RPOB_ZYMMO
ID RPOB_ZYMMO Reviewed; 1401 AA.
AC Q5NPK5;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=ZMO0731;
OS Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC Zymomonadaceae; Zymomonas.
OX NCBI_TaxID=264203;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31821 / ZM4 / CP4;
RX PubMed=15592456; DOI=10.1038/nbt1045;
RA Seo J.-S., Chong H., Park H.S., Yoon K.-O., Jung C., Kim J.J., Hong J.H.,
RA Kim H., Kim J.-H., Kil J.-I., Park C.J., Oh H.-M., Lee J.-S., Jin S.-J.,
RA Um H.-W., Lee H.-J., Oh S.-J., Kim J.Y., Kang H.L., Lee S.Y., Lee K.J.,
RA Kang H.S.;
RT "The genome sequence of the ethanologenic bacterium Zymomonas mobilis
RT ZM4.";
RL Nat. Biotechnol. 23:63-68(2005).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; AE008692; AAV89355.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5NPK5; -.
DR SMR; Q5NPK5; -.
DR STRING; 264203.ZMO0731; -.
DR PRIDE; Q5NPK5; -.
DR EnsemblBacteria; AAV89355; AAV89355; ZMO0731.
DR KEGG; zmo:ZMO0731; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_3_5; -.
DR OMA; FMTWEGY; -.
DR Proteomes; UP000001173; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1401
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000224124"
SQ SEQUENCE 1401 AA; 156540 MW; A6B5B6647D09DD0E CRC64;
MGRLVVKRED YMATKASAIG HASVKKRIRK MFGNIHEVVD MPNLIEVQRD SYENFLRSRP
EDGYVSGLEK TLRSVFPIRD FGGVAELDFV QYELEEPKFD VDECRQRGIT YAAPMRVTLR
LIVFEVDPDT ETRSVLDIKE QDVYMGDMPL MTRNGTFFIN GTERVIVSQM HRSPGVLFDH
DKGKTHSSGK FLFAARVIPY RGSWLDFEFD AKDIVNVRID RKRKLPVTTL LYALGLNAEQ
ILHHFYNTIT FVRGDGGWKV PYVAESWRGR KPFFDIINGD TGEVVFPAGQ KISPRAANKA
GRDGLETLLI PTEEIYGHYA AYDVIDESTG RIWIEAGDEV TPENLELLDN AGVATLELLD
IDHVSTGPWI RNTLKADKAE DRDHALAEIY RVMRPGEPPT KETAEALFYG LFFDPERYDL
SAVGRVKLNM RLDLDCPDTV TTLRAEDILA VVKTLVDLKD GKGEVDDIDN LGNRRVRSVG
ELLENQYRVG LLRMERAVKE RMSSVDVSTV MPNDLINAKP AVAAVREFFG SSQLSQFMDQ
TNPLSEVTHK RRVSALGPGG LTRERAGFEV RDVHPTHYGR ICPIETPEGP NIGLINSLAT
FSRINKYGFI ETPYRKVVDH KVTNEVIYLS AMEESRYTVA QANAELDAEG HFVEELVSAR
EAGEFLMAPR EQITLMDVSP KQLVSVAASL IPFLENDDAN RALMGSNMQR QAVSLVRAEA
PFVGTGMEET VARDSGAAIS ARRAGIVDQV DASRIVIRTT GEIEAGKPGV DIYRLMKFQR
SNQSTCINQR PLVSVGDYVN AGDVLADGPS TELGELALGR NVLVAFMPWN GYNYEDSILI
SERIVKDDVF TSIHIDEFEV MARDTKLGPE DITRDIPNVG EDALRNLDEA GIVYIGAEVQ
PGDILVGKIT PKGESPMTPE EKLLRAIFGE KASDVRDTSL RLPPGVAGTI VDVRVFNRHG
VDKDERAMAI EREEIERLTK DREDERAILN RATYAQLQEK LLGQTVAAAP YKHIVKGARI
DIETLASVEP HKWFKFAVED DARQAELEAI KNQYDSADEA IRKRFEDRVE KAQRGDELPP
GVLKMVKVFV AVKRKLQPGD KMAGRHGNKG VISRILPAED MPFLADGTPV DIVLNPLGVP
SRMNIGQIFE THLGWAARGL GAKVRTALEE WREANADRYE WDFSPPEVVR ERMIEVYGEK
YAEDIKSRED REIVEMAGLL RNGVPMATPV FDGAKPEDIS EMLNLAGLDD SGQVELYDGR
TGEQFDRKVT VGYIYMLKLH HLVDDKIHAR SIGPYSLVTQ QPLGGKAQFG GQRFGEMEVW
ALQAYGAAYT LQEMLTVKSD DVVGRTKVYE AIVKGDDTFE AGIPESFNVL VKEMHSLGLN
VELKTSKAKD EDDSSFQVAA E
