AB41G_ORYSJ
ID AB41G_ORYSJ Reviewed; 1441 AA.
AC Q8GU83; C7IY70;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=ABC transporter G family member 41 {ECO:0000303|PubMed:18299247};
DE Short=OsABCG41 {ECO:0000303|PubMed:18299247};
DE AltName: Full=Pleiotropic drug resistance protein 2 {ECO:0000303|PubMed:12644668, ECO:0000303|PubMed:16506311};
DE Short=OsPDR2 {ECO:0000303|PubMed:16506311};
GN Name=ABCG41 {ECO:0000303|PubMed:18299247};
GN Synonyms=PDR2 {ECO:0000303|PubMed:12644668, ECO:0000303|PubMed:16506311};
GN OrderedLocusNames=Os02g0528900 {ECO:0000312|EMBL:BAH91729.1},
GN LOC_Os02g32690;
GN ORFNames=P0475F05.27 {ECO:0000312|EMBL:BAD25608.1},
GN P0476H10.11 {ECO:0000312|EMBL:BAD25425.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12644668; DOI=10.1104/pp.102.014720;
RA Jasinski M., Ducos E., Martinoia E., Boutry M.;
RT "The ATP-binding cassette transporters: structure, function, and gene
RT family comparison between rice and Arabidopsis.";
RL Plant Physiol. 131:1169-1177(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16506311; DOI=10.1016/j.febslet.2005.12.043;
RA Crouzet J., Trombik T., Fraysse A.S., Boutry M.;
RT "Organization and function of the plant pleiotropic drug resistance ABC
RT transporter family.";
RL FEBS Lett. 580:1123-1130(2006).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- FUNCTION: May be a general defense protein. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAH91729.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AJ535053; CAD59575.1; -; Genomic_DNA.
DR EMBL; AP004790; BAD25425.1; -; Genomic_DNA.
DR EMBL; AP004879; BAD25608.1; -; Genomic_DNA.
DR EMBL; AP008208; BAH91729.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014958; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; Q8GU83; -.
DR SMR; Q8GU83; -.
DR STRING; 4530.OS02T0528900-01; -.
DR PaxDb; Q8GU83; -.
DR PRIDE; Q8GU83; -.
DR InParanoid; Q8GU83; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC_2_trans.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013581; PDR_assoc.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF08370; PDR_assoc; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1441
FT /note="ABC transporter G family member 41"
FT /id="PRO_0000433453"
FT TRANSMEM 528..548
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 566..586
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 600..620
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 642..662
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 672..692
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 758..778
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1187..1207
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1215..1235
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1272..1292
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1300..1320
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1329..1349
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1357..1377
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1413..1433
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 159..432
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 510..722
FT /note="ABC transmembrane type-2 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00442"
FT DOMAIN 838..1090
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 1163..1379
FT /note="ABC transmembrane type-2 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00442"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 192..199
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 883..890
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 1441 AA; 162529 MW; CB6CAAC34C7FC5BB CRC64;
MEDKKQQQQQ QREEAEAEEE APVVPSSLRA AATCRSLSSL SSSLRWDHRG DDDEEEAELR
WAAIERLPTL DRMRTSVLSS EAVDVRRLGA AQRRVLVERL VADIQRDNLR LLRKQRRRME
RVGVRQPTVE VRWRNVRVEA DCQVVSGKPL PTLLNTVLAT ARGLSRRPHA RIPILNDVTG
ILKPSRLTLL LGPPGCGKTT LLLALAGKLD KNLKVTGEVE YNGANLNTFV PEKTSAYISQ
YDLHVPEMTV RETLDFSARF QGVGTRAEIM KEVIRREKEA GITPDPDIDT YMKAISVEGL
ERSMQTDYIM KIMGLDICAD IIVGDIMRRG ISGGEKKRLT TGEMIVGPSR ALFMDEISTG
LDSSTTFQIV SCLQQVAHIS ESTILVSLLQ PAPETYDLFD DIILMAEGKI VYHGSKSCIM
NFFESCGFKC PERKGAADFL QEVLSKKDQQ QYWSRTEETY NFVTIDHFCE KFKASQVGQN
LVEELANPFD KSEVYNNALS LNIYSLTKWD LLKACFAREI LLMRRNAFIY ITKVVQLGLL
AVITGTVFLR THMGVDRAHA DYYMGSLFYA LILLLVNGFP ELAIAVSRLP VFYKQRDYYF
YPAWAYAIPS FILKIPLSLV ESITWTSISY YLIGYTPEAS RFFCQLLILF LVHTGALSLF
RCVASYCQTM VASSVGGTMS FLVILLFGGF IIPRLSMPNW LKWGFWISPL SYAEIGLTGN
EFLAPRWLKT TTSGVTLGRR VLMDRGLDFS SYFYWISASA LIGFILLLNV GYAIGLTIKK
PTGTSRAIIS RDKFSTFDRR GKDMSKDMDN RMPKLQVGNA LAPNKTGTMV LPFSPLTISF
QDVNYYVDTP VEMREQGYKE RKLQLLHNIT GAFQPGVLSA LMGVTGAGKT TLLDVLAGRK
TGGVIEGDIR VGGYPKIQQT FARISGYCEQ TDVHSPQITV EESVAYSAWL RLPTEVDSKT
RREFVDEVIQ TIELDDIRDA LVGLPGVSGL STEQRKRLTI AVELVSNPSV IFMDEPTSGL
DARAAAIVMR AVKNVADTGR TVVCTIHQPS IEIFEAFDEL MLMKRGGELI YAGPLGLHSC
NVIHYFETIP GVPKIKDNYN PSTWMLEVTC ASMEAQLGVD FAQIYRESTM CKDKDALVKS
LSKPALGTSD LHFPTRFPQK FREQLKACIW KQCLSYWRSP SYNLVRILFI TISCIVFGVL
FWQQGDINHI NDQQGLFTIL GCMYGTTLFT GINNCQSVIP FISIERSVVY RERFAGMYSP
WAYSLAQVAM EIPYVLVQIL LIMFIAYPMI GYAWTAAKFF WFMYTIACTL LYFLYFGMMI
VSLTPNIQVA SILASMFYTL QNLMSGFIVP APQIPRWWIW LYYTSPLSWT LNVFFTTQFG
DEHQKEISVF GETKSVAAFI KDYFGFRHDL LPLAAIILAM FPILFAILFG LSISKLNFQR
R
