RPOB_THET8
ID RPOB_THET8 Reviewed; 1119 AA.
AC Q8RQE9; Q5SHB7;
DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=TTHA1813;
OS Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8).
OC Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=300852;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=12198314; DOI=10.1107/s0907444902011770;
RA Vassylyeva M.N., Lee J., Sekine S.I., Laptenko O., Kuramitsu S.,
RA Shibata T., Inoue Y., Borukhov S., Vassylyev D.G., Yokoyama S.;
RT "Purification, crystallization and initial crystallographic analysis of RNA
RT polymerase holoenzyme from Thermus thermophilus.";
RL Acta Crystallogr. D 58:1497-1500(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27634 / DSM 579 / HB8;
RA Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T.,
RA Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.;
RT "Complete genome sequence of Thermus thermophilus HB8.";
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; AB083789; BAB89400.1; -; Genomic_DNA.
DR EMBL; AP008226; BAD71636.1; -; Genomic_DNA.
DR RefSeq; WP_011228935.1; NC_006461.1.
DR RefSeq; YP_145079.1; NC_006461.1.
DR PDB; 1IW7; X-ray; 2.60 A; C/M=1-1119.
DR PDB; 1SMY; X-ray; 2.70 A; C/M=1-1119.
DR PDB; 1ZYR; X-ray; 3.00 A; C/M=1-1119.
DR PDB; 2A68; X-ray; 2.50 A; C/M=1-1119.
DR PDB; 2A69; X-ray; 2.50 A; C/M=1-1119.
DR PDB; 2A6E; X-ray; 2.80 A; C/M=1-1119.
DR PDB; 2A6H; X-ray; 2.40 A; C/M=1-1119.
DR PDB; 2BE5; X-ray; 2.40 A; C/M=1-1119.
DR PDB; 2CW0; X-ray; 3.30 A; C/M=1-1119.
DR PDB; 2O5I; X-ray; 2.50 A; C/M=1-1119.
DR PDB; 2O5J; X-ray; 3.00 A; C/M=1-1119.
DR PDB; 2PPB; X-ray; 3.00 A; C/M=1-1119.
DR PDB; 3AOH; X-ray; 4.10 A; C/H/M=1-1119.
DR PDB; 3AOI; X-ray; 4.30 A; C/H/M=1-1119.
DR PDB; 3DXJ; X-ray; 3.00 A; C/M=1-1119.
DR PDB; 3EQL; X-ray; 2.70 A; C/M=1-1119.
DR PDB; 3WOD; X-ray; 3.60 A; C=1-1119.
DR PDB; 3WOE; X-ray; 2.35 A; A/C=703-830.
DR PDB; 3WOF; X-ray; 3.30 A; A/C/E/G/I/K/M/O/Q/S/U/W=703-830.
DR PDB; 4G7H; X-ray; 2.90 A; C/M=1-1119.
DR PDB; 4G7O; X-ray; 2.99 A; C/M=1-1119.
DR PDB; 4G7Z; X-ray; 3.82 A; C/M=1-1119.
DR PDB; 4GZY; X-ray; 3.51 A; C=1-1119.
DR PDB; 4GZZ; X-ray; 4.29 A; C=1-1119.
DR PDB; 4MQ9; X-ray; 3.35 A; C=1-1119.
DR PDB; 4OIN; X-ray; 2.80 A; C=1-1119.
DR PDB; 4OIO; X-ray; 3.10 A; C=1-1119.
DR PDB; 4OIP; X-ray; 3.40 A; C=1-1119.
DR PDB; 4OIQ; X-ray; 3.62 A; C=1-1119.
DR PDB; 4OIR; X-ray; 3.10 A; C=1-1119.
DR PDB; 4Q4Z; X-ray; 2.90 A; C=1-1119.
DR PDB; 4Q5S; X-ray; 3.00 A; C=1-1119.
DR PDB; 4WQS; X-ray; 4.31 A; C/M=1-1119.
DR PDB; 4WQT; X-ray; 4.40 A; C/H/M=1-1119.
DR PDB; 5D4C; X-ray; 3.28 A; C/M=1-1119.
