RPOB_TRIL1
ID RPOB_TRIL1 Reviewed; 1497 AA.
AC B3E7S8;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 22-JUL-2008, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Glov_1339;
OS Trichlorobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) (Geobacter
OS lovleyi).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC Geobacteraceae; Trichlorobacter.
OX NCBI_TaxID=398767;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1151 / DSM 17278 / SZ;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Meincke L., Brettin T.,
RA Detter J.C., Han C., Tapia R., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Sung Y., Fletcher K.E.,
RA Ritalahti K.M., Loeffler F.E., Richardson P.;
RT "Complete sequence of chromosome of Geobacter lovleyi SZ.";
RL Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP001089; ACD95060.1; -; Genomic_DNA.
DR RefSeq; WP_012469406.1; NC_010814.1.
DR AlphaFoldDB; B3E7S8; -.
DR SMR; B3E7S8; -.
DR STRING; 398767.Glov_1339; -.
DR PRIDE; B3E7S8; -.
DR EnsemblBacteria; ACD95060; ACD95060; Glov_1339.
DR KEGG; glo:Glov_1339; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_1_7; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000002420; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1497
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_1000141700"
SQ SEQUENCE 1497 AA; 167394 MW; ADD8CE126267E14C CRC64;
MAYSIANNHL LRKNFATIKN IIDIPNLIDI QKNSYRRFLQ SDVPLDLRKN IGLEAVFRSV
FPIKDFSETS SLEYVSYTLS KPKYDVEECH QRGMTYAAPM KVKVRLVIWD SGKESGVRGV
KDIKEQEVYF GEIPLMTENG TFIINGTERV IVSQLHRSPG VFFDHDKGKT HSSGKVLYSA
RVIPYRGSWL DFEFDHKDIL FVRIDRRRKM PATVLLKALG YSVEHLLNYY YKSEQIYIAA
GELRKGIEPE LLTMQKAVVD VADANGEVIV KANRKFTKAS IKKLLDHGVT SIPTSSESII
GRYASADVVD PVTGEILLEC NQELTADKLD ELRQKEVTTF NLLYIDGLNV TSSFRDTLLA
DKISSSDEAL IEIYRRLRPG DPPTLKSSLA LFDNLFFNPE RYDLSAVGRL KLNFKLGLKV
WPDCTILNGP TMLTAAELQN AEQLIGSLLN GTRPVDLALK DRLSSDLTKS LKKLDLKQPV
PERLLEQLAD ELNSAVANAE FFQRDLIAGL ELPESFIKLM DLIEQGGYDE NRRRIEGLRR
NRMLLEVAYG DSVECCNRND ILEIVRYLIE LKNGRGAIDD IDHLGNRRVR AVGELLENQY
RIGLVRMERA IKERMSLQEV ENLMPHDLIN SKPVSAVVKE FFGSSQLSQF MDQTNPLSEV
THKRRLSALG PGGLTRERAG FEVRDVHPTH YGRVCPIETP EGPNIGLIAS LSTYARINEH
GFVETPYRLV REGQVTSEVK FFSALEEEGH AIAQANALVD QDGRFINEYV SARKSGEFVL
VQRDEIELMD VAPKQLVSVA AALIPFLEND DANRALMGSN MQRQAVPLLR ADSPLVGTGM
ERIVAKDSGV SVIARHNGVV DAVDAGRIVI KIDEEEYDET GTGVDIYNLV KFSRSNQNTC
INQKPVVKVG DKVKRGDVIA DGPSTDMGEL ALGQNIIVAF MPWGGYNFED SILVSERLTK
DDRYTSIHIE EFECVARDTK LGKEEITADI PNLGEEALKD LDESGIIRIG AEVKPGDILV
GKITPKGETQ LSPEEKLLRA IFGEKAGDVR DTSLTIPPGV EGTVIGAKVF SRKGNDKDAR
TELIEKIEEE KLRKDEQDEV RIIRDSARGK LKRLLVGKTA GAKIEDRHGV TVLAKGKKIT
DELLESLTMD RWATISVSDG TDVEEKVAEV LSKLNEQVEL IRGVFDDKVQ KLRRGDDLPP
GVIKMVKVYV AIKRKLQVGD KMAGRHGNKG VVSRILPEED MPYMDDGRPV EIVLNPLGVP
SRMNVGQILE THLGWAAKGL GWKIQKMLEE HTSEENLKKF IRETYDNADF NKILDTMDRE
ELLLVARRLS RGVPMASPVF EGAGEAKIKE LLTRAGFATN GQVTLFDGRT GEPFKHKVTV
GIMYVLKLHH LVDDKIHARS IGPYSLVTQQ PLGGKAQFGG QRLGEMEVWA MEAYGCSYAL
QEFLTVKSDD VSGRTRMYEA IVKGKHTLEP GLPESFNVLI KELQSLCLDV ELLEGDE
