RPOE_LACLA
ID RPOE_LACLA Reviewed; 187 AA.
AC Q9CHT4;
DT 04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
DT 04-MAY-2001, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Probable DNA-directed RNA polymerase subunit delta;
DE AltName: Full=RNAP delta factor;
GN Name=rpoE; OrderedLocusNames=LL0634; ORFNames=L0141;
OS Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=272623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IL1403;
RX PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA Ehrlich S.D., Sorokin A.;
RT "The complete genome sequence of the lactic acid bacterium Lactococcus
RT lactis ssp. lactis IL1403.";
RL Genome Res. 11:731-753(2001).
CC -!- FUNCTION: Participates in both the initiation and recycling phases of
CC transcription. In the presence of the delta subunit, RNAP displays an
CC increased specificity of transcription, a decreased affinity for
CC nucleic acids, and an increased efficiency of RNA synthesis because of
CC enhanced recycling (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC subunits. The core is associated with a delta subunit and one of
CC several sigma factors (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RpoE family. {ECO:0000305}.
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DR EMBL; AE005176; AAK04732.1; -; Genomic_DNA.
DR PIR; B86704; B86704.
DR RefSeq; NP_266790.1; NC_002662.1.
DR RefSeq; WP_003129551.1; NC_002662.1.
DR AlphaFoldDB; Q9CHT4; -.
DR SMR; Q9CHT4; -.
DR STRING; 272623.L0141; -.
DR PaxDb; Q9CHT4; -.
DR EnsemblBacteria; AAK04732; AAK04732; L0141.
DR KEGG; lla:L0141; -.
DR PATRIC; fig|272623.7.peg.678; -.
DR eggNOG; COG3343; Bacteria.
DR HOGENOM; CLU_116648_0_0_9; -.
DR OMA; TWGLRSW; -.
DR Proteomes; UP000002196; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 1.10.10.1250; -; 1.
DR HAMAP; MF_00357; RNApol_bact_RpoE; 1.
DR InterPro; IPR007759; Asxl_HARE-HTH.
DR InterPro; IPR038087; RNAP_delta_N_dom_sf.
DR InterPro; IPR029757; RpoE.
DR Pfam; PF05066; HARE-HTH; 1.
DR TIGRFAMs; TIGR04567; RNAP_delt_lowGC; 1.
DR PROSITE; PS51913; HTH_HARE; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..187
FT /note="Probable DNA-directed RNA polymerase subunit delta"
FT /id="PRO_0000204313"
FT DOMAIN 14..81
FT /note="HTH HARE-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01261"
FT REGION 97..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..187
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 187 AA; 21387 MW; 2A8E30B4BCFD58C7 CRC64;
MKITALEGQK ISELSMIEVA HALLEQNGKE MQFSEIIRAI QDYLEKSDDE IKASISRFYT
EINTDGSFIP LGNNIWALRS WYAIDEIDEE VIALDEIEDE EEEKPAKKRK KVNAFGIEDE
IDPEDEEGTK ETTEEDMSYD TQAEDEDKDD VAAYDAELAE VELDNVDEEV DIDVEDDEDD
SDDTDED