DR PDB; 5D4D; X-ray; 3.00 A; C/M=1-1119.
DR PDB; 5D4E; X-ray; 3.08 A; C/M=1-1119.
DR PDB; 5E17; X-ray; 3.20 A; C=1-1119.
DR PDB; 5E18; X-ray; 3.30 A; C=1-1119.
DR PDB; 5I2D; X-ray; 4.41 A; C/N=1-1119.
DR PDB; 5TMC; X-ray; 2.71 A; C=1-1119.
DR PDB; 5TMF; X-ray; 3.00 A; C=1-1119.
DR PDB; 5VO8; X-ray; 3.30 A; C=1-1119.
DR PDB; 5VOI; X-ray; 2.80 A; C=1-1119.
DR PDB; 5X21; X-ray; 3.32 A; C=1-1119.
DR PDB; 5X22; X-ray; 3.35 A; C/M=1-1119.
DR PDB; 5XJ0; X-ray; 4.00 A; C=1-1119.
DR PDB; 6ASG; X-ray; 3.80 A; C=1-1119.
DR PDB; 6KQD; X-ray; 3.30 A; C/M=1-1119.
DR PDB; 6KQE; X-ray; 3.30 A; C=1-1119.
DR PDB; 6KQF; X-ray; 2.45 A; C=1-1119.
DR PDB; 6KQG; X-ray; 2.78 A; C=1-1119.
DR PDB; 6KQH; X-ray; 3.18 A; C=1-1119.
DR PDB; 6KQL; X-ray; 2.89 A; C=1-1119.
DR PDB; 6KQM; X-ray; 3.20 A; C=1-1119.
DR PDB; 6KQN; X-ray; 3.49 A; C=1-1119.
DR PDB; 6L74; X-ray; 3.12 A; C=1-1119.
DR PDB; 6LTS; X-ray; 3.45 A; C=1-1119.
DR PDB; 6M6A; EM; 5.00 A; C=1-1119.
DR PDB; 6M6B; EM; 4.10 A; C=1-1119.
DR PDB; 6M6C; EM; 3.10 A; C=1-1119.
DR PDB; 6OVR; X-ray; 2.84 A; C=1-1119.
DR PDB; 6OVY; X-ray; 3.00 A; C=1-1119.
DR PDB; 6OW3; X-ray; 2.77 A; C=1-1119.
DR PDB; 6OY5; X-ray; 3.10 A; C=1-1119.
DR PDB; 6OY6; X-ray; 3.10 A; C=1-1119.
DR PDB; 6OY7; X-ray; 3.04 A; C=1-1119.
DR PDB; 6P70; X-ray; 3.05 A; C=1-1119.
DR PDB; 6P71; X-ray; 2.92 A; C=1-1119.
DR PDB; 6WOX; X-ray; 3.14 A; C=1-1119.
DR PDB; 6WOY; X-ray; 3.00 A; C=1-1119.
DR PDB; 7EH0; X-ray; 2.81 A; C=1-1119.
DR PDB; 7EH1; X-ray; 2.90 A; C=1-1119.
DR PDB; 7EH2; X-ray; 3.34 A; C/M=1-1119.
DR PDB; 7MLB; X-ray; 3.60 A; C=1-1119.
DR PDB; 7MLI; X-ray; 3.60 A; C=1-1119.
DR PDB; 7MLJ; X-ray; 3.75 A; C=1-1119.
DR PDB; 7RDQ; EM; 3.00 A; C=1-1119.
DR PDBsum; 1IW7; -.
DR PDBsum; 1SMY; -.
DR PDBsum; 1ZYR; -.
DR PDBsum; 2A68; -.
DR PDBsum; 2A69; -.
DR PDBsum; 2A6E; -.
DR PDBsum; 2A6H; -.
DR PDBsum; 2BE5; -.
DR PDBsum; 2CW0; -.
DR PDBsum; 2O5I; -.
DR PDBsum; 2O5J; -.
DR PDBsum; 2PPB; -.
DR PDBsum; 3AOH; -.
