ID   RPOB_RHORT              Reviewed;        1393 AA.
AC   Q2RQV3;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Rru_A2695;
OS   Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 /
OS   NCIMB 8255 / S1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Rhodospirillum.
OX   NCBI_TaxID=269796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1;
RX   PubMed=21886856; DOI=10.4056/sigs.1804360;
RA   Munk A.C., Copeland A., Lucas S., Lapidus A., Del Rio T.G., Barry K.,
RA   Detter J.C., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D.,
RA   Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Kyrpides N.C.,
RA   Mavromatis K., Richardson P., Rohde M., Goeker M., Klenk H.P., Zhang Y.,
RA   Roberts G.P., Reslewic S., Schwartz D.C.;
RT   "Complete genome sequence of Rhodospirillum rubrum type strain (S1).";
RL   Stand. Genomic Sci. 4:293-302(2011).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR   EMBL; CP000230; ABC23492.1; -; Genomic_DNA.
DR   RefSeq; WP_011390505.1; NC_007643.1.
DR   RefSeq; YP_427779.1; NC_007643.1.
DR   AlphaFoldDB; Q2RQV3; -.
DR   SMR; Q2RQV3; -.
DR   STRING; 269796.Rru_A2695; -.
DR   PRIDE; Q2RQV3; -.
DR   EnsemblBacteria; ABC23492; ABC23492; Rru_A2695.
DR   KEGG; rru:Rru_A2695; -.
DR   PATRIC; fig|269796.9.peg.2803; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_0_5; -.
DR   OMA; FMTWEGY; -.
DR   OrthoDB; 9601at2; -.
DR   PhylomeDB; Q2RQV3; -.
DR   Proteomes; UP000001929; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 1.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 1.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..1393
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000237311"
SQ   SEQUENCE   1393 AA;  154912 MW;  8392E16F36BB7AFD CRC64;
     MTKSLTSRKR IRKDFGRIPT VAPMPNLIEV QKSSYDQFLQ IGVPVDKRTD SGLQEVFKSV
     FPIRDFSGKG ELEFVAYELE EPKYDTDECQ QRGMTFAAPL KVTLRLLVWD VDEETGARSI
     RDIKEQDVYM GDMPLMTSNG TFIINGTERV IVSQMHRSPG VFFDHDKGKT HSSGKFLFAA
     RVIPYRGSWL DFEFDAKDMV YVRIDRRRKL PVTTLLYALE GAAATALREA RTAEGRSVDP
     SEIAGMTSEE ILDFFYQKLS YKRDDKGWKV DFKPDHLRGV KLMFDLVDAA TGEVKIEAGT
     KVTPRAARKL AEDGMTEMRV FTEELVGRYA AEDMINEASG EIYAEAGEEL TEAMLADMEK
     AGFTELRVLH IDHVNVGPYV RNTLAMDKNT TREEALIDIY RVMRPGEPPT LETADALFKG
     LFFDSERYDL SAVGRVKMNA RLGFTMQEAP DTMRVLRKED VLHIIRQLVE LKDGKGEIDD
     IDHLGNRRVR SVGELMENQY RVGLLRMERA IRERMSSVDI DTVMPHDLIN AKPAAAAVRE
     FFGSSQLSQF MDQTNPLSEI THKRRLSALG PGGLTRERAG FEVRDVHPTH YGRICPIETP
     EGPNIGLINS LATFARVNQY GFIESPYRKV VEGTVTDEVT YMSAMEEGKY VIAQANAALT
     EDGHFADDLI SCRKASDFEM VQPQDIDYID VSPKQLVSVA AALIPFLEND DANRALMGSN
     MQRQAVPLVK AEAPYVGTGM EAAVARDSGA TIAAKRAGVV QQVDATRIVI RATEDLKIAE
     SGVDIYRLQK FQRSNQSTCI NQRPLVKVGD LVGRGEILAD GPLTEMGELA LGRNVLVAFM
     PWNGYNFEDS ILISERIVSD DVFTSIHIEE FEVMARDTKL GQEEITRDIP NVGEEALKNL
     DEAGIVYIGA EVQAGDILVG KVTPKGESPM TPEEKLLRAI FGEKASDVRD TSLRIPPGVT
     GTVVEVRVFN RRGVEKDERA LAIERQEIES LAKDRDDERA ILEGSFARRL KELLIGQKVV
     GGPRGMATGG VISEDLLSGY TAAQWRQIAV ENDETATEIE GLKKAYEESI AKIQERFENK
     VEKLQRGDEL PPGVLKMVKV FVAVKRKLQP GDKMAGRHGN KGVISKINPI EDMPYLEDGT
     YVDIVLNPLG VPSRMNVGQI LETHLGWACR GLGAQIGALL EQVKRGLIPI NDLREKLDDV
     YGPRHAKEDL APMGDDQIKE LAFNLRSGVP IATPVFDGAR ESDIVDMLRK AGLDSSGQVT
     LSDGRTGEPF DRKVTVGYIY MLKLHHLVDD KIHARSIGPY SLVTQQPLGG KAQFGGQRFG
     EMEVWALEAY GAAYTLQEML TVKSDDVSGR TKVYEAIVKG DDTFEAGIPE SFNVLVKEMR
     SLGLDVELGQ SSF