RPOB_ROSS1
ID RPOB_ROSS1 Reviewed; 1229 AA.
AC A5USR7;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=RoseRS_1265;
OS Roseiflexus sp. (strain RS-1).
OC Bacteria; Chloroflexi; Chloroflexia; Chloroflexales; Roseiflexineae;
OC Roseiflexaceae; Roseiflexus.
OX NCBI_TaxID=357808;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS-1;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.;
RT "Complete sequence of Roseiflexus sp. RS-1.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000686; ABQ89670.1; -; Genomic_DNA.
DR RefSeq; WP_011956022.1; NC_009523.1.
DR AlphaFoldDB; A5USR7; -.
DR SMR; A5USR7; -.
DR STRING; 357808.RoseRS_1265; -.
DR PRIDE; A5USR7; -.
DR EnsemblBacteria; ABQ89670; ABQ89670; RoseRS_1265.
DR KEGG; rrs:RoseRS_1265; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_1_0; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000006554; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 2.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1229
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000329186"
SQ SEQUENCE 1229 AA; 137727 MW; 1C310B352F614BB3 CRC64;
MPPLTQSVVL QPLIVPNDVG IDALHRGKIE RYSFARISNA IELPKLIETQ LNSFEWFRKE
GLRELFEEIS PITDFTGKNM ELRFLDYHFG EPRYNEHECR ERGITYSAPI RVNVQLRILS
TGELKESEIF LGDFPLMTEN GTFVINGAER VVVSQLIRSP GVYFKEEKDP TSGRSLHSAK
LIPSRGAWLE FETNKRDVIS VKVDRKRKIP VTILLRAVLG WRANPDGSGQ WAPDNELDQR
GRDEEILELF AHLETGDHQY IKATLDKDPA RHAKEALLEL YKRLRPGDPP TLDNARNLIE
ALLFNPRRYD LSRVGRYKLN KNLWEKDTRP EVRRQAPDVK VRVLLPDDIF KIVERMIQLN
NGTPGLRADD IDHLGNRRVR TVGELIQQQF RVGLLRMERV IKERMSLQDP ETATPNALVN
IRPVVAAMRE FFGGAQLSQF MDQTNPLAEL THKRRLSALG PGGLSRDRAG FEVRDVHHSH
YGRICPVETP EGPNIGLIGT MSTYARVNEM GFLETPYRKV YREVPNASEW ERQGLLLRDV
RDLRTGELIA VRGTRVDAAV ARRIAVALLR GQILREDVVD PTTGEVIAHA GQEVNRALAE
RIVETPLKII KIRPVVSQEV DYLSADEEDR FVIVQANAPL DEHNRFLEGT VSVRYAGDFD
DVPIERVDYM DVSPKQVVSV STALIPFLEH DDANRALMGS NMQRQAVPLL RPDAPIVGTG
MEYVAARDSG QVVVAKADGV VLSATADEIV ILEDDGNERS YRLRKFMRSN QDTCINQRPI
VSRGQRVRKG DIIADSSSTD NGELALGQNV LVAFMPWEGG NFEDAILVSE RLVREDIFTS
IHIEKYEVEA RDTKLGPEEI TRDIPNVGQD SLRNLDDRGI IYIGAEVQPN DILVGKITPK
GETDLTAEER LLRAIFGEKA REVKDSSLRV PNGVRGKVID VKVFTRDDDV ELPVGVNQRV
DVLLCQKRKI SAGDKMAGRH GNKGVVSRIL PIEDMPFLPD GTPVDIILNP IGVPSRMNIG
QILETHLGWA AARLGYRVAT PVFDGATETE IKEWLKRADL PPDGKITLYD GRTGEAFDRP
VTVGYIYMMK LAHLVEDKIH ARSTGPYSLV TQQPLGGKAQ FGGQRFGEME VWALEAYGAA
YTLQEMLTVK SDDVVGRVKT YEAIVKGEPI QEAGVPESFK VLIKELQSLG LSVEVLSADE
TPVELTDDAD SDLAALDGIN LSGMERGEF