DR PDBsum; 3AOI; -.
DR PDBsum; 3DXJ; -.
DR PDBsum; 3EQL; -.
DR PDBsum; 3WOD; -.
DR PDBsum; 3WOE; -.
DR PDBsum; 3WOF; -.
DR PDBsum; 4G7H; -.
DR PDBsum; 4G7O; -.
DR PDBsum; 4G7Z; -.
DR PDBsum; 4GZY; -.
DR PDBsum; 4GZZ; -.
DR PDBsum; 4MQ9; -.
DR PDBsum; 4OIN; -.
DR PDBsum; 4OIO; -.
DR PDBsum; 4OIP; -.
DR PDBsum; 4OIQ; -.
DR PDBsum; 4OIR; -.
DR PDBsum; 4Q4Z; -.
DR PDBsum; 4Q5S; -.
DR PDBsum; 4WQS; -.
DR PDBsum; 4WQT; -.
DR PDBsum; 5D4C; -.
DR PDBsum; 5D4D; -.
DR PDBsum; 5D4E; -.
DR PDBsum; 5E17; -.
DR PDBsum; 5E18; -.
DR PDBsum; 5I2D; -.
DR PDBsum; 5TMC; -.
DR PDBsum; 5TMF; -.
DR PDBsum; 5VO8; -.
DR PDBsum; 5VOI; -.
DR PDBsum; 5X21; -.
DR PDBsum; 5X22; -.
DR PDBsum; 5XJ0; -.
DR PDBsum; 6ASG; -.
DR PDBsum; 6KQD; -.
DR PDBsum; 6KQE; -.
DR PDBsum; 6KQF; -.
DR PDBsum; 6KQG; -.
DR PDBsum; 6KQH; -.
DR PDBsum; 6KQL; -.
DR PDBsum; 6KQM; -.
DR PDBsum; 6KQN; -.
DR PDBsum; 6L74; -.
DR PDBsum; 6LTS; -.
DR PDBsum; 6M6A; -.
DR PDBsum; 6M6B; -.
DR PDBsum; 6M6C; -.
DR PDBsum; 6OVR; -.
DR PDBsum; 6OVY; -.
DR PDBsum; 6OW3; -.
DR PDBsum; 6OY5; -.
DR PDBsum; 6OY6; -.
DR PDBsum; 6OY7; -.
DR PDBsum; 6P70; -.
DR PDBsum; 6P71; -.
DR PDBsum; 6WOX; -.
DR PDBsum; 6WOY; -.
DR PDBsum; 7EH0; -.
DR PDBsum; 7EH1; -.
DR PDBsum; 7EH2; -.
DR PDBsum; 7MLB; -.
DR PDBsum; 7MLI; -.
DR PDBsum; 7MLJ; -.
DR PDBsum; 7RDQ; -.
DR AlphaFoldDB; Q8RQE9; -.
DR SMR; Q8RQE9; -.
DR DIP; DIP-47011N; -.
DR IntAct; Q8RQE9; 7.
DR STRING; 300852.55773195; -.
DR DrugBank; DB08266; Methyl [(1E,5R)-5-{3-[(2E,4E)-2,5-dimethyl-2,4-octadienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate.
DR DrugBank; DB08226; Myxopyronin B.
DR DrugBank; DB04788; Tagetitoxin.
DR PRIDE; Q8RQE9; -.
DR EnsemblBacteria; BAD71636; BAD71636; BAD71636.
DR GeneID; 3169736; -.
DR KEGG; ttj:TTHA1813; -.
DR PATRIC; fig|300852.9.peg.1784; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_1_0; -.
DR OMA; FMTWEGY; -.
DR PhylomeDB; Q8RQE9; -.
DR BRENDA; 2.7.7.6; 2305.
DR EvolutionaryTrace; Q8RQE9; -.
DR PRO; PR:Q8RQE9; -.
DR Proteomes; UP000000532; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 1.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA-directed RNA polymerase; Nucleotidyltransferase;
KW Reference proteome; Transcription; Transferase.
