ID   RPOB_SULDN              Reviewed;        1381 AA.
AC   Q30TP7;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Suden_0353;
OS   Sulfurimonas denitrificans (strain ATCC 33889 / DSM 1251) (Thiomicrospira
OS   denitrificans (strain ATCC 33889 / DSM 1251)).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Thiovulaceae; Sulfurimonas.
OX   NCBI_TaxID=326298;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33889 / DSM 1251;
RX   PubMed=18065616; DOI=10.1128/aem.01844-07;
RA   Sievert S.M., Scott K.M., Klotz M.G., Chain P.S.G., Hauser L.J., Hemp J.,
RA   Huegler M., Land M., Lapidus A., Larimer F.W., Lucas S., Malfatti S.A.,
RA   Meyer F., Paulsen I.T., Ren Q., Simon J., Bailey K., Diaz E.,
RA   Fitzpatrick K.A., Glover B., Gwatney N., Korajkic A., Long A.,
RA   Mobberley J.M., Pantry S.N., Pazder G., Peterson S., Quintanilla J.D.,
RA   Sprinkle R., Stephens J., Thomas P., Vaughn R., Weber M.J., Wooten L.L.;
RT   "Genome of the epsilonproteobacterial chemolithoautotroph Sulfurimonas
RT   denitrificans.";
RL   Appl. Environ. Microbiol. 74:1145-1156(2008).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR   EMBL; CP000153; ABB43634.1; -; Genomic_DNA.
DR   RefSeq; WP_011371988.1; NC_007575.1.
DR   AlphaFoldDB; Q30TP7; -.
DR   SMR; Q30TP7; -.
DR   STRING; 326298.Suden_0353; -.
DR   PRIDE; Q30TP7; -.
DR   EnsemblBacteria; ABB43634; ABB43634; Suden_0353.
DR   KEGG; tdn:Suden_0353; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_0_7; -.
DR   OMA; FMTWEGY; -.
DR   OrthoDB; 9601at2; -.
DR   Proteomes; UP000002714; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 1.
DR   Gene3D; 2.40.50.150; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..1381
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000237323"
SQ   SEQUENCE   1381 AA;  156405 MW;  3EC61E23327FB80C CRC64;
     MLNTLYSGNR LRVDFSKTPQ QIEVPNLLQL QQSSYNKFLM LEEKDRSQSG VETVFQSVFP
     IHDTQNRLTV EYIDSEVGKP KYTVRECMER GLTYAVSLRM KTRLILWDRD ENTKEKLGVK
     DIKEQSIFVR DIPLMTERTS FIINGVERVV VNQLHRSPGV IFKEEESTTS GNKLIYTGQI
     IPDRGSWLYF EYDPKDILYM RINKRRKVPV TIMFRALGYS KQDILKLFYP IQHINIVDNK
     FLMSFNPNDY SSRLTYDLVD KNGKILLASG KRLSAKKAQN FIDEGLSEVE YPLEVLLDRY
     LAKPIVDPET GEILFDAMTR IDETKLKKLS EIGVKNFSIA NDLAEGVDGS IINAFNADAD
     SLKLLKQTED IEDENHLSAI RIYKVMRPGE PVTKEAAKVF VNQLFFDPER YDLTKVGRMK
     MNHKLGLNIP EYITVLTHED IIESVKYVIK VKNGQGHIDD RDHLGNRRIR SIGELLGNEL
     HNGLIKMQKA IRDKLSTMSG PMNELMPHDL INSKMITSTI MEFFSGGQLS QFMDQTNPLS
     EVTHKRRLSA LGEGGLVKER AGFEVRDVHP THYGRICPIE TPEGQNIGLI NTLATYSKVN
     EHGFIEAPYK VMKEGKVTDE IVYLTATQEE GKKIAAASNK LDKDGQFIDK MVVTRVDGEI
     LHRPVTECNY ADLSSHMVVG VAASLIPFLE HDDANRALMG ANMQRQAVPL IKHEAPIVGT
     GVEKLVARDS WECVKARRSG IVEKVDGKHI YVMGDDDGEI YIDYYPLQKN LRTNQNTAFG
     QKPIVNIGQR VEIGQVIADG PNMDQGELAL GVNAMVAFMP WNGYNFEDAI VISERLIRKD
     AFTSVHIYEK EVEARELKHG VEEITRDIPN VRDDELSHLD ESGIIKIGTN VTGGMILVGK
     VSPKGEVKPT PEERLLRAIF GEKAGHVINK SLYCPPSMEG VVVDVKIFTK KGYDKDARTL
     ELEKEERDYL EREHYDRLLM IDKEEMLRVT KLLTKEPLIN DIKIGNTSYK AGDIINGEDL
     VEVNRFAMNA IIKSFSEEIQ SEYNKTKNYF QKEKRLFRDE HEEKLNILEK DDILPNGVVK
     HVKIYIATKR QLKVGDKMAG RHGNKGIVST IVPEVDMPYM EDGRGVDVCL NPLGVPSRMN
     IGQILEMHLG MAGRELGHQI TKEFESKQKD FIKNLRAKMI EIADVAQMMN AAKTLGDMSD
     ELLLHHARDW SRGVKFASPI FEGVNAVEFE KLFALAKMDT DGKTVLYNGL TGEKIKERVN
     VGYMYILKLH HLVDEKIHAR STGPYSLVTQ QPVGGKALFG GQRFGEMEVW ALEAYGASAV
     LKEMLTIKSD DVDGRVRAYK AITKGELVPE SGIPETLFVL TKELQSLALD VEIFDEVEDN
     E