RPOE_BACP2
ID RPOE_BACP2 Reviewed; 179 AA.
AC A8FIE6;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 13-NOV-2007, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Probable DNA-directed RNA polymerase subunit delta {ECO:0000255|HAMAP-Rule:MF_00357};
DE AltName: Full=RNAP delta factor {ECO:0000255|HAMAP-Rule:MF_00357};
GN Name=rpoE {ECO:0000255|HAMAP-Rule:MF_00357}; OrderedLocusNames=BPUM_3361;
OS Bacillus pumilus (strain SAFR-032).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=315750;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAFR-032;
RX PubMed=17895969; DOI=10.1371/journal.pone.0000928;
RA Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D.,
RA Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H.,
RA Lee S., Nazareth L., Blyth P., Holder M., Buhay C., Tirumalai M.R., Liu Y.,
RA Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P.,
RA Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D.,
RA Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F.,
RA Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K.,
RA Weinstock G.M.;
RT "Paradoxical DNA repair and peroxide resistance gene conservation in
RT Bacillus pumilus SAFR-032.";
RL PLoS ONE 2:E928-E928(2007).
CC -!- FUNCTION: Participates in both the initiation and recycling phases of
CC transcription. In the presence of the delta subunit, RNAP displays an
CC increased specificity of transcription, a decreased affinity for
CC nucleic acids, and an increased efficiency of RNA synthesis because of
CC enhanced recycling. {ECO:0000255|HAMAP-Rule:MF_00357}.
CC -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC subunits. The core is associated with a delta subunit and one of
CC several sigma factors. {ECO:0000255|HAMAP-Rule:MF_00357}.
CC -!- SIMILARITY: Belongs to the RpoE family. {ECO:0000255|HAMAP-
CC Rule:MF_00357}.
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DR EMBL; CP000813; ABV64013.1; -; Genomic_DNA.
DR RefSeq; WP_012011572.1; NZ_VEIS01000002.1.
DR AlphaFoldDB; A8FIE6; -.
DR SMR; A8FIE6; -.
DR STRING; 315750.BPUM_3361; -.
DR EnsemblBacteria; ABV64013; ABV64013; BPUM_3361.
DR KEGG; bpu:BPUM_3361; -.
DR eggNOG; COG3343; Bacteria.
DR HOGENOM; CLU_116648_1_0_9; -.
DR OMA; TWGLRSW; -.
DR OrthoDB; 2007175at2; -.
DR Proteomes; UP000001355; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 1.10.10.1250; -; 1.
DR HAMAP; MF_00357; RNApol_bact_RpoE; 1.
DR InterPro; IPR007759; Asxl_HARE-HTH.
DR InterPro; IPR038087; RNAP_delta_N_dom_sf.
DR InterPro; IPR029757; RpoE.
DR Pfam; PF05066; HARE-HTH; 1.
DR TIGRFAMs; TIGR04567; RNAP_delt_lowGC; 1.
DR PROSITE; PS51913; HTH_HARE; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..179
FT /note="Probable DNA-directed RNA polymerase subunit delta"
FT /id="PRO_1000059839"
FT DOMAIN 14..81
FT /note="HTH HARE-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01261"
FT REGION 108..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..179
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 179 AA; 21112 MW; 7B8F0048A46B6E22 CRC64;
MSLKEYSQEQ LKHMSLVELA YEIFRDSKTP ITFSELIDEM VRLQGIQKSD LDDRLAQFYT
DLNIDGRFIS LGDQRWGLRS WYPVDQIEEE VQPAVKTKAK KKKTKAAVVE EDFDEIEEEE
EIEELEEDLD LVEDDDDLDL DDDEEIEEEI EDFDEDDDED DDGLTEIDED DLDDNEEEK