FT CHAIN 1..1119
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000047985"
FT STRAND 2..5
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 20..29
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 31..33
FT /evidence="ECO:0007829|PDB:2O5I"
FT HELIX 36..38
FT /evidence="ECO:0007829|PDB:6KQF"
FT HELIX 43..51
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 53..56
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 59..61
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 64..68
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 80..85
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 91..94
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 98..100
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 103..105
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 107..109
FT /evidence="ECO:0007829|PDB:2O5I"
FT STRAND 117..119
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 123..125
FT /evidence="ECO:0007829|PDB:1IW7"
FT STRAND 129..132
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 134..136
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 138..142
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 146..149
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 152..154
FT /evidence="ECO:0007829|PDB:6KQF"
FT STRAND 159..162
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 166..169
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 172..177
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 178..180
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 181..191
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 193..200
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 204..212
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 213..216
FT /evidence="ECO:0007829|PDB:6KQF"
FT HELIX 218..221
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 225..228
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 231..241
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 242..244
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 250..252
FT /evidence="ECO:0007829|PDB:6OVY"
FT HELIX 253..257
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 259..264
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 269..271
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 274..278
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 280..284
FT /evidence="ECO:0007829|PDB:5TMC"
FT TURN 287..290
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 294..296
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 297..302
FT /evidence="ECO:0007829|PDB:6KQF"
FT HELIX 303..314
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 325..327
FT /evidence="ECO:0007829|PDB:4G7O"
FT TURN 328..330
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 331..334
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 336..361
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 364..366
FT /evidence="ECO:0007829|PDB:6KQF"
FT TURN 370..372
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 376..387
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 390..394
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 401..408
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 409..418
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 419..421
FT /evidence="ECO:0007829|PDB:5TMC"
FT HELIX 425..428
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 432..434
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 435..437
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 440..443
FT /evidence="ECO:0007829|PDB:2O5I"
FT STRAND 445..448
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 450..455
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 456..458
FT /evidence="ECO:0007829|PDB:2O5J"
FT STRAND 460..462
FT /evidence="ECO:0007829|PDB:3DXJ"
FT STRAND 463..465
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 467..475
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 478..486
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 488..493
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 494..497
FT /evidence="ECO:0007829|PDB:6KQF"
FT STRAND 499..501
FT /evidence="ECO:0007829|PDB:2CW0"
FT STRAND 503..508
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 511..524
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 526..528
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 531..533
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 536..539
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 542..545
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 550..552
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 555..565
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 571..573
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 578..580
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 584..590
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 594..596
