ID   RPOE_LIGS1              Reviewed;         196 AA.
AC   Q1WV31;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Probable DNA-directed RNA polymerase subunit delta {ECO:0000255|HAMAP-Rule:MF_00357};
DE   AltName: Full=RNAP delta factor {ECO:0000255|HAMAP-Rule:MF_00357};
GN   Name=rpoE {ECO:0000255|HAMAP-Rule:MF_00357}; OrderedLocusNames=LSL_0341;
OS   Ligilactobacillus salivarius (strain UCC118) (Lactobacillus salivarius).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Ligilactobacillus.
OX   NCBI_TaxID=362948;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCC118;
RX   PubMed=16617113; DOI=10.1073/pnas.0511060103;
RA   Claesson M.J., Li Y., Leahy S., Canchaya C., van Pijkeren J.P.,
RA   Cerdeno-Tarraga A.M., Parkhill J., Flynn S., O'Sullivan G.C., Collins J.K.,
RA   Higgins D., Shanahan F., Fitzgerald G.F., van Sinderen D., O'Toole P.W.;
RT   "Multireplicon genome architecture of Lactobacillus salivarius.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:6718-6723(2006).
CC   -!- FUNCTION: Participates in both the initiation and recycling phases of
CC       transcription. In the presence of the delta subunit, RNAP displays an
CC       increased specificity of transcription, a decreased affinity for
CC       nucleic acids, and an increased efficiency of RNA synthesis because of
CC       enhanced recycling. {ECO:0000255|HAMAP-Rule:MF_00357}.
CC   -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC       subunits. The core is associated with a delta subunit and one of
CC       several sigma factors. {ECO:0000255|HAMAP-Rule:MF_00357}.
CC   -!- SIMILARITY: Belongs to the RpoE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00357}.
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DR   EMBL; CP000233; ABD99154.1; -; Genomic_DNA.
DR   RefSeq; WP_011475701.1; NC_007929.1.
DR   RefSeq; YP_535237.1; NC_007929.1.
DR   AlphaFoldDB; Q1WV31; -.
DR   SMR; Q1WV31; -.
DR   STRING; 362948.LSL_0341; -.
DR   EnsemblBacteria; ABD99154; ABD99154; LSL_0341.
DR   GeneID; 57058795; -.
DR   KEGG; lsl:LSL_0341; -.
DR   PATRIC; fig|362948.14.peg.417; -.
DR   HOGENOM; CLU_116648_0_0_9; -.
DR   OMA; TWGLRSW; -.
DR   Proteomes; UP000006559; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.1250; -; 1.
DR   HAMAP; MF_00357; RNApol_bact_RpoE; 1.
DR   InterPro; IPR007759; Asxl_HARE-HTH.
DR   InterPro; IPR038087; RNAP_delta_N_dom_sf.
DR   InterPro; IPR029757; RpoE.
DR   Pfam; PF05066; HARE-HTH; 1.
DR   TIGRFAMs; TIGR04567; RNAP_delt_lowGC; 1.
DR   PROSITE; PS51913; HTH_HARE; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..196
FT                   /note="Probable DNA-directed RNA polymerase subunit delta"
FT                   /id="PRO_0000303129"
FT   DOMAIN          14..81
FT                   /note="HTH HARE-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01261"
FT   REGION          119..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        119..150
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        163..178
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   196 AA;  22660 MW;  4A58996829E13008 CRC64;
     MELEKFKDAN KDELSMIEVA HEILHQRGET MAFADLTNEI QVYLGKSDEE IRDRLAQFYT
     DLNIDGSFIS LGDNVWGLRS WYPYDSIDEA LVHGEDEEDE ERPRKKRKKV NAFLADVSDD
     DDVIDYDDDD PEDEDLDNDY DDEDDDDDEG SHELKQYTKD LDDIDDGDDP EDELADGIEG
     QLTEFSDADL DEENQD