RPOB_XANP2
ID RPOB_XANP2 Reviewed; 1358 AA.
AC A7IKQ0;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Xaut_3364;
OS Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Xanthobacteraceae; Xanthobacter.
OX NCBI_TaxID=78245;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1158 / Py2;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D.,
RA Detter J.C., Han C., Tapia R., Brainard J., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Kim E., Ensigns S.A., Richardson P.;
RT "Complete sequence of chromosome of Xanthobacter autotrophicus Py2.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000781; ABS68593.1; -; Genomic_DNA.
DR RefSeq; WP_012115339.1; NC_009720.1.
DR AlphaFoldDB; A7IKQ0; -.
DR SMR; A7IKQ0; -.
DR STRING; 78245.Xaut_3364; -.
DR EnsemblBacteria; ABS68593; ABS68593; Xaut_3364.
DR KEGG; xau:Xaut_3364; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_0_5; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR PhylomeDB; A7IKQ0; -.
DR Proteomes; UP000002417; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 2.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 2.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1358
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_1000141751"
SQ SEQUENCE 1358 AA; 151769 MW; 7515A8F16290F193 CRC64;
MAQTFTGRKR IRKFFGKIKE VAEMPNLIEV QKASYDQFLQ IEEPKGGRDD DGLQAVFKSV
FPISDFSGAS MLEFVRYEFE PPKYDVDECR QRGMTFAAPL KVTLRLIVFD VDPETGAKSV
KDIKEQDVYT GDIPLMTMNG TFIVNGTERV IVSQMHRSPG VFFDHDKGKT HSSGKLLFAA
RIIPYRGSWL DIEFDAKDIV FARIDRRRKI PVTSLLYALG LDNEEILSTF YEKIPFTREK
GGWRMPFDPK RMKGYKAVAD LIDADTGEVV LEAGKKLTVR AGRQLAEKGL KALKISDEEM
IGQYIAEDLV DLTSGEIHAE AGEEITEKTL KLLEETGYNE IPVLDIDHVN TGAYIRNTLT
ADKNVTREDA LFDIYRVMRP GEPPTLDSAQ AMFHSLFFDS ERYDLSAVGR VKMNMRLDLD
CPDTVRVLRR DDILSVIRTL VELRDGKGEI DDIDHLGNRR VRSVGELMEN QYRVGLLRME
RAIKERMSSV DIDTVMPQDL INAKPVAAAV REFFGSSQLS QFMDQTNPLS EITHKRRLSA
LGPGGLTRER AGFEVRDVHP THYGRICPIE TPEGPNIGLI NSLATFARVN KYGFIEAPYR
RVVDSKVTDE VVYLSAMEEG KYYVAQANIP LDKDGRFEED LIVCRHAGDV LLVAPDRVDF
MDVSPKQLVS VAAALIPFLE NDDANRALMG SNMQRQAVPL VRSQAPLVGT GMEAVVARDS
GAAIAARRTG VIDQVDATRI VIRATEEADP SKSGVDIYRL MKFQRSNQST CINQRPLVRV
GDQVKKGDII ADGPSTELGE LALGRNVLVA FMPWNGYNFE DSILLSENIA KEDVFTSIHI
EEFEAMARDT KLGPEEITRD IPNVSEEALK NLDEAGIVYI GAEVRAGDIL VGKITPKGES
PMTPEEKLLR AIFGEKAADV RDTSLRLPPG TTGTIVEVRV FNRHGVDKDE RALAIEREEI
ERLAKDRDDE QAILDRNVYG RLIEILDGKT AIAGPKGFRK ETVVTREILT EYPRSQWWLF
AVADDAIMAE LEAIRAQYDD SKKRLEQRFL DKVEKLQRGD ELPPGVMKMV KVFVAVKRKI
QPGDKMAGRH GNKGVVSRIV PVEDMPFLED GTNVDIVLNP LGVPSRMNVG QILETHLGWA
CAGLGRQVAA AMEAYYGKQD LKPLRDRLET IYGKDEIEQL KDGELPELGE NLRKGVPMAT
PVFDGAHEAD IEQQLEKAGL DASGQSTLYD GRTGEPFDRK VTVGYIYMLK LHHLVDDKIH
ARSIGPYSLV TQQPLGGKAQ FGGQRFGEME VWALEAYGAA YTLQEMLTVK SDDVAGRTKV
YEAIVRGEDT FESGIPESFN VLVKEMRSLG LNVDLENS