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 598..606
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 608..615
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 616..618
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 619..621
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 622..624
FT /evidence="ECO:0007829|PDB:6OY6"
FT STRAND 628..630
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 634..637
FT /evidence="ECO:0007829|PDB:6KQF"
FT STRAND 654..657
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 661..666
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 669..675
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 680..683
FT /evidence="ECO:0007829|PDB:6KQF"
FT STRAND 684..691
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 693..696
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 697..700
FT /evidence="ECO:0007829|PDB:6KQF"
FT STRAND 703..713
FT /evidence="ECO:0007829|PDB:3WOE"
FT STRAND 727..729
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 731..734
FT /evidence="ECO:0007829|PDB:3WOE"
FT HELIX 735..737
FT /evidence="ECO:0007829|PDB:1IW7"
FT TURN 738..740
FT /evidence="ECO:0007829|PDB:1IW7"
FT STRAND 741..743
FT /evidence="ECO:0007829|PDB:3WOE"
FT STRAND 754..756
FT /evidence="ECO:0007829|PDB:3WOE"
FT STRAND 758..761
FT /evidence="ECO:0007829|PDB:3WOE"
FT STRAND 762..766
FT /evidence="ECO:0007829|PDB:1IW7"
FT HELIX 769..778
FT /evidence="ECO:0007829|PDB:3WOE"
FT STRAND 785..787
FT /evidence="ECO:0007829|PDB:3WOE"
FT STRAND 798..807
FT /evidence="ECO:0007829|PDB:3WOE"
FT TURN 808..812
FT /evidence="ECO:0007829|PDB:5TMC"
FT STRAND 819..829
FT /evidence="ECO:0007829|PDB:3WOE"
FT STRAND 838..840
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 842..844
FT /evidence="ECO:0007829|PDB:3EQL"
FT STRAND 846..853
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 855..857
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 862..864
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 868..870
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 874..880
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 883..896
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 899..902
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 905..907
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 911..932
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 938..948
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 949..951
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 955..957
FT /evidence="ECO:0007829|PDB:5TMC"
FT HELIX 959..968
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 977..979
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 980..982
FT /evidence="ECO:0007829|PDB:5D4D"
FT STRAND 987..997
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 1001..1003
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 1006..1010
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 1015..1017
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 1024..1026
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 1030..1032
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 1034..1042
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 1047..1053
FT /evidence="ECO:0007829|PDB:2A6H"
FT TURN 1054..1058
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 1060..1071
FT /evidence="ECO:0007829|PDB:2A6H"
FT HELIX 1083..1094
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 1098..1102
FT /evidence="ECO:0007829|PDB:2BE5"
FT STRAND 1104..1106
FT /evidence="ECO:0007829|PDB:2A6H"
FT STRAND 1114..1117
FT /evidence="ECO:0007829|PDB:2A6H"
SQ SEQUENCE 1119 AA; 125264 MW; C1260F31CEC6B40D CRC64;
MEIKRFGRIR EVIPLPPLTE IQVESYRRAL QADVPPEKRE NVGIQAAFRE TFPIEEEDKG
KGGLVLDFLE YRLGEPPFPQ DECREKDLTY QAPLYARLQL IHKDTGLIKE DEVFLGHIPL
MTEDGSFIIN GADRVIVSQI HRSPGVYFTP DPARPGRYIA SIIPLPKRGP WIDLEVEPNG
VVSMKVNKRK FPLVLLLRVL GYDQETLARE LGAYGELVQG LMDESVFAMR PEEALIRLFT
LLRPGDPPKR DKAVAYVYGL IADPRRYDLG EAGRYKAEEK LGIRLSGRTL ARFEDGEFKD
EVFLPTLRYL FALTAGVPGH EVDDIDHLGN RRIRTVGELM TDQFRVGLAR LARGVRERML
MGSEDSLTPA KLVNSRPLEA AIREFFSRSQ LSQFKDETNP LSSLRHKRRI SALGPGGLTR
ERAGFDVRDV HRTHYGRICP VETPEGANIG LITSLAAYAR VDELGFIRTP YRRVVGGVVT
DEVVYMTATE EDRYTIAQAN TPLEGNRIAA ERVVARRKGE PVIVSPEEVE FMDVSPKQVF
SVNTNLIPFL EHDDANRALM GSNMQTQAVP LIRAQAPVVM TGLEERVVRD SLAALYAEED
GEVAKVDGNR IVVRYEDGRL VEYPLRRFYR SNQGTALDQR PRVVVGQRVR KGDLLADGPA
SENGFLALGQ NVLVAIMPFD GYNFEDAIVI SEELLKRDFY TSIHIERYEI EARDTKLGPE
RITRDIPHLS EAALRDLDEE GVVRIGAEVK PGDILVGRTS FKGESEPTPE ERLLRSIFGE
KARDVKDTSL RVPPGEGGIV VRTVRLRRGD PGVELKPGVR EVVRVYVAQK RKLQVGDKLA
NRHGNKGVVA KILPVEDMPH LPDGTPVDVI LNPLGVPSRM NLGQILETHL GLAGYFLGQR
YISPIFDGAK EPEIKELLAQ AFEVYFGKRK GEGFGVDKRE VEVLRRAEKL GLVTPGKTPE
EQLKELFLQG KVVLYDGRTG EPIEGPIVVG QMFIMKLYHM VEDKMHARST GPYSLITQQP
LGGKAQFGGQ RFGEMEVWAL EAYGAAHTLQ EMLTLKSDDI EGRNAAYEAI IKGEDVPEPS
VPESFRVLVK ELQALALDVQ TLDEKDNPVD IFEGLASKR
