RPOB_XANC5
ID RPOB_XANC5 Reviewed; 1383 AA.
AC Q3BWZ1;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=XCV0991;
OS Xanthomonas campestris pv. vesicatoria (strain 85-10).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xanthomonas.
OX NCBI_TaxID=316273;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=85-10;
RX PubMed=16237009; DOI=10.1128/jb.187.21.7254-7266.2005;
RA Thieme F., Koebnik R., Bekel T., Berger C., Boch J., Buettner D.,
RA Caldana C., Gaigalat L., Goesmann A., Kay S., Kirchner O., Lanz C.,
RA Linke B., McHardy A.C., Meyer F., Mittenhuber G., Nies D.H.,
RA Niesbach-Kloesgen U., Patschkowski T., Rueckert C., Rupp O., Schneiker S.,
RA Schuster S.C., Vorhoelter F.J., Weber E., Puehler A., Bonas U., Bartels D.,
RA Kaiser O.;
RT "Insights into genome plasticity and pathogenicity of the plant pathogenic
RT Bacterium Xanthomonas campestris pv. vesicatoria revealed by the complete
RT genome sequence.";
RL J. Bacteriol. 187:7254-7266(2005).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM039952; CAJ22622.1; -; Genomic_DNA.
DR RefSeq; WP_011346538.1; NZ_CP017190.1.
DR AlphaFoldDB; Q3BWZ1; -.
DR SMR; Q3BWZ1; -.
DR STRING; 456327.BJD11_17780; -.
DR EnsemblBacteria; CAJ22622; CAJ22622; XCV0991.
DR KEGG; xcv:XCV0991; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_0_6; -.
DR OMA; FMTWEGY; -.
DR Proteomes; UP000007069; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 3.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW Transferase.
FT CHAIN 1..1383
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000224121"
SQ SEQUENCE 1383 AA; 154285 MW; DD270C7C89CAF5DB CRC64;
MTSYSFTEKK RIRKDFGKQR SILEVPFLLA IQVDSYREFL QEDVEPNKRK DLGLHAALKS
VFPISSYSGN AALEYVGYKL GQPVFDEREC RQRGMSYGAP LRVTVRLVIY DRESSTKAIK
YVKEQEVYLG EIPLMTGNGT FIVNGTERVI VSQLHRSPGV FFDHDRGKTH SSGKLLYSAR
IIPYRGSWLD FEFDPKDALF TRIDRRRKLP VSILLRALGY SNEEMLAEFF EINTFHINPD
EGVQLELVPE RLRGETLNFD LADGDKVIVE AGKRITARHV KQLEAAGVAA LAVPDDYLVG
RILSHDVVDG STGELLANAN DEINEDQLAA FRKAGVDAVG TLWVNDLDRG PYLSNTLRID
PTKTQLEALV EIYRMMRPGE PPTKEAAQNL FHNLFFTFER YDLSTVGRMK FNRRVGRKDV
LGESVLYDKK YFAERNDEES KRLVAEHADT SDILEVIKVL TEIRNGRGVV DDIDHLGNRR
VRSVGEMAEN VFRVGLVRVE RAVKERLSMA ESEGLTPQEL INAKPVAAAI KEFFGSSQLS
QFMDQNNPLS EVTHKRRVFA LGPGGLTRER AGFEVRDVHP THYGRVCTIE TPEGPNIGLI
NSLAVFARTN QYGFLETPYR KVLDGKVSDD VEYLSAIEEN EYVIAQANAL TDAKNMLTEQ
FVPCRFQGES LLKPPSEVHF MDVSPMQTVS VAAALVPFLE HDDANRALMG ANMQRQAVPT
LRSQKPLVGT GIERAVARDS GVTVNALRGG VIEQIDAARI VVKVNEAEIG GGTDAGVDIY
NLIKYTRSNQ NTCINQRPLV NVGDVIARGD VLADGPSTDI GELALGQNML IAFMPWNGYN
FEDSILLSER VVEEDRYTTI HIEELTCVAR DTKLGPEEIS ADIPNVSEQA LNRLDESGVV
YIGAEVRAGD IMVGKVTPKG ESQLTPEEKL LRAIFGEKAS DVKDSSLRVP PGMDGTVIDV
QVFTRDGIEK DKRARQIEEN EIKRVKKDFD DQFRILEAAI YARLRSQIVG KVANGGANLK
KGDTVTDAYL DGLKKSDWFQ LRMKDEDAAD AIERAQKQIQ AHEKEFEARF ADKRGKITQG
DDLAPGVLKM VKVFLAVKRR IQPGDKMAGR HGNKGVVSNV VPVEDMPYMA TGESVDIVLN
PLGVPSRMNI GQILEVHLGW AAKGLGRKIQ RMLEAQAAVS ELRKFLNDIY NHDNAINAQR
VDLSQFSDEE LLNLGKNLID GVPMATPVFD GASEAEIKRM LELADLPQSG QTQLYDGRTG
EAFDRKTTVG YMHYLKLNHL VDDKMHARST GPYSLVTQQP LGGKAQFGGQ RFGEMEVWAL
EAYGAAYTLQ EMLTVKSDDV QGRNQMYKNI VDGEHEMVAG MPESFNVLVK EIRSLAINME
LEE