFAAPNDKL MAEIEAMRKQ YDESKKGLEQ RFLDKVEKLQ RGDELPPGVM KMVKVFVAVK
     RKIQPGDKMA GRHGNKGVVS KIVPIEDMPF LEDGTHADIV LNPLGVPSRM NVGQILETHL
     GWACAGLGKR IGETIDAYYQ SQDLKPLRET LRKIYGEDET IKSLDDGELL ELGRNLSHGV
     PIATPVFDGA KEADIEEMLK LAGFDASGQS TVYDGRTGDQ FDRRVTVGYI YMLKLHHLVD
     DKIHARSIGP YSLVTQQPLG GKAQFGGQRF GEMEVWALEA YGAAYTLQEM LTVKSDDVAG
     RTKVYEAIVR GDDTFEAGIP ESFNVLVKEM RSLGLNVDLH NSKLAAPPPA EAAE