RPOE_ALKHC
ID RPOE_ALKHC Reviewed; 164 AA.
AC Q9K6D6;
DT 04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Probable DNA-directed RNA polymerase subunit delta;
DE AltName: Full=RNAP delta factor;
GN Name=rpoE; OrderedLocusNames=BH3793;
OS Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS / JCM 9153 / C-125) (Bacillus halodurans).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX NCBI_TaxID=272558;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT and genomic sequence comparison with Bacillus subtilis.";
RL Nucleic Acids Res. 28:4317-4331(2000).
CC -!- FUNCTION: Participates in both the initiation and recycling phases of
CC transcription. In the presence of the delta subunit, RNAP displays an
CC increased specificity of transcription, a decreased affinity for
CC nucleic acids, and an increased efficiency of RNA synthesis because of
CC enhanced recycling (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC subunits. The core is associated with a delta subunit and one of
CC several sigma factors (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RpoE family. {ECO:0000305}.
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DR EMBL; BA000004; BAB07512.1; -; Genomic_DNA.
DR PIR; A84124; A84124.
DR RefSeq; WP_010899918.1; NC_002570.2.
DR AlphaFoldDB; Q9K6D6; -.
DR SMR; Q9K6D6; -.
DR STRING; 272558.10176418; -.
DR EnsemblBacteria; BAB07512; BAB07512; BAB07512.
DR KEGG; bha:BH3793; -.
DR eggNOG; COG3343; Bacteria.
DR HOGENOM; CLU_116648_1_0_9; -.
DR OMA; TWGLRSW; -.
DR OrthoDB; 2007175at2; -.
DR Proteomes; UP000001258; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 1.10.10.1250; -; 1.
DR HAMAP; MF_00357; RNApol_bact_RpoE; 1.
DR InterPro; IPR007759; Asxl_HARE-HTH.
DR InterPro; IPR038087; RNAP_delta_N_dom_sf.
DR InterPro; IPR029757; RpoE.
DR Pfam; PF05066; HARE-HTH; 1.
DR TIGRFAMs; TIGR04567; RNAP_delt_lowGC; 1.
DR PROSITE; PS51913; HTH_HARE; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..164
FT /note="Probable DNA-directed RNA polymerase subunit delta"
FT /id="PRO_0000204311"
FT DOMAIN 14..81
FT /note="HTH HARE-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01261"
FT REGION 93..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..107
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..164
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 164 AA; 19213 MW; 26E91F666DE67C7A CRC64;
MKLAELSKEE IQELSMVEVA YLVMKETKEP FNYQDLLKKV AELKGMSEEQ MLDRIGYLYT
DLNIDGRFVT LGDNRWGLRS WYPLEQVEEE ITGPTKKKAK AKAEEEVDEL DENIEVFDDE
FEDLEDELDE LAESEDSDEE DEEFDEGDDI DELDDEFEES DDDL
