RPOB_RHOPB
ID RPOB_RHOPB Reviewed; 1373 AA.
AC Q211D8;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 18-APR-2006, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=RPC_3458;
OS Rhodopseudomonas palustris (strain BisB18).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Bradyrhizobiaceae; Rhodopseudomonas.
OX NCBI_TaxID=316056;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BisB18;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Pelletier D.A., Kyrpides N., Anderson I., Oda Y., Harwood C.S.,
RA Richardson P.;
RT "Complete sequence of Rhodopseudomonas palustris BisB18.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000301; ABD88998.1; -; Genomic_DNA.
DR RefSeq; WP_011473885.1; NC_007925.1.
DR AlphaFoldDB; Q211D8; -.
DR SMR; Q211D8; -.
DR STRING; 316056.RPC_3458; -.
DR EnsemblBacteria; ABD88998; ABD88998; RPC_3458.
DR KEGG; rpc:RPC_3458; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_0_5; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 2.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 2.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW Transferase.
FT CHAIN 1..1373
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000300388"
SQ SEQUENCE 1373 AA; 153687 MW; 5B56D2B1169AF3FB CRC64;
MAQQTFTGRK RVRKFFGHIR EVAEMPNLIE VQKASYDQFL MVDEPVGGRL DEGLQAVFRS
VFPISDFSNT SMLEFVRYEF EPPKYDVDEC RQRGMTYAAP LKVTLRLIVF DIDEETGARS
VKDIKEQDVY MGDIPLMTMN GTFVVNGTER VIVSQMHRSP GVFFDHDKGK THSSGKLLFA
ARVIPYRGSW LDIEFDAKDI VFARIDRRRK IPVTSLMFAL GLDGEEILST FYKKIQYKKI
KEGWRVPFDS NRFRGYSTIN DLIDADTGKV VLEAGKKLTV RAARQLQEKG LKALRLSDEE
LVGNYLAEDL VNPKTGEIYA EAGEEITEKS LKGLNEQGYK ELPLLDIDHV NIGAYIRNTL
AADKNMTRED ALFDIYRVMR PGEPPTIDSA QNMFQSLFFD SERYDLSAVG RVKMNMRLEL
DAPDTHRTLR KEDILAVIKT LVGLRDGRGE IDDIDHLGNR RVRSVGELME NQYRIGLLRM
ERAIKERMSS VDIDTVMPQD LINAKPAAAA VREFFGSSQL SQFMDQTNPL SEITHKRRLS
ALGPGGLTRE RAGFEVRDVH PTHYGRICPI ETPEGPNIGL INSLATFARV NKYGFVETPY
RRCKDGRVTD EVVYLSAMEE GRYSVAQANV QLDPKGRFVE DLIVCRDGGT RDVVLIPADK
VDFMDVSPKQ LVSVAAALIP FLENDDANRA LMGSNMQRQA VPLVRAEAPF VGTGMEGVVA
RDSGAAIAAR RTGVIDQIDA TRIVIRATDD LDPTKSGVDI YRLMKYQRSN QSTCINQRPL
VKVGDMVAKG DIIADGPSTD LGELALGRNV LVAFMPWNGY NFEDSILLSE RIVKDDVFTS
IHIEEFEVMA RDTKLGPEEI TRDIPNVSEE ALKNLDEAGI VYIGAEVRAG DILVGKITPK
GESPMTPEEK LLRAIFGEKA SDVRDTSLRV PPGVQGTIVE VRVFNRHGVD KDERALAIER
EEIERLAKDR DDEQAILDRN VYGRLADLLE NRQGIAGPKG FKKDTKITRA VIEEYPKSQW
WLFASPNDKL MAEIEAMRKQ YDESKKGLEQ RFLDKVEKLQ RGDELPPGVM KMVKVFVAVK
RKIQPGDKMA GRHGNKGVVS KIVPIEDMPF LEDGTHADIV LNPLGVPSRM NVGQILETHL
GWACAGLGKR IGQTIDAYYQ KQDLKPMRET LRKIYGEDET IKSLNDAELL ELARNLKPGV
PIATPVFDGA KEADIEEMLK LAGLDASGQS TVYDGRTGDT FDRKVTVGYI YMLKLHHLVD
DKIHARSIGP YSLVTQQPLG GKAQFGGQRF GEMEVWALEA YGAAYTLQEM LTVKSDDVAG
RTKVYEAIVR GDDTFEAGIP ESFNVLVKEM RSLGLNVDLH NSKLATPTSE AAE
